ABSTRACT
A hospital outbreak, traced to a case of Norwegian scabies, resulted in 45 and 32 symptomatic cases in staff and patients, respectively. A total of 228 asymptomatic in-patient contacts and over 500 staff required prophylactic treatment with either 1% gamma benzene hexachloride lotion or 5% permethrin cream. Recurrences occurred in seven staff members and five patients. The outbreak was contained within four months.
Subject(s)
Cross Infection/prevention & control , Disease Outbreaks , Infection Control/methods , Occupational Diseases/prevention & control , Scabies/prevention & control , Aged , Aged, 80 and over , Cross Infection/epidemiology , Cross Infection/transmission , Female , Humans , Occupational Diseases/epidemiology , Personnel, Hospital , Scabies/epidemiology , Scabies/transmissionABSTRACT
Clinical experience with five patients exposed to phosgene is described. The treatment of phosgene poisoning was focused upon the presenting problem, pulmonary edema. Arterial hypoxemia was treated with a face mask with 10 cm CPAP with the FiO2 adjusted as needed or with a volume ventilator with controlled ventilation. Ventilation was controlled to reduce the work of breathing. Metabolic acidosis was treated with NaCHO3 to produce a normal pH. A vigorous program of diuresis was used to treat the pulmonary edema. Lasix was administered to produce a negative fluid balance while maintaining a good urinary output. The negative fluid balance correlated well with reduced oxygen requirements.
Subject(s)
Phosgene/poisoning , Pulmonary Edema/chemically induced , Acid-Base Imbalance/drug therapy , Acid-Base Imbalance/etiology , Adult , Bicarbonates/therapeutic use , Combined Modality Therapy , Furosemide/therapeutic use , Humans , Hypoxia/etiology , Hypoxia/therapy , Laryngeal Edema/chemically induced , Male , Occupational Diseases/chemically induced , Occupational Diseases/therapy , Oxygen Inhalation Therapy , Pulmonary Edema/complications , Pulmonary Edema/therapy , Sodium/therapeutic use , Sodium BicarbonateABSTRACT
An infectious bronchitis virus, designated G48, isolated from birds during an outbreak of nephritis in a previously vaccinated broiler flock, overcame the resistance induced in birds vaccinated with 2 commercially available vaccines. Birds vaccinated with the A isolate of infectious bronchitis resisted challenge with this new virus. Cross neutralisation studies revealed that the new virus was serologically distinct from the 4 viruses tested. Homologous antiserum to G48 did not neutralise the other viruses and only antiserum to the A virus completely neutralised the new virus.
