1.
J Asian Nat Prod Res
; 16(2): 175-80, 2014.
Article
in English
| MEDLINE
| ID: mdl-24215489
ABSTRACT
Two new 20α-ursane-type triterpenoids (1-2) were isolated from the roots of Ilex cornuta, along with three known triterpenoids (3-5). The structures of compounds 1-2 were determined as 3ß, 23-dihydroxy-20α(H)-urs-12-en-28-oic acid (1), 3ß,19α,23-trihydroxy-20α(H)-urs-12-en-28-oic acid 3ß-O-α-l-arabinopyranoside (2), on the basis of hydrolysis and spectral evidence, including 1D- and 2D-NMR and high-resolution electrospray ionization mass spectrometry analyses. These pure isolates (1-5) were tested for their cytotoxic activities by MTT assay.