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3.
J Toxicol Clin Toxicol ; 27(3): 173-82, 1989.
Article in English | MEDLINE | ID: mdl-2681811

ABSTRACT

Previous reports of lead foreign body (PbFB) ingestion by children include two cases of lead intoxication and two cases that resulted in death. It is generally accepted, however, that PbFB ingestion does not pose a risk of lead toxicity, provided that the PbFB is not retained in the gastrointestinal (GI) tract. Recent experience with two cases substantiates this belief. On separate occasions, two 9-year old girls ingested a PbFB. The first patient developed only mild, vague GI complaints. The highest reported blood lead level (BLL) was 15 mcg/dl. The second patient did not develop symptoms, and the highest reported BLL was 22 mcg/dl. Both patients passed the PbFB in the stool within two weeks. These cases suggest that PbFB ingestions can be treated in a manner similar to other uncomplicated foreign body ingestions.


Subject(s)
Digestive System , Foreign Bodies , Lead , Child , Female , Humans , Intestine, Small , Lead/blood , Lead Poisoning , Stomach
6.
7.
Ann Emerg Med ; 15(7): 797-804, 1986 Jul.
Article in English | MEDLINE | ID: mdl-3729101

ABSTRACT

To compare the relative central nervous system and cardiac toxicity of amoxapine, maprotiline, and trazodone with the older tricyclic antidepressants, a three-year (1981 through 1983) retrospective review was performed on 1,313 cases involving cyclic antidepressant exposures reported to the Maryland Poison Center. Seizures were more common in the amoxapine (24.5%) and maprotiline (12.2%) groups, compared with either the tricyclic antidepressants (3.0%) or trazodone (0%) (P less than .01). A higher incidence of seizures also was observed in desipramine ingestors (17.9%) compared with other tricyclic antidepressants. No significant differences in the incidence of central nervous system depression or cardiotoxicity was found between the groups. These findings support reports of an increased incidence of seizures in overdoses of amoxapine and maprotiline, but do not substantiate claims of less cardiotoxicity.


Subject(s)
Amoxapine/poisoning , Anthracenes/poisoning , Antidepressive Agents, Tricyclic/poisoning , Dibenzoxazepines/poisoning , Maprotiline/poisoning , Trazodone/poisoning , Adolescent , Adult , Aged , Arrhythmias, Cardiac/chemically induced , Central Nervous System Diseases/chemically induced , Child , Child, Preschool , Coma/chemically induced , Female , Humans , Male , Maryland , Middle Aged , Poison Control Centers , Retrospective Studies , Seizures/chemically induced , Tachycardia/chemically induced
8.
Am J Emerg Med ; 4(3): 259-61, 1986 May.
Article in English | MEDLINE | ID: mdl-3964368

ABSTRACT

Although the highly toxic nature of castor bean (Ricinus communis) is well recognized, reports of human toxicity in the English medical literature are scarce. The potentially lethal doses reported for children and adults are three beans and four to eight beans respectively. Recent experience with two cases provides added insight into the expected course of toxicity. In both cases, repeated vomiting, diarrhea, and transiently elevated serum creatinine occurred. Dehydration was much more pronounced in the second case. Both patients recovered uneventfully. Other reported manifestations of castor bean toxicity, such as hepatic necrosis, renal failure, erythrocyte hemolysis, convulsions, and shock, did not occur.


Subject(s)
Diarrhea/etiology , Plant Poisoning/therapy , Plants, Toxic , Ricinus communis , Ricinus , Vomiting/etiology , Adult , Aged , Creatinine/blood , Female , Humans , Male , Monitoring, Physiologic
9.
Ann Emerg Med ; 13(12): 1152-4, 1984 Dec.
Article in English | MEDLINE | ID: mdl-6150669

ABSTRACT

An elderly patient experienced an intracerebral bleed temporally related to the administration of syrup of ipecac. The experience of the certified regional poison centers of the American Association of Poison Control Centers shows that this is an uncommon event. The use and safety of ipecac in the elderly has not been adequately addressed in the past.


Subject(s)
Aged , Cerebral Hemorrhage/chemically induced , Ipecac/adverse effects , Adult , Female , Humans , Infant , Maryland , Middle Aged , Poison Control Centers , Retrospective Studies
11.
J Toxicol Clin Toxicol ; 22(5): 485-92, 1984.
Article in English | MEDLINE | ID: mdl-6397597

ABSTRACT

Two cases of subcutaneously administered hydrocarbon based products are presented and the literature reviewed. The toxicity associated with subcutaneous administration is limited to the site of injection producing cellulitis and sterile abscess formation. Management is discussed with emphasis on the importance of incision and drainage of developing abscesses. Perceived toxicity and ready availability of these products suggests that similar exposures can be expected.


Subject(s)
Insecticides/poisoning , Turpentine/poisoning , Abscess/chemically induced , Abscess/therapy , Adolescent , Adult , Cellulitis/chemically induced , Cellulitis/therapy , Drainage , Humans , Injections, Intravenous , Injections, Subcutaneous , Male , Suicide, Attempted
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