MR-guided radiofrequency ablation for treatment of hypovascular primary liver cancer / 中国介入影像与治疗学

Objective: To investigate the efficacy and safety of MR-guided radiofrequency ablation (RFA) for treatment of hypovascular primary liver cancer. Methods: Totally 21 patients with hypovascular primary liver cancer underwent RFA under guidance of 3.0T MR using MR compatible multipolar RF electrode. Immediate MRI evaluation of the ablated lesions and complications after RFA were performed. One month after operation, plain and dynamic enhanced MR scan of liver were performed, and then reexamination was done every 2-3 months until June 2018. The recurrence rate was observed. Results: A total of 29 lesions were completely ablated among 21 patients assessing by immediate imaging. Complications such as low heart rate, pain and minor hemorrhage etc. occurred in 15 patients (15/21, 71.43%). The follow-up period was 6-26 months (mean [10.23±4.26] months). Local recurrence of ablated lesions was observed in 2 patients (2/21, 9.52%). Conclusion: MR-guided RFA for treatment of hypovascular primary liver cancer is safe and effective with low recurrence rate, which could potentially be applied in clinical practices.

The investigation of demographic characteristics and the health-related quality of life in patients with diabetic foot ulcers at first presentation.

To investigate the characteristics of diabetic patients with foot ulcers, their health-related quality of life (HRQoL), and the link between them. The study population included 131 consecutive patients presenting in a diabetic foot clinic with a new foot ulcer between December 1, 2011, and May 1, 2012. The authors collected sociodemographic data, foot and ulcer characteristics using the Wagner Grade, and HRQoL (using the SF-36 Scale) information; 54.2% of the patients were in Wagner 2 or Wagner 3 categories. In all the 8 SF-36 subscales and in the SF-36 summary scales, the patients with diabetic foot ulcer had significantly poorer HRQoL than the general population in China (P < .01). Their Wagner Grade had negative correlation with all the SF-36 subscales and the summary scales (P < .05). In conclusion, new diabetic foot ulcers were already in poor condition when patients first visited the diabetic foot clinic. Concomitantly, patients had worse HRQoL compared with the general population. More effective interventions are needed to improve their self-care level and HRQoL.

The Observation On Curative Effect Of Qingkailing Injection In Treating Diabetic Foot With Ischemic Gangrene In early Stage / 医学研究杂志

Objective To observe the curative effect of Qingkailing Injection in treating diabetic foot with ischemic gangrene in early stage and investigate it′s therapeutic mechanism.Methods 40 patients were divided into Qingkailing treatment group (treatment group) and Xuesetong treatment group (controlled group),4 weeks in a treatment course.The foot skin color,skin temperature,degree of tumefaction,rage of gangrene,ability of walking,degree of pain were observed and C-reactive protein (CRP),fibrinogen (Fib) in plasma were detected before and after the treatment respectively.Results After 4 weeks treatment by Qingkailing Injection,the various standards mentioned above in treatment group were improved obviously,Compared with treatment group (except Fib),There was remarkable significance by statistics (P