ABSTRACT
Case report of a patient with a giant ovarian cyst. On the basis of literature data, surgery and histology problems, as well as oncological therapy are discussed.
Subject(s)
Cystadenocarcinoma, Mucinous/surgery , Ovarian Neoplasms/surgery , Chemotherapy, Adjuvant , Cystadenocarcinoma, Mucinous/drug therapy , Cystadenocarcinoma, Mucinous/pathology , Female , Humans , Middle Aged , Ovarian Neoplasms/drug therapy , Ovarian Neoplasms/pathologySubject(s)
Histiocytoma, Benign Fibrous/etiology , Neoplasms, Radiation-Induced/etiology , Radiotherapy, High-Energy/adverse effects , Thoracic Neoplasms/etiology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Breast Neoplasms/radiotherapy , Female , Histiocytoma, Benign Fibrous/drug therapy , Humans , Middle Aged , Thoracic Neoplasms/drug therapyABSTRACT
Extravasation of doxorubicin (DXR) from a dorsal hand vein is described. At 28 days following this event, high dermal concentrations of DXR were still present, not only at the injection site (1.7 X 10(-6) M X g-1) but also at a distance of 5 cm (0.4 X 10(-6) m X g-1. This long persistence of DXR in the skin necessitates ample excision of the skin following severe extravasation of the drug.
Subject(s)
Doxorubicin/adverse effects , Skin Ulcer/chemically induced , Adult , Doxorubicin/administration & dosage , Doxorubicin/analysis , Female , Humans , Injections, Intravenous/adverse effects , Necrosis/chemically induced , Skin Ulcer/metabolism , Time FactorsABSTRACT
A 25-year-old man presented with a malignant teratoma of the right testicle. After orchidectomy, the results of the surgical staging procedure were negative. Although pulmonary metastasis did not occur, massive bone marrow involvement with a bleeding tendency and hypercalcemic nephropathy developed. The response to chemotherapy was excellent, but after the attainment of a complete remission the patient developed carcinomatous leptomeningitis, which was confirmed at autopsy as cause of death.
