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1.
Postepy Hig Med Dosw (Online) ; 69: 1196-204, 2015 Oct 29.
Article in English | MEDLINE | ID: mdl-26561846

ABSTRACT

Nanotechnologies are new areas of research focusing on affecting matter at the atomic and molecular levels. It is beyond doubt that modern medicine can benefit greatly from it; thus nanomedicine has become one of the main branches of nanotechnological research. Currently it focuses on developing new methods of preventing, diagnosing and treating various diseases. Nanomaterials show very high efficiency in destroying cancer cells and are already undergoing clinical trials. The results are so promising that nanomaterials might become an alternative to traditional cancer therapy, mostly due to the fact that they allow cancer cells to be targeted specifically and enable detailed imaging of tissues, making planning further therapy much easier. Nanoscience might also be a source of the needed breakthrough in the fight against atherosclerosis, since nanostructures may be used in both preventing and increasing the stability of atherosclerotic lesions. One area of interest is creating nanomaterials that are not only efficient, but also well tolerated by the human body. Other potential applications of nanotechnology in medicine include: nanoadjuvants with immunomodulatory properties used to deliver vaccine antigens; the nano-knife, an almost non-invasive method of destroying cancer cells with high voltage electricity; and carbon nanotubes, which are already a popular way of repairing damaged tissues and might be used to regenerate nerves in the future. The aim of this article is to outline the potential uses of nanotechnology in medicine. Original articles and reviews have been used to present the new developments and directions of studies.


Subject(s)
Diagnostic Imaging , Nanomedicine/methods , Nanostructures/therapeutic use , Atherosclerosis/therapy , Humans , Neoplasms/diagnosis , Neoplasms/therapy
2.
Pol Merkur Lekarski ; 37(220): 248-52, 2014 Oct.
Article in Polish | MEDLINE | ID: mdl-25518584

ABSTRACT

Cannabinoids, psychoactive substances present in cannabis, have been known to mankind for hundreds of years. Apart from 9-tetrahydrocannabinol (THC) substances found in the cannabis herb with the highest toxicological value are cannabidiol (CBD) and cannabinol (CBN). The discovery of CB1 and CB2 receptors, located in various tissues (ranging from the brain to peripheral tissues), has defined the potential objective of these new chemical substances' effects. Many studies on the application of cannabinoids in the treatment of various diseases such as diabetes, neoplasms, inflammatory diseases, neurological conditions, pain and vomitting were conducted. Drugs containing e.g. THC appear on the pharmaceutical market. Substances affecting cannabinoid receptors may show beneficial effects, but they may also cause the risk of side effects related mainly to the inhibition of central nervous system. The purpose of this dissertation is the analysis, whether the substances responsible for the effects of marijuana, can find application in medicine. Original articles and reviews were used to summarize the results of studies connected to the topic.


Subject(s)
Cannabinoids/therapeutic use , Medical Marijuana/therapeutic use , Diabetes Mellitus/drug therapy , Dronabinol/therapeutic use , Humans , Neoplasms/drug therapy , Nervous System Diseases/drug therapy , Pain/drug therapy , Phytotherapy/methods , Receptors, Cannabinoid/drug effects , Vomiting/prevention & control
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