ABSTRACT
In the current work, a novel hybrid laminate with negative Poisson's ratio (NPR) is developed by considering auxetic laminate which is composed of carbon nanotube-reinforced composite (CNTRC) and fiber-reinforced composite (FRC) materials. The maximum magnitude of out-of-plane NPR is identified in the case of (20 F/20 C/-20 C/20 C) S laminate as well. Meanwhile, a method for the geometric non-linear analysis of hybrid laminated beam with NPR including the non-linear bending, free, and forced vibrations is proposed. The beam deformation is modeled by combining higher-order shear-deformation theory (HSDT) and large deflection theory. Based on a two-step perturbation approach, the asymptotic solutions of the governing equations are obtained to capture the linear and non-linear frequencies and load-deflection curves. Moreover, a two-step perturbation methodology in conjunction with fourth-order Runge-Kutta method is employed to solve the forced-vibration problem. Several key factors, such as CNT distribution, variations in the elastic foundation, and thermal stress, are considered in the exhaustive analysis. Theoretical results for some particular cases are given to examine the geometric non-linearity behavior of hybrid beam with NPR as well as positive Poisson's ratio (PPR).
ABSTRACT
OBJECTIVE: To study the correlation between Chinese medicine syndrome types of polycystic ovary syndrome (PCOS) and ovulation induction effect, and its clinical significance. METHODS: Eighty patients with clinically confirmed PCOS were syndrome differentiated as four types, i.e., Shen-yin deficiency syndrome (21 cases), Shen-yang deficiency syndrome (18 cases), phlegm-dampness accumulation syndrome (19 cases), and Gan-stagnancy transformed heat syndrome (22 cases). They all took 100 mg clomiphene as the ovulation induction for 5 successive days. Results of ovulation in all patients were analyzed and compared. RESULTS: Ovulation induction and the conception rate were sequenced from high to low as follows: Shen-yang deficiency syndrome (66.7%, 22.2%), Gan-stagnancy transformed heat syndrome (59.1%, 18.2%), Shen-yin deficiency syndrome (28.6%, 9.5%), and phlegm-dampness accumulation syndrome (26.3%, 5.3%). Significant difference was shown in ovulation induction results when compared Shen-yang deficiency syndrome with Shen-yin deficiency syndrome and phlegm-dampness accumulation syndrome (P<0.05) as well as when compared Ganstagnancy transformed heat syndrome with Shen-yin deficiency syndrome and phlegm-dampness accumulation syndrome (P<0.05). Significant difference was shown in the conception rate between Shen-yang deficiency syndrome and phlegm-dampness accumulation syndrome (P<0.05). CONCLUSION: The effects of ovulation induction in patients of phlegm-dampness accumulation syndrome and of Shen-yin deficiency syndrome were poorer than those in patients of Shen-yang deficiency syndrome and Gan-stagnancy transformed heat syndrome, which indicated the reproduction endocrine abnormality or the metabolism abnormality degree of the former two syndrome types were more server than the latter two syndrome types.