Fixation related shifts of perceptual localization counter to saccade direction.

Perisaccadic compression of the perceived location of flashed visual stimuli toward a saccade target occurs from about 50 ms before a saccade. Here we show that between 150 and 80 ms before a saccade, perceived locations are shifted toward the fixation point. To establish the cause of the "reverse" presaccadic perceptual distortion, participants completed several versions of a saccade task. After a cue to saccade, a probe bar stimulus was briefly presented within the saccade trajectory. In Experiment 1 participants made (a) overlap saccades with immediate return saccades, (b) overlap saccades, and (c) step saccades. In Experiment 2 participants made gap saccades in complete darkness. In Experiment 3 participants maintained fixation with the probe stimuli masked at various interstimulus intervals. Participants indicated the bar's location using a mouse cursor. In all conditions in Experiment 1 presaccadic compression was preceded by compression toward the initial fixation. In Experiment 2, saccadic compression was maintained but the preceding countercompression was not observed. Stimuli masked at fixation were not compressed. This suggests the two opposing compression effects are related to the act of executing an eye movement. They are also not caused by the requirement to make two sequential saccades ending at the initial fixation location and are not caused by continuous presence of the fixation markers. We propose that countercompression is related to fixation activity and is part of the sequence of motor preparations to execute a cued saccade.

Two sources of bias explain errors in facial age estimation.

Accurate age estimates underpin our everyday social interactions, the provision of age-restricted services and police investigations. Previous work suggests that these judgements are error-prone, but the processes giving rise to these errors are not understood. Here, we present the first systematic test of bias in age estimation using a large database of standardized passport images of heterogeneous ages (n = 3948). In three experiments, we tested a range of perceiver age groups (n = 84), and found average age estimation error to be approximately 8 years. We show that this error can be attributed to two separable sources of bias. First, and accounting for the vast majority of variance, our results show an assimilative serial dependency whereby estimates are systematically biased towards the age of the preceding face. Second, younger faces are generally perceived to be older than they are, and older faces to be younger. In combination, these biases account for around 95% of variance in age estimates. We conclude that perception of age is modulated by representations that encode both a viewer's recent and normative exposure to faces. The finding that age perception is subject to strong top-down influences based on our immediate experience has implications for our understanding of perceptual processes involved in face perception, and for improving accuracy of age estimation in important real-world tasks.

Attenuation of visual evoked responses to hand and saccade-initiated flashes.

Sensory attenuation refers to reduced brain responses to self-initiated sensations relative to those produced by the external world. It is a low-level process that may be linked to higher-level cognitive tasks such as reality monitoring. The phenomenon is often explained by prediction error mechanisms of universal applicability to sensory modality; however, it is most widely reported for auditory stimuli resulting from self-initiated hand movements. The present series of event-related potential (ERP) experiments explored the generalizability of sensory attenuation to the visual domain by exposing participants to flashes initiated by either their own button press or volitional saccade and comparing these conditions to identical, computer-initiated stimuli. The key results showed that the largest reduction of anterior visual N1 amplitude occurred for saccade-initiated flashes, while button press-initiated flashes evoked an intermediary response between the saccade-initiated and externally initiated conditions. This indicates that sensory attenuation occurs for visual stimuli and suggests that the degree of electrophysiological attenuation may relate to the causal likelihood of pairings between the type of motor action and the modality of its sensory response.

Attenuation of auditory evoked potentials for hand and eye-initiated sounds.

Reduction of auditory event-related potentials (ERPs) to self-initiated sounds has been considered evidence for a predictive model in which copies of motor commands suppress sensory representations of incoming stimuli. However, in studies which involve arbitrary auditory stimuli evoked by sensory-unspecific motor actions, learned associations may underlie ERP differences. Here, in a new paradigm, eye motor output generated auditory sensory input, a naïve action-sensation contingency. We measured the electroencephalogram (EEG) of 40 participants exposed to pure tones, which they produced with either a button-press or volitional saccade. We found that button-press-initiated stimuli evoked reduced amplitude compared to externally initiated stimuli for both the N1 and P2 ERP components, whereas saccade-initiated stimuli evoked intermediate attenuation at N1 and no reduction at P2. These results indicate that the motor-to-sensory mapping involved in speech production may be partly generalized to other contingencies, and that learned associations also contribute to the N1 attenuation effect.

Spatial compression: Dissociable effects at the time of saccades and blinks.

Various studies have identified systematic errors, such as spatial compression, when observers report the locations of objects displayed around the time of saccades. Localization errors also occur when holding spatial representations in visual working memory. Such errors, however, have not been examined in the context of eye blinks. In this study, we examined the effects of blinks and saccades when observers reproduced the locations of a set of briefly presented, randomly placed discs. Performance was compared with a fixation-only condition in which observers simply held these representations in working memory for the same duration; this allowed us to elucidate the relationship between the perceptual phenomena related to blinks, saccades, and visual working memory. Our results indicate that the same amount of spatial compression is experienced prior to a blink as is experienced in the control fixation-only condition, suggesting that blinks do not increase compression above that occurring from holding a spatial representation in visual memory. Saccades, however, tend to increase these compression effects and produce translational shifts both toward and away from saccade targets (depending on the time of the saccade onset in relation to the stimulus offset). A higher numerosity recall capacity was also observed when stimuli were presented prior to a blink in comparison with the other conditions. These findings reflect key differences underlying blinks and saccades in terms of spatial compression and translational shifts. Such results suggest that separate mechanisms maintain perceptual stability across these visual events.

Attentional bias modification facilitates attentional control mechanisms: evidence from eye tracking.

Social anxiety is thought to be maintained by biased attentional processing towards threatening information. Research has further shown that the experimental attenuation of this bias, through the implementation of attentional bias modification (ABM), may serve to reduce social anxiety vulnerability. However, the mechanisms underlying ABM remain unclear. The present study examined whether inhibitory attentional control was associated with ABM. A non-clinical sample of participants was randomly assigned to receive either ABM or a placebo task. To assess pre-post changes in attentional control, participants were additionally administered an emotional antisaccade task. ABM participants exhibited a subsequent shift in attentional bias away from threat as expected. ABM participants further showed a subsequent decrease in antisaccade cost, indicating a general facilitation of inhibitory attentional control. Mediational analysis revealed that the shift in attentional bias following ABM was independent to the change in attentional control. The findings suggest that the mechanisms of ABM are multifaceted.

Infant perceptual development for faces and spoken words: an integrated approach.

There are obvious differences between recognizing faces and recognizing spoken words or phonemes that might suggest development of each capability requires different skills. Recognizing faces and perceiving spoken language, however, are in key senses extremely similar endeavors. Both perceptual processes are based on richly variable, yet highly structured input from which the perceiver needs to extract categorically meaningful information. This similarity could be reflected in the perceptual narrowing that occurs within the first year of life in both domains. We take the position that the perceptual and neurocognitive processes by which face and speech recognition develop are based on a set of common principles. One common principle is the importance of systematic variability in the input as a source of information rather than noise. Experience of this variability leads to perceptual tuning to the critical properties that define individual faces or spoken words versus their membership in larger groupings of people and their language communities. We argue that parallels can be drawn directly between the principles responsible for the development of face and spoken language perception.

Determinants of motion response anisotropies in human early visual cortex: the role of configuration and eccentricity.

Anisotropies in the cortical representation of various stimulus parameters can reveal the fundamental mechanisms by which sensory properties are analysed and coded by the brain. One example is the preference for motion radial to the point of fixation (i.e. centripetal or centrifugal) exhibited in mammalian visual cortex. In two experiments, this study used functional magnetic resonance imaging (fMRI) to explore the determinants of these radial biases for motion in functionally-defined areas of human early visual cortex, and in particular their dependence upon eccentricity which has been indicated in recent reports. In one experiment, the cortical response to wide-field random dot kinematograms forming 16 different complex motion patterns (including centrifugal, centripetal, rotational and spiral motion) was measured. The response was analysed according to preferred eccentricity within four different eccentricity ranges. Response anisotropies were characterised by enhanced activity for centripetal or centrifugal patterns that changed systematically with eccentricity in visual areas V1-V3 and hV4 (but not V3A/B or V5/MT+). Responses evolved from a preference for centrifugal over centripetal patterns close to the fovea, to a preference for centripetal over centrifugal at the most peripheral region stimulated, in agreement with previous work. These effects were strongest in V2 and V3. In a second experiment, the stimuli were restricted to within narrow annuli either close to the fovea (0.75-1.88°) or further in the periphery (4.82-6.28°), in a way that preserved the local motion information available in the first experiment. In this configuration a preference for radial motion (centripetal or centrifugal) persisted but the dependence upon eccentricity disappeared. Again this was clearest in V2 and V3. A novel interpretation of the dependence upon eccentricity of motion anisotropies in early visual cortex is offered that takes into account the spatiotemporal "predictability" of the moving pattern. Such stimulus predictability, and its relationship to models of predictive coding, has found considerable support in recent years in accounting for a number of other perceptual and neural phenomena.

Biased saccadic responses to emotional stimuli in anxiety: an antisaccade study.

Research suggests that anxiety is maintained by an attentional bias to threat, and a growing base of evidence suggests that anxiety may additionally be associated with the deficient attentional processing of positive stimuli. The present study sought to examine whether such anxiety-linked attentional biases were associated with either stimulus driven or attentional control mechanisms of attentional selectivity. High and low trait anxious participants completed an emotional variant of an antisaccade task, in which they were required to prosaccade towards, or antisaccade away from a positive, neutral or threat stimulus, while eye movements were recorded. While low anxious participants were found to be slower to saccade in response to positive stimuli, irrespectively of whether a pro- or antisaccade was required, such a bias was absent in high anxious individuals. Analysis of erroneous antisaccades further revealed at trend level, that anxiety was associated with reduced peak velocity in response to threat. The findings suggest that anxiety is associated with the aberrant processing of positive stimuli, and greater compensatory efforts in the inhibition of threat. The findings further highlight the relevance of considering saccade peak velocity in the assessment of anxiety-linked attentional processing.

Human cortical and behavioral sensitivity to patterns of complex motion at eccentricity.

Complex patterns of image motion (contracting, expanding, rotating, and spiraling fields) are important in the coordination of visually guided behaviors. Whereas specialized detectors in monkey visual cortex show selectivity for particular patterns of complex motion, their representation in human visual cortex remains unclear. In the present study, functional magnetic resonance imaging (fMRI) was used to investigate the sensitivity of functionally defined regions of human visual cortex to parametrically modulated complex motion trajectories, coupled with complementary psychophysical testing. A unique stimulus design made it possible to disambiguate the neural responses and psychophysical sensitivity to complex motions per se from the distribution of local motions relative to the fovea, which are known to enhance cortical activity when presented radial to fixation. This involved presenting several small, separate motion fields in the periphery in a manner that distinguished them from global optic flow patterns. The patterns were morphed through complex motion space in a systematic time-locked fashion when presented in the scanner. Anisotropies were observed in the fMRI signal, marked by an enhanced response to expanding vs. contracting fields, even in early visual cortex. Anisotropies in the psychophysical sensitivity measures followed a similar pattern that was correlated with activity in areas hV4, V5/MT, and MST. This represents the first systematic examination of complex motion perception at both a behavioral and neural level in human observers. The characteristic processing anisotropy revealed in both data sets can inform models of complex motion processing, particularly with respect to computations performed in early visual cortex.

Implications of holistic face processing in autism and schizophrenia.

People with autism and schizophrenia have been shown to have a local bias in sensory processing and face recognition difficulties. A global or holistic processing strategy is known to be important when recognizing faces. Studies investigating face recognition in these populations are reviewed and show that holistic processing is employed despite lower overall performance in the tasks used. This implies that holistic processing is necessary but not sufficient for optimal face recognition and new avenues for research into face recognition based on network models of autism and schizophrenia are proposed.

Mismatch negativity/P3a complex in young people with psychiatric disorders: a cluster analysis.

BACKGROUND: We have recently shown that the event-related potential biomarkers, mismatch negativity (MMN) and P3a, are similarly impaired in young patients with schizophrenia- and affective-spectrum psychoses as well as those with bipolar disorder. A data driven approach may help to further elucidate novel patterns of MMN/P3a amplitudes that characterise distinct subgroups in patients with emerging psychiatric disorders. METHODS: Eighty seven outpatients (16 to 30 years) were assessed: 19 diagnosed with a depressive disorder; 26 with a bipolar disorder; and 42 with a psychotic disorder. The MMN/P3a complex was elicited using a two-tone passive auditory oddball paradigm with duration deviant tones. Hierarchical cluster analysis utilising frontal, central and temporal neurophysiological variables was conducted. RESULTS: Three clusters were determined: the 'globally impaired' cluster (n = 53) displayed reduced frontal and temporal MMN as well as reduced central P3a amplitudes; the 'largest frontal MMN' cluster (n = 17) were distinguished by increased frontal MMN amplitudes and the 'largest temporal MMN' cluster (n = 17) was characterised by increases in temporal MMN only. Notably, 55% of those in the globally impaired cluster were diagnosed with schizophrenia-spectrum disorder, whereas the three patient subgroups were equally represented in the remaining two clusters. The three cluster-groups did not differ in their current symptomatology; however, the globally impaired cluster was the most neuropsychologically impaired, compared with controls. CONCLUSIONS: These findings suggest that in emerging psychiatric disorders there are distinct MMN/P3a profiles of patient subgroups independent of current symptomatology. Schizophrenia-spectrum patients tended to show the most global impairments in this neurophysiological complex. Two other subgroups of patients were found to have neurophysiological profiles suggestive of quite different neurobiological (and hence, treatment) implications.

Perceptual adaptation helps us identify faces.

Adaptation is a fundamental property of perceptual processing. In low-level vision, it can calibrate perception to current inputs, increasing coding efficiency and enhancing discrimination around the adapted level. Adaptation also occurs in high-level vision, as illustrated by face aftereffects. However, the functional consequences of face adaptation remain uncertain. Here we investigated whether adaptation can enhance identification performance for faces from an adapted, relative to an unadapted, population. Five minutes of adaptation to an average Asian or Caucasian face reduced identification thresholds for faces from the adapted relative to the unadapted race. We replicated this interaction in two studies, using different participants, faces and adapting procedures. These results suggest that adaptation has a functional role in high-level, as well as low-level, visual processing. We suggest that adaptation to the average of a population may reduce responses to common properties shared by all members of the population, effectively orthogonalizing identity vectors in a multi-dimensional face space and freeing neural resources to code distinctive properties, which are useful for identification.

The relationship between saccadic suppression and perceptual stability.

Introspection makes it clear that we do not see the visual motion generated by our saccadic eye movements. We refer to the lack of awareness of the motion across the retina that is generated by a saccade as saccadic omission [1]: the visual stimulus generated by the saccade is omitted from our subjective awareness. In the laboratory, saccadic omission is often studied by investigating saccadic suppression, the reduction in visual sensitivity before and during a saccade (see Ross et al. [2] and Wurtz [3] for reviews). We investigated whether perceptual stability requires that a mechanism like saccadic suppression removes perisaccadic stimuli from visual processing to prevent their presumed harmful effect on perceptual stability [4, 5]. Our results show that a stimulus that undergoes saccadic omission can nevertheless generate a shape contrast illusion. This illusion can be generated when the inducer and test stimulus are separated in space and is therefore thought to be generated at a later stage of visual processing [6]. This shows that perceptual stability is attained without removing stimuli from processing and suggests a conceptually new view of perceptual stability in which perisaccadic stimuli are processed by the early visual system, but these signals are prevented from reaching awareness at a later stage of processing.

Orientation dependence of the orientation-contingent face aftereffect.

Prolonged exposure to upright and inverted female and male faces produces opposite effects on subsequent judgments of the sex of faces depending on their orientation. We show that the magnitude of this orientation-contingent gender aftereffect can be predicted from simple aftereffects induced separately at the same orientations. The contingent aftereffect can also be induced in faces tilted 90 degrees to the right and left, eliminating any difference in face-processing strategy that may be in operation with upright and inverted faces. This suggests that neurons employing a single face encoding strategy can be activated in an orientation-specific manner.

Orientation-contingent face aftereffects and implications for face-coding mechanisms.

Humans have an impressive ability to discriminate between faces despite their similarity as visual patterns. This expertise relies on configural coding of spatial relations between face features and/or holistic coding of overall facial structure. These expert face-coding mechanisms appear to be engaged most effectively by upright faces, with inverted faces engaging primarily feature-coding mechanisms. We show that opposite figural aftereffects can be induced simultaneously for upright and inverted faces, demonstrating that distinct neural populations code upright and inverted faces. This result also suggests that expert (upright) face-coding mechanisms can be selectively adapted. These aftereffects occur for judgments of face normality and face gender and are robust to changes in face size, ruling out adaptation of low-level, retinotopically organized coding mechanisms. Our results suggest a resolution of a paradox in the face recognition literature. Neuroimaging studies have found surprisingly little orientation selectivity in the fusiform face area (FFA) despite evidence that this region plays a role in expert face coding and that expert face-coding mechanisms are selectively engaged by upright faces. Our results, demonstrating orientation-contingent adaptation of face-coding mechanisms, suggest that the FFA's apparent lack of orientation selectivity may be an artifact of averaging across distinct populations within the FFA that respond to upright and inverted faces.

Perceptual grouping of biological motion promotes binocular rivalry.

Investigation of perceptual rivalry between conflicting stimuli presented one to each eye can further understanding of the neural underpinnings of conscious visual perception. During rivalry, visual awareness fluctuates between perceptions of the two stimuli. Here, we demonstrate that high-level perceptual grouping can promote rivalry between stimulus pairs that would otherwise be perceived as nonrivalrous. Perceptual grouping was generated with point-light walker stimuli that simulate human motion, visible only as lights placed on the joints. Although such walking figures are unrecognizable when stationary, recognition judgments as complex as gender and identity can accurately be made from animated displays, demonstrating the efficiency with which our visual system can group dynamic local signals into a globally coherent walking figure. We find that point-light walker stimuli presented one to each eye and in different colors and configurations results in strong rivalry. However, rivalry is minimal when the two walkers are split between the eyes or both presented to one eye. This pattern of results suggests that processing animated walker figures promotes rivalry between signals from the two eyes rather than between higher-level representations of the walkers. This leads us to hypothesize that awareness during binocular rivalry involves the integrated activity of high-level perceptual mechanisms in conjunction with lower-level ocular suppression modulated via cortical feedback.

Pulling faces: an investigation of the face-distortion aftereffect.

After adaptation to a face distorted to look unnaturally thin or fat, a normal face appears distorted in the opposite direction (Webster and MacLin 1999 Psychonomic Bulletin & Review 6 647-653). When the adapting face is oriented 45 degrees from vertically upright and the test face 45 degrees in the opposite direction, the axis of perceived distortion changes with the orientation of the face. The magnitude of this aftereffect shows a reduction of approximately 40% from that found when both adapting and test faces are tilted identically. This finding suggests that to a large degree the aftereffect is mediated not by low-level retinotopic (image-based) visual mechanisms but at a higher level of object-based processing. Aftereffects of a similar magnitude are obtained when adapting and test images are both either upright or inverted, or for an upright adapter and an inverted test; but aftereffects are smaller when the adapter is inverted and the test upright. This pattern of results suggests that the face-distortion aftereffect is mediated by object-processing mechanisms including, but not restricted to, configurational face-processing mechanisms.

Fitting the mind to the world: face adaptation and attractiveness aftereffects.

Average faces are attractive, but what is average depends on experience. We examined the effect of brief exposure to consistent facial distortions on what looks normal (average) and what looks attractive. Adaptation to a consistent distortion shifted what looked most normal, and what looked most attractive, toward that distortion. These normality and attractiveness aftereffects occurred when the adapting and test faces differed in orientation by 90 degrees (+45 degrees vs. -45 degrees ), suggesting adaptation of high-level neurons whose coding is not strictly retino- topic. Our results suggest that perceptual adaptation can rapidly recalibrate people's preferences to fit the faces they see. The results also suggest that average faces are attractive because of their central location in a distribution of faces (i.e., prototypicality), rather than because of any intrinsic appeal of particular physical characteristics. Recalibration of preferences may have important consequences, given the powerful effects of perceived attractiveness on person perception, mate choice, social interactions, and social outcomes for individuals.