Early Elevation and Normalization of Electrode Impedance in Patients With Enlarged Vestibular Aqueduct Undergoing Cochlear Implantation.

OBJECTIVE: To characterize early changes in impedance in patients undergoing cochlear implantation with and without enlarged vestibular aqueducts (EVA). METHODS: Case-control retrospective study of patients undergoing cochlear implantation with and without EVA. Impedance was measured across all channels intraoperatively and within 24 hours of surgery. All patients received the same electrode array. RESULTS: Ten patients with EVA (and matched controls were identified). The average intraoperative impedance across all electrodes was significantly higher in patients with EVA (13.1 ±â€Š1.4 kΩ) than in controls (9.6 ±â€Š2.5 kΩ, p  < 0.001). At 24-hour activation, the average impedance across all electrodes was roughly equal in both groups (6.8 ±â€Š2.7 kΩ versus 6.5 ±â€Š2.1 kΩ, p  = 0.72). CONCLUSIONS: This study is the first identify differences in intraoperative impedance between patients with and without EVA. In addition, these data demonstrate rapid normalization within 24 hours of surgery. Such findings can give a window of insight into both the intracochlear microenvironment of patients with EVA and the important early electrode-fluid-tissue interface changes that occur within hours of surgery for all patients.

Evolution of impedance values in cochlear implant patients after early switch-on.

Cochlear implantation is currently the most effective treatment modality for severe to profound sensorineural hearing loss. Over the past few years, at the Department of Otolaryngology, Cheng Hsin General Hospital (Taipei, Taiwan), cochlear implant devices have been switched on within 24 hours of their implantation. Differences in impedance evolution after early switch-on for different devices have not been previously discussed. The present study aimed to investigate the impedance evolution of one device and the factors influencing this after early activation. Results are compared to published results of other devices. A total of 16 patients who received Advanced BionicsTM devices and had early activation within 24 hours of implantation, were included in the study. Impedance telemetry was recorded intraoperatively and postoperatively at 1 day, 1 week, 2 weeks, 4 weeks and 8 weeks. A stepwise increase was observed in the impedance evolution. To the best of our knowledge, the present study is the first to investigate the impedance evolution of the different devices after early switch-on within 24 hours of implantation and its influencing factors. Further research with a longitudinal design to compare the differences in electrode impedances between patients activated early versus those activated after a few weeks will be necessary for the disclosure of the underlying mechanisms.

Trends in Positioning for Robotic Prostatectomy: Results From a Survey of the Endourological Society.

PURPOSE: most robot-assisted laparoscopic prostatectomies (RALP) are performed with the patient in lithotomy, carrying risks of positioning-related complications. Newer robot models have allowed for supine positioning, potentially avoiding these pitfalls. We gauged the current sentiment on patient positioning among surgeons who perform robot-assisted surgery. METHODS: we surveyed members of the Endourological Society regarding their practice settings and their opinions on positioning for robot-assisted laparoscopic prostatectomy. Summary statistics were reviewed and data were analyzed using chi-square tests and t-tests. RESULTS: our survey had 92 eligible respondents. The majority were fellowship-trained, with 51% trained in robotics and 57% practicing in the U.S. with a mean of 13 years of practice. Most were working in an academic setting (69%) and performing at least 25 robotic prostatectomies yearly. 28 respondents used the Intuitive Surgical Inc. da Vinci® Xi™ exclusively (30%), and nearly two-thirds used it sometimes. Although 54% of respondents considered using supine positioning, less than half of these surgeons used it regularly, while 75% overall preferred lithotomy. A majority attributed this choice to surgical team familiarity with lithotomy positioning. Surgeons in the U.S. and those using the da Vinci® Xi™ were more likely to consider supine positioning. CONCLUSIONS: lithotomy position is the standard for RALP procedures; nonetheless, it poses significant risks that might be avoided with supine positioning. Our survey suggests that, although supine positioning has been considered, it has not gained momentum in practice. Addressing factors of inertia in training practices and one's surgical team might allow for novel and safer approaches.

Osteoporosis and Periodontitis.

Osteoporosis and periodontitis are both diseases characterized by bone resorption. Osteoporosis features systemic degenerative bone loss that leads to loss of skeletal cancellous microstructure and subsequent fracture, whereas periodontitis involves local inflammatory bone loss, following an infectious breach of the alveolar cortical bone, and it may result in tooth loss. Most cross-sectional studies have confirmed the association of osteoporosis and periodontitis primarily on radiographic measurements and to a lesser degree on clinical parameters. Multiple shared risk factors include age, genetics, hormonal change, smoking, as well as calcium and vitamin D deficiency. Both diseases could also be risk factors for each other and have a mutual impact that requires concomitant management. Suggested mechanisms underlying the linkage are disruption of the homeostasis concerning bone remodeling, hormonal balance, and inflammation resolution. A mutual interventional approach is emerging with complex treatment interactions. Prevention and management of both diseases require interdisciplinary approaches and warrants future well-controlled longitudinal and interventional studies for evidence-based clinical guidelines.