[Pain control with paracetamol following inguinal herniorrhaphy or orchidopexy in childhood]. / Schmerztherapie nach Leistenbruch- und Leistenhodenoperationen mit Paracetamol im Kindesalter.

OBJECTIVE: The application of opiates after day case surgery in childhood is discussed controversially because of possible complications. Therefore many anaesthetists try to avoid these substances and prefer peripheral analgesics for postoperative pain control. METHODS: By distributing a questionnaire concerning the arguments connected with postoperative pain to 267 parents (a total of 78.3% of the questionnaires was returned) of children that had undergone inguinal herniorrhaphy or orchidopexy we hoped to gain insight into the judgement of peripheral analgesics-in this case acetaminophen-following inguinal herniorrhaphy or orchidopexy. During standardized anaesthesia the children received acetaminophen suppositories (15-20 mg/kg BW). After release from the hospital on the same day this drug was administered by the parents in case of necessity. RESULTS: Need for analgesics was significantly higher in the group of orchidopexy than in the group of herniorrhaphy (p < .01) and even memory of pain three days after the operation seemed to be higher in this group. The sleep patterns were more influenced by orchidopexy. Surprisingly 75% of the children following herniorrhaphy received no analgesics at all after release from the hospital (6 hours postoperatively). CONCLUSION: Following herniorrhaphy the postoperative pain therapy with acetaminophen seems to be sufficient. For the postoperative pain treatment after orchidopexy additional measures like local nerve blocks, regional anesthesia or wound infiltrations with local anaesthetics should be considered.

[Capnometry in pediatric anesthesia. The effect of the measurement site and respiratory rate]. / Kapnometrie in der Kinderanästhesie. Einfluss von Messort und Atemfrequenz.

OBJECTIVE: To evaluate the influences of site of measurement, respiratory rate, and tidal volume on end-tidal PCO2 measurement in children ventilated with a non-rebreathing system. SETTING: Paediatric surgical patients of a university hospital. PATIENTS: Thirty-one children scheduled for major abdominal or urogenital surgery; weight varying between 2.2 and 9.8 kg. INTERVENTIONS AND METHODS: During a relative steady-state situation, end-tidal carbon dioxide partial pressure (PetCO2) was measured at the proximal and distal ends of the endotracheal tube by a sidestream analyser (Datex, Normocap) and between the proximal end of the tube and the Y-piece of the ventilator by a mainstream analyser (Hewlett Packard, HP14265A). PetCO2 was corrected for water vapor and calculated as partial pressure at a barometric pressure of 760 mmHg. At the same time, capillary blood was taken for blood gas analysis. The capillary-end-tidal PCO2 gradient [dPCO2(cap-et)] was computed to compare the three capnometric methods. Statistical analysis was performed with the Friedmann test. Correlations were calculated by means of the least-square fitting method and significance of the correlation was checked with the F-test. RESULTS: dPCO2 (cap-et) did not differ significantly in children with more than 6 kg body weight. In patients less than 6 kg, however, the three capnometric methods revealed significantly different dPCO2 (cap-et) values (P less than 0.01): dPCO2 (cap-et) was 3.0 +/- 4.7 mmHg at the distal end of the endotracheal tube, 5.8 +/- 4.6 mmHg at the proximal end, and 8.7 +/- 4.6 mmHg between the proximal sidestream connector and the Y-piece of the ventilator. There was no correlation between tidal volume and dPCO2 (cap-et) (Fig. 1), however, a significant relation was found between respiratory rate and dPCO2 (cap-et) (Fig. 2) and between respiratory rate and the PCO2 difference between the distal and proximal ends of the endotracheal tube (Fig. 3). CONCLUSIONS: Even in a non-rebreathing system, capnometry is influenced by the site of measurement. In small children with body weight below 6 kg, analysis of an endotracheal sample may provide the best PetCO2 values. In our opinion, dPCO2 (cap-et) in the present investigation was not caused by rebreathing or by pendelluft (a significant correlation between dPCO2 (cap-et) and tidal volume would then have been expected), but was mainly due to ventilation-perfusion mismatch. This may result from high respiratory rates causing inadequate ventilation of lung regions with long time-constants.

Day case surgery in childhood from the parents' point of view.

294 parents whose children underwent day case surgery received a questionnaire covering the topics postoperative analgesia, memory of pain, sleep patterns and assessment of the time spent in the hospital. A total of 80.6% of the questionnaires were returned. We were not able to recognize any indications of behavioral disturbances, in particular disturbances of sleep. The need for analgesics was surprisingly low following release from the hospital. However, even on the third postoperative day 16.8% of the children still had unpleasant or strong memories of the pain they had experienced. Improvement in this area might be achieved by the application of nerve blocks, possibly in combination with analgesics. Further possibilities for improvement exist with premedication. The long waiting periods between hospital admittance and commencement of surgery were found to be very unpleasant. During surgery psychological counseling of the parents should be made possible.

Studies to be conducted before projected operations from the pediatric surgeon's point of view.

To rationally discuss the "need for preoperative laboratory investigations prior to performing an operation that can be pre-planned", two questions must be considered: 1. What kind of complications were encountered during or after 25,872 anesthesias performed in a 20-year period? 2. What kind of diseases were recognized only postoperatively which apparently could not be diagnosed preoperatively via case history and clinical examination? The results of these analyses are tabulated and assessed. It could be shown that the case history and the clinical examination of the patient on the day of surgery rank before all laboratory tests. With regard to peroperative respiratory disturbances it could be proven that children within the first trimester are particularly susceptible to such alterations. Furthermore, it could be demonstrated that within this group premature babies are more susceptible to this kind of complication than babies born at date. With regard to the incidence of preoperative respiratory disturbances in children with or without infection of the upper respiratory tract, it was shown that children without such symptoms who had however undergone an infection three to four weeks before the operation, were more susceptible to peroperative respiratory disturbances than children without any infection or even children suffering from an acute infection. Taking the physiological Hb decrease at the end of the first trimester as an example, questions on the optimal date for surgery are discussed. Preoperative handling is discussed on the basis of the blood glucose level of 500 children after a fasting period of 3-4 hours.

[Complaints in the postoperative phase related to anesthetics]. / Beschwerden in der postoperativen Phase in Abhängigkeit vom Narkosemittel.

In two prospective, randomized studies the frequency of headache, nausea, vomiting, and analgesic requirement during the first postoperative 24 h was observed in order to study differences between the sexes and the inhalation anesthetics halothane, enflurane, isoflurane, or balanced anesthesia with enflurane/alfentanil. Nausea and vomiting were more frequent after enflurane than after halothane or isoflurane. There was no significant difference between anesthetics and frequency of headache, but there were significant differences in postoperative analgesic requirements which were highest after halothane and lowest after isoflurane. Postoperative complaints were always significantly greater among women than among men. The second study indicated that balanced anesthesia did not reduce the analgesic requirement compared to enflurane without alfentanil, but lead to a higher incidence of vomiting. After premedication with flunitrazepam and atropine and combined with 70% N2O/30% O2, isoflurane was the most favorable anesthetic agent with regard to the parameters studied. Balanced anesthesia with enflurane/alfentanil did not show any advantages for patients in the postoperative phase under the given conditions.