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1.
BMC Res Notes ; 12(1): 776, 2019 Nov 27.
Article in English | MEDLINE | ID: mdl-31775849

ABSTRACT

OBJECTIVE: Modern technologies are increasingly used in the development of cognitive interventions for older adults. Research into possible applications of virtual reality in such interventions has begun only recently. The aim of present study was to evaluate the effects of 8 sessions of VR-based cognitive training using the GRADYS game in healthy older adults (n = 72; aged 60-88) and older adults living with mild dementia (n = 27; aged 60-89). RESULTS: Older adults with mild dementia demonstrated worse baseline cognitive performance than participants without dementia. Both groups showed progress in training, which was greater in healthy older adults. There were also significant differences in cognitive functioning before and after the training. However, positive changes were revealed almost exclusively in the group of older adults without dementia. Based on the findings, we can recommend the GRADYS game for cognitive enhancement and as a possible counter-measure for cognitive decline experienced in normal cognitive ageing. Our results provide also support for the usefulness of VR technology in cognitive interventions in older adults. The use of the GRADYS game in persons living with dementia, however, would require several of the hardware and software modifications. Trial registration ISRCTN17613444, date of registration: 10.09.2019. Retrospectively registered.


Subject(s)
Cognition , Cognitive Dysfunction/psychology , High Fidelity Simulation Training , Virtual Reality , Aged , Aged, 80 and over , Cognitive Dysfunction/therapy , Cognitive Remediation/education , Dementia/therapy , Female , Humans , Male , Middle Aged , Neuropsychological Tests , Pilot Projects , Research Design , Retrospective Studies , Video Games
2.
Pol Przegl Chir ; 90(2): 5-9, 2018 Apr 30.
Article in English | MEDLINE | ID: mdl-29773764

ABSTRACT

Degloving injury poses a severe therapeutic challenge concerning both trauma and plastic surgery. The injury involves separation of skin and subcutaneous tissue from fascia and muscles. Treatment is often long-lasting and brings unsatisfying results due to the extent of damage, risk of infection and massive blood loss. In this article, we present the management and therapeutic outcomes of a patient admitted due to the degloving injury of the lower extremity caused by workplace accident. We described the complexity of treatment including surgical intervention as well as additional treatment, which combined brought good esthetic outcome.


Subject(s)
Degloving Injuries/surgery , Hyperbaric Oxygenation/methods , Leg Injuries/surgery , Occupational Injuries/surgery , Plastic Surgery Procedures/methods , Wound Healing/physiology , Adult , Debridement/methods , Female , Humans , Treatment Outcome
3.
Folia Med Cracov ; 57(1): 47-54, 2017.
Article in English | MEDLINE | ID: mdl-28608862

ABSTRACT

The study was carried out on 50 human lower legs obtained during autopsies (KBET: 122.6120.315.2016). The anatomy of the joint was studied using classical anatomical description methods. Based also on literature we have reviewed the current knowledge on the inferior tibiofibular joint blood supply considering the important clinically aspect - vascular density. Authors of this paper postulate relatively low vascular density of the region described and potential worse condition for healing in case of injury or after surgical procedures performed. We also postulate that ligament screws should be positioned with special respect to time limit which enables proper healing of the syndesmosis.


Subject(s)
Ankle Joint/pathology , Cartilage, Articular/pathology , Fibula/pathology , Ligaments, Articular/pathology , Tibia/pathology , Cadaver , Humans
4.
Folia Med Cracov ; 56(2): 37-43, 2016.
Article in English | MEDLINE | ID: mdl-28013320

ABSTRACT

Uterine leiomyomata present major problem for females. Although they are benign tumors their frequency is associated with many symptoms like infertility, abdominal pain, menorrhagia. Authors based on their own morphological studies and review of the literature try to indicate main factors causing angiogenesis within leiomyomata and its influence on tumor growth. The strongest proangiogenic factor seems to be hypoxia, which stimulates up- and down-regulation of numerous genetically determined substances. Also mechanical pressure acting upon newly growing vessels is one of the factors which may determine formation of so called "vascular pseudocapsule" around the lesion.


Subject(s)
Angiogenesis Inducing Agents/metabolism , Leiomyoma/blood supply , Myometrium/blood supply , Uterine Neoplasms/blood supply , Uterus/blood supply , Female , Humans , Intercellular Signaling Peptides and Proteins/metabolism , Neovascularization, Pathologic , Vascular Endothelial Growth Factors/metabolism
5.
Folia Med Cracov ; 56(1): 27-32, 2016.
Article in English | MEDLINE | ID: mdl-27513836

ABSTRACT

Angiogenesis is a process of development of new vessels from the preexisting vascular network of a host. This is process which is seen in many physiological situations but it accompanies also a development of different lesions, i.e. neoplasms. Uterine fibroids are one of the most frequent lesions which affect human internal female genital tracts. Authors briefly review most important pro-angiogenic factors, based on their own observation as well as reviewing current literature. They pay much attention to vascular density which is significantly changed in the uterine tumors.


Subject(s)
Angiogenesis Inducing Agents/metabolism , Leiomyoma/etiology , Myometrium/metabolism , Neovascularization, Pathologic , Uterine Neoplasms/etiology , Uterus/blood supply , Female , Humans , Intercellular Signaling Peptides and Proteins/metabolism , Vascular Endothelial Growth Factors/metabolism
6.
Folia Med Cracov ; 56(1): 33-47, 2016.
Article in English | MEDLINE | ID: mdl-27513837

ABSTRACT

Injuries of the lower leg are rather frequent in every day orthopedic routine. Process of healing takes quite a long time and is commonly dependent on the proper vasculature. e study was carried out on 50 human lower legs obtained during autopsies. The anatomy of the vascular system of the leg was studied using classical anatomical dissection methods. Based also on literature we have reviewed the current knowledge on the vascularization of the lower leg and its embryological background.


Subject(s)
Leg/anatomy & histology , Leg/blood supply , Muscle, Skeletal/anatomy & histology , Muscle, Skeletal/blood supply , Tibial Arteries/anatomy & histology , Autopsy , Humans , Skin/blood supply , Tibial Arteries/surgery
7.
Folia Med Cracov ; 56(3): 5-9, 2016.
Article in English | MEDLINE | ID: mdl-28275266

ABSTRACT

Anatomy of the vascular system of the leg was studied using classical anatomical dissection methods. Based also on literature we have reviewed the current knowledge on the vascularization of the lower leg and its embryological background with special respect toward the posterior tibial artery and its branches.


Subject(s)
Leg/anatomy & histology , Leg/blood supply , Muscle, Skeletal/anatomy & histology , Muscle, Skeletal/blood supply , Tibial Arteries/anatomy & histology , Autopsy , Humans , Skin/blood supply , Tibial Arteries/surgery
8.
Folia Med Cracov ; 55(4): 71-9, 2015.
Article in English | MEDLINE | ID: mdl-26867121

ABSTRACT

The study was carried out on 50 human lower legs obtained during autopsies. The anatomy of the joint was studied using classical anatomical description methods. Based also on literature we have reviewed the current knowledge on the inferior tibiofibular joint.


Subject(s)
Ankle Joint/anatomy & histology , Fibula/anatomy & histology , Tibia/anatomy & histology , Arthroscopy/methods , Autopsy , Female , Humans , Ligaments, Articular/anatomy & histology , Male
9.
Folia Med Cracov ; 55(4): 91-7, 2015.
Article in English | MEDLINE | ID: mdl-26867123

ABSTRACT

Corrosion casting and scanning electron microscopy are currently best available technique which allows observation of microvascular bed of different anatomical structures and obtaining quasi 3-D pictures, necessary for reconstruction of microvessels. Application of synthetic resins, which fill practically the whole vascular bed enables profound analysis of such obtained specimens.


Subject(s)
Blood Vessels/ultrastructure , Corrosion Casting/methods , Microscopy, Electron, Scanning/methods , Uterus/blood supply , Female , Humans , Microcirculation , Neovascularization, Pathologic/pathology , Uterus/physiology
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