1.
Oncotarget
; 9(40): 25826-25832, 2018 May 25.
Article
in English
| MEDLINE
| ID: mdl-29899824
ABSTRACT
We have developed a clinically validated NGS assay that includes tumor, germline and RNA sequencing. We apply this assay to clinical specimens and cell lines, and we demonstrate a clinical sensitivity of 98.4% and positive predictive value of 100% for the clinically actionable variants measured by the assay. We also demonstrate highly accurate copy number measurements and gene rearrangement identification.