1.
Org Lett
; 16(22): 5940-3, 2014 Nov 21.
Article
in English
| MEDLINE
| ID: mdl-25383747
ABSTRACT
A highly efficient Pt-catalyzed [3,3] sigmatropic rearrangement/cyclization cascade of N-propargylhydrazones is reported. The process provides expedient access to a variety of highly functionalized pyrazoles. The substrate has good substituted group compatibility, and the bioactive 3-CF3 pyrazoles could be synthesized easily with this method.