Accuracy of implant height and width measurement with triaxial rotation method based on cone-beam CT.

Objective: To investigate the accuracy of implant height and width measurement in the mandibular and maxillary first molar region based on cone-beam CT (CBCT) data, and to establish an accurate method for bone measurement in the implant region. Materials and methods: CBCT images of 122 patients with implant in mandibular or maxillary first molar region were retrospectively collected. Two methods were used to measure sagittal height (SH), coronal height (CH), sagittal width (SW), and coronal width (CW) of implants. Method 1 (general method): the images were analyzed using the built-in software NNT 9.0 software. SHl, CHl, SWl, and CWl were measured on the reconstructed sagittal and coronal based on the radiologist's own experience. Method 2 (triaxial rotation method): the raw data were demonstrated in Expert mode of NNT 9.0 software, in which the coronal axis and sagittal axis were rotated paralleling to the long axis of the implant for reconstruction, and then SH2, CH2, SW2, and CW2 were measured on the reconstructed sagittal and coronal images. The results of two methods were compared with the actual implant size (H0, W0). Paired T-test was performed for statistical analysis. Dahlberg formula was used to check the measurement error. Results: For method 1, there was no significant differences between SHl and H0 (P > 0.05), but significant differences between CHl and H0, SWl and W0, and CWl and W0 (P < 0.05). For method 2, there were no significant differences between all measurements and actual size (P > 0.05). The random error range measured using Dahlberg formula was 0.157-1.171 mm for general method and 0.017-0.05 mm for triaxial rotation method. Conclusion: The triaxial rotation method is accurate for implant height and width measurements on CBCT images and could be used in pre-operatively bone height and width measurement of potential implant sites.

Exploring the potential of ChatGPT as an adjunct for generating diagnosis based on chief complaint and cone beam CT radiologic findings.

AIM: This study aimed to assess the performance of OpenAI's ChatGPT in generating diagnosis based on chief complaint and cone beam computed tomography (CBCT) radiologic findings. MATERIALS AND METHODS: 102 CBCT reports (48 with dental diseases (DD) and 54 with neoplastic/cystic diseases (N/CD)) were collected. ChatGPT was provided with chief complaint and CBCT radiologic findings. Diagnostic outputs from ChatGPT were scored based on five-point Likert scale. For diagnosis accuracy, the scoring was based on the accuracy of chief complaint related diagnosis and chief complaint unrelated diagnoses (1-5 points); for diagnosis completeness, the scoring was based on how many accurate diagnoses included in ChatGPT's output for one case (1-5 points); for text quality, the scoring was based on how many text errors included in ChatGPT's output for one case (1-5 points). For 54 N/CD cases, the consistence of the diagnosis generated by ChatGPT with pathological diagnosis was also calculated. The constitution of text errors in ChatGPT's outputs was evaluated. RESULTS: After subjective ratings by expert reviewers on a five-point Likert scale, the final score of diagnosis accuracy, diagnosis completeness and text quality of ChatGPT was 3.7, 4.5 and 4.6 for the 102 cases. For diagnostic accuracy, it performed significantly better on N/CD (3.8/5) compared to DD (3.6/5). For 54 N/CD cases, 21(38.9%) cases have first diagnosis completely consistent with pathological diagnosis. No text errors were observed in 88.7% of all the 390 text items. CONCLUSION: ChatGPT showed potential in generating radiographic diagnosis based on chief complaint and radiologic findings. However, the performance of ChatGPT varied with task complexity, necessitating professional oversight due to a certain error rate.

Epidemiological and CBCT characterizations of odontomas: A retrospective study of 87,590 subjects.

OBJECTIVES: This study aimed to assess the epidemiological and three-dimensional (3D) radiological characterizations of odontomas, as well as the spatial relationship between odontomas and gubernaculum tracts (GT). MATERIALS AND METHODS: We retrieved the cone-beam computed tomography (CBCT) data of 87,590 patients. Dentition, location, type, diameter of the odontomas, width of the dental follicle (DF), the spatial relationship between the odontoma and GT, and the influence on adjacent teeth were evaluated. RESULTS: Significant differences were found in age, dentition, location, Max/Min diameter, width of DF, impaction, retention, and root bending of adjacent teeth among different spatial relationships between the odontoma and GT (all p < 0.05), as well as in age, type and size, absence, impaction, malposition, and retention of adjacent teeth among different locations of odontomas (all p < 0.05). Compared to the odontomas without impaction, those with impaction had larger diameter (p < 0.05 in all directions). This statistically significant association was consistent for odontomas with malposition, while no similar result was observed in the maximum diameter. CONCLUSION: Our findings provide the preliminary data for clinicians to comprehensively understand the incidence, radiographic characterizations and symptoms of odontoma in Chinese population.

Morphological changes of the root apex in anterior teeth with periapical periodontitis: an in-vivo study.

INTRODUCTION: The aim was to analyze the morphological changes of root apex in anterior teeth with periapical periodontitis. METHODS: 32 untreated anterior teeth with periapical periodontitis were enrolled, compared with the healthy contralateral teeth. Two-dimensional measurement of Cone-beam computed tomography was used to determine the location and measure diameter of the apical constriction according to Schell's methods. An open-source software (3D Slicer) was used to reconstruct the teeth. The apical constriction form was analysis according to Schell's topography. The distances of apical constriction to apical foramen and anatomical apex were measured respectively. RESULTS: The difference value between buccolingual and mesiodistal diameter was (0.06 ± 0.09) mm and (0.04 ± 0.04) mm in periapical periodontitis and controls (p < 0.05). The mean distance between apical constriction and anatomical apex was significantly shorter in periapical periodontitis than controls, so was the mean distance of apical constriction to apical foramen. The most common form of apical constriction was flaring (65.6%) in periapical periodontitis. CONCLUSIONS: The anterior teeth with periapical periodontitis had shorter distances of apical constriction to anatomical apex and apical foramen, bigger disparities between the diameters of buccolingual and mesiodistal, and higher proportion of flaring apical constriction.

Could cone-beam computed tomography demonstrate the lateral accessory canals?

BACKGROUND: Recently, using cone-beam computed tomography (CBCT) to assess root canal morphology has become popular; however, few studies have examined its efficiency to assess the entire root canals, including the tiny lateral and accessory canals (LACs). This study aimed to assess the ability of CBCT to evaluate the root canal of mandibular incisors at three different scanning settings, compared with the canal staining and tooth clearing (CS) technique as the gold standard. METHODS: CBCT images of 70 extracted mandibular incisors were taken using NewTom VG CBCT at high-resolution scan mode (HZ), zoom scan mode (ZS), and full scan mode (FS), with different scanning settings. A radiologist, a postgraduate student, and an endodontist assessed the root canal morphology in a blinded manner. The number of root canals (NC), canal configuration according to Vertucci's classification (VC), and LACs were evaluated twice by each evaluator using the CBCT images, in comparison with CS. Comparisons of the differences were used the chi-square test, and the intra-evaluator and inter-evaluator agreement were used the Kappa statistics; the significance level was set at 0.05. RESULTS: The voxel dimension of HZ, ZS and FS modes were 0.125 mm, 0.20 mm and 0.25 mm respectively, and the HZ mode had significant increased scanning doses. For NC, the diagnostic accuracy was >90% in all three modes, with no significant difference among the evaluators and modes. VC and LAC could only be evaluated in HZ mode. For VC, the accuracies were 97.1%, 94.3%, and 92.9% respectively, with no significant differences among the three evaluators. For LAC, the accuracies were 80.0%, 13.3%, and 33.3% respectively, and there were significant differences among the three evaluators. Intra-evaluator agreement was excellent, with the kappa values indicating "perfect" to "substantial" agreement. Inter-evaluator agreement was excellent for NC and VC; however, Kappa values could not be analyzed due to LACs detected were so variable. CONCLUSIONS: As far as possible, the HZ mode should be chosen to demonstrate the root canal system, and partial LACs could be detected using this mode; however, the potential benefit of the diagnostic information must be weighed against the increased radiation dose.

[Comparative study of root canal morphology of mandibular incisors by cone-beam CT and canal staining and clearing technique].

PURPOSE: To compare the root canal morphology of mandibular incisors by using cone-beam CT (CBCT) and canal staining and clearing technique. METHODS: Sixty-one extracted mandibular incisors with complete dental root and apex which received no endodontic treatment and no post crown restoration were selected. Each tooth was radiographed with CBCT, and the root canal system was stained by canal staining and clearing technique. The consistency of the number of root canal, root canal Vertucci type of mandibular permanent incisors between the two methods were compared, and the differences of the detection rate on root canal branch structure between the two methods were analyzed. The results were statistically analyzed with SPSS 17.0 software package. RESULTS: The Kappa value of single and double root canal types between CBCT and canal staining and clearing technique was 0.847 (P<0.001). The Kappa value of Vertucci root canal types between CBCT and canal staining and clearing technique was 0.861 (P<0.001). The detection rates of root canal branch structure were 8.19% and 22.95%, respectively, with significant difference between the two methods (P=0.025). The canal staining and clearing technique was significantly better than CBCT in detection of root canal branch structure. CONCLUSIONS: CBCT can reflect the root canal types nearly perfectly, but inferior to canal staining and clearing technique in detection of root canal branch structure, CBCT is a relatively accurate clinical diagnosis tool of root canal morphology.

Soft tissue recurrent ameloblastomas also show some malignant features: a clinicopathological study of a 15-year database

BACKGROUND: To investigate the clinicopathological features of six cases of soft tissue recurrent ameloblastoma and explore the role of increased aggressive biological behavior in the recurrences and treatment of this type of ameloblastomas. MATERIAL AND METHODS: In this study, we retrospectively reviewed recurrent ameloblastomas during a 15-year period; six cases were diagnosed as soft tissue recurrent ameloblastoma. The clinical, radiographic, cytological and immunohistochemical records of these six cases were investigated and analyzed. RESULTS: All the six soft tissue recurrent ameloblastomas occurred after radical bone resection, and were located in the adjacent soft tissues around the osteotomy regions. In Case 4, the patient developed pulmonary metastasis, extensive skull-base infiltration and cytological malignancy after multiple recurrences and malignant transformation was diagnosed. In the other five cases, although there were no cytological signs are sufficient to justify an ameloblastoma as malignant, some malignant features were observed. In Case 1, the tumor showed moderate atypical hyperplasia and the Ki-67 staining percentage was 40% positive, which are strongly suggestive of potential malignance. In Case 5, the patient developed a second soft tissue recurrence in the parapharyngeal region and later died of tumor-related complications. All the remaining three patients showed cytology atypia of varying degrees and high expression of PCNA or Ki-67, which confirmed active cell proliferation. CONCLUSIONS: Increased aggressiveness is an important factor of soft tissue recurrence. An intraoperative rapid pathological examination and more radical treatment are suggested for these cases

Soft tissue recurrent ameloblastomas also show some malignant features: A clinicopathological study of a 15-year database.

BACKGROUND: To investigate the clinicopathological features of six cases of soft tissue recurrent ameloblastoma and explore the role of increased aggressive biological behavior in the recurrences and treatment of this type of ameloblastomas. MATERIAL AND METHODS: In this study, we retrospectively reviewed recurrent ameloblastomas during a 15-year period; six cases were diagnosed as soft tissue recurrent ameloblastoma. The clinical, radiographic, cytological and immunohistochemical records of these six cases were investigated and analyzed. RESULTS: All the six soft tissue recurrent ameloblastomas occurred after radical bone resection, and were located in the adjacent soft tissues around the osteotomy regions. In Case 4, the patient developed pulmonary metastasis, extensive skull-base infiltration and cytological malignancy after multiple recurrences and malignant transformation was diagnosed. In the other five cases, although there were no cytological signs are sufficient to justify an ameloblastoma as malignant, some malignant features were observed. In Case 1, the tumor showed moderate atypical hyperplasia and the Ki-67 staining percentage was 40% positive, which are strongly suggestive of potential malignance. In Case 5, the patient developed a second soft tissue recurrence in the parapharyngeal region and later died of tumor-related complications. All the remaining three patients showed cytology atypia of varying degrees and high expression of PCNA or Ki-67, which confirmed active cell proliferation. CONCLUSIONS: Increased aggressiveness is an important factor of soft tissue recurrence. An intraoperative rapid pathological examination and more radical treatment are suggested for these cases.

Use of CBCT to investigate the root canal morphology of mandibular incisors.

PURPOSE: To investigate the root canal morphology of mandibular incisors using cone-beam computed tomography (CBCT). MATERIALS AND METHODS: A total of 353 patients with 1,412 healthy, well-developed mandibular incisors were enrolled. Radiographic examination by CBCT was conducted as part of their routine examination, diagnosis and treatment planning. The following observations were made using CBCT: (1) the number of roots; (2) the number of canals; (3) canal configuration according to Vertucci's classification; (4) the position of root canal bifurcations. RESULTS: Two canals were found in 10.9 % of mandibular central incisors, 25.5 % of lateral incisors and in 18.2 % of all the 1,412 mandibular incisors. Significantly, more lateral incisors possessed two canals than central incisors (p < 0.05). Of the teeth with two canals, type III incisors were the most prevalent, followed by types II, IV and V. Furthermore, 37.7 % of teeth were found to have root canal bifurcations that were at or near to the cortical-middle third junction regions of the roots. CONCLUSION: Routine mode CBCT imaging was clinically useful for detection of two canals and determines the position of root canal bifurcations in mandibular incisors.