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15.
Br Med J ; 2(5816): 743-4, 1972 Jun 24.
Article in English | MEDLINE | ID: mdl-4556543

ABSTRACT

A double-blind trial was performed in 60 women to establish the effectiveness of an ergot alkaloid, 2-Br-alpha-ergocryptine (ergocryptine; CB 154), in suppressing puerperal lactation and to compare it with stilboestrol and a placebo. At the doses selected ergocryptine and stilboestrol were equally effective.


Subject(s)
Ergot Alkaloids/pharmacology , Lactation/drug effects , Postpartum Period , Breast/drug effects , Clinical Trials as Topic , Diethylstilbestrol/administration & dosage , Diethylstilbestrol/pharmacology , Dosage Forms , Ergot Alkaloids/administration & dosage , Female , Follow-Up Studies , Humans , Placebos , Pregnancy
18.
Br Med J ; 3(5768): 228-9, 1971 Jul 24.
Article in English | MEDLINE | ID: mdl-5105219

ABSTRACT

Three patients suffering from non-puerperal galactorrhoea over periods ranging from two months to six years were treated with an ergot alkaloid, 2-Br-alpha-ergocryptine (CB 154). In all three cases the galactorrhoea was terminated. The apparent prolactin antagonism exhibited by this compound is discussed.


Subject(s)
Ergot Alkaloids/therapeutic use , Lactation Disorders/drug therapy , Adult , Ergot Alkaloids/adverse effects , Female , Humans , Lactation Disorders/etiology , Pituitary Neoplasms/complications , Pregnancy , Prolactin/antagonists & inhibitors
19.
Schweiz Z Gynakol Geburtshilfe ; 2(4-6): 485-9, 1971.
Article in German | MEDLINE | ID: mdl-12256527

ABSTRACT

PIP: Frequency of trichomoniasis was studied in 6336 women by wet smear and Papanicolaou smear. The overall rate was 15%: 6.3% during pregnancy, 21.7% in the reproductive age group, 28.7% in women taking oral contraceptives, 22.2% in the climacteric, and 20.8% in postmenopausal women. 118 of the patients were treated with Fasigyn, a new trichomonacide. The drug was well tolerated. Oral administration sufficed for successful treatment. Complete cure was attained in 80% of those treated, and a further 12% showed significant improvement.^ieng


Subject(s)
Epidemiologic Methods , Incidence , Vaginitis , Contraceptives, Oral , Disease , Pregnancy , Research , Research Design , Vagina
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