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Pharmazie ; 35(12): 777, 1980 Dec.
Article in German | MEDLINE | ID: mdl-7208580

ABSTRACT

The liberation of glaucine hydrobromide from Tussiglauzin dragées has been verified. The release to artificial gastric juice was determined by three different procedures: method using the apparatus according to Grzesiczak, stationary-basket method and rotating-basket method. All three methods showed that the largest proportion of the drug (greater than 90%) is released within 2.5 h, the maximum amount determined by means of the rotating-basket method being 99.2%.


Subject(s)
Aporphines , Chemistry, Pharmaceutical , Diffusion , Kinetics , Tablets
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