ABSTRACT
Glomangiosarcoma, or malignant glomus tumor, is a very rare neoplasm that when seen typically arises from a benign glomus tumor. Despite having histologic features of malignancy, these tumors usually do not metastasize. However, when metastasis occurs this disease is often fatal. We report a case of a malignant glomus tumor arising de novo on the nose of an 89-year-old white woman, and we review the literature concerning glomangiosarcomas.
Subject(s)
Glomus Tumor/pathology , Nose Neoplasms/pathology , Skin Neoplasms/pathology , Aged , Aged, 80 and over , Female , Glomus Tumor/surgery , Humans , Mohs Surgery , Nose Neoplasms/surgery , Skin/pathology , Skin Neoplasms/surgeryABSTRACT
BACKGROUND: Mucoepidermoid carcinoma is a relatively common neoplasm of the major and minor salivary glands comprising 10-30% of primary carcinomas. They may involve the skin through direct extension, metastases, and rarely, as a primary focus (adenosquamous carcinoma). OBJECTIVE: To discuss through case reports, the nomenclature, histology, clinical course, and treatment of mucoepidermoid/adenosquamous carcinoma. METHODS: We present a case of mucoepidermoid carcinoma primary to an upper eyelid accessory lacrimal gland with direct cutaneous extension and a case of primary cutaneous adenosquamous carcinoma of the scalp. RESULTS: An eyelid neoplasm of lacrimal origin was initially treated with Mohs micrographic surgery (MMS), requiring an orbital exenteration to achieve a tumor-free plane. In the second case, a primary scalp lesion was cleared with MMS. Neither patient has had local recurrence or metastases. CONCLUSION: Correct diagnosis is crucial to pursuing adequate treatment for this aggressive neoplasm. We support the use of MMS to achieve local control.
Subject(s)
Carcinoma, Mucoepidermoid/pathology , Choristoma/pathology , Eyelid Neoplasms/pathology , Lacrimal Apparatus/pathology , Scalp/pathology , Skin Neoplasms/pathology , Aged , Aged, 80 and over , Carcinoma, Mucoepidermoid/surgery , Eyelid Neoplasms/surgery , Humans , Male , Middle Aged , Mohs Surgery , Neoplasm Invasiveness , Scalp/surgery , Skin Neoplasms/surgeryABSTRACT
Verrucous carcinoma of the oral cavity is relatively rare. Well-documented associations include human papillomavirus and carcinogens such as tobacco. Less well understood is the association with chronic inflammation, such as seen in lichen planus. Verrucous carcinoma has previously been described occurring in lesions of lichen planus of the foot and penis. We report the first case, to our knowledge, of verrucous carcinoma occurring in a lesion of oral lichen planus.
Subject(s)
Carcinoma, Verrucous/complications , Lichen Planus, Oral/complications , Mouth Neoplasms/complications , Aged , Carcinoma, Verrucous/pathology , Carcinoma, Verrucous/surgery , Female , Humans , Lichen Planus, Oral/pathology , Lichen Planus, Oral/surgery , Mohs Surgery , Mouth Neoplasms/pathology , Mouth Neoplasms/surgery , Neoplasm Recurrence, LocalABSTRACT
BACKGROUND: Eccrine porocarcinoma is a rare, locally aggressive, potentially fatal neoplasm. While wide local excision has traditionally been the treatment of choice, recurrences following excision are common. OBJECTIVE: The purpose of this study was to review the traditional treatments of eccrine porocarcinoma as well as to introduce Mohs micrographic surgery as an alternative to wide local excision. METHODS: We reviewed all cases of eccrine porocarcinoma seen at Emory University between 1985 and 1999. All cases were treated definitively with Mohs micrographic surgery. The clinical characteristics and outcome of each case are summarized. RESULTS: Five patients with eccrine porocarcinoma were treated with Mohs micrographic surgery. There have been no recurrences to date, with an average follow-up of 2.1 years (ranging from 5 months to 4 years). CONCLUSION: Follow-up of five patients supports the view that Mohs micrographic surgery may be an effective treatment for eccrine porocarcinoma.
Subject(s)
Acrospiroma/pathology , Acrospiroma/surgery , Mohs Surgery/methods , Sweat Gland Neoplasms/pathology , Sweat Gland Neoplasms/surgery , Acrospiroma/diagnosis , Adult , Aged , Biopsy, Needle , Female , Follow-Up Studies , Humans , Male , Middle Aged , Sweat Gland Neoplasms/diagnosis , Treatment OutcomeABSTRACT
Immunosuppressive therapy predisposes to the development of a variety of neoplasms. A 63-year-old man developed multiple eruptive epithelial tumors 15 years after renal transplantation. The tumors included what had been diagnosed as squamous cell carcinomas, Bowen's disease, and solitary and eruptive keratoacanthomas. In addition, he developed a large plaque studded with small nodules that had the histologic features of keratoacanthoma. To our knowledge, this is the first example of acquired eruptive keratoacanthoma forming a large plaque.
