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Int J Biol Macromol ; 74: 218-23, 2015 Mar.
Article in English | MEDLINE | ID: mdl-25485944

ABSTRACT

Pectin, a kind of plant polysaccharide, was introduced into collagen-hydroxyapatite composite system, and prepared collagen-hydroxyapatite/pectin (Col-HA/pectin) composite in situ. The structure of the composite was investigated by XRD, SEM, and FT-IR. The mechanical properties, water absorption, enzyme degradation, and cytotoxicity of the composite were investigated as well. The results show that the inorganic substance in the composite materials is hydroxyapatite in relatively low crystallinity. A new interface appeared by the interaction among hydroxyapatite and collagen-pectin, and formed smooth fine particles. The mechanical properties, water absorption, enzyme degradation, and cytotoxicity indicate a potential use in bone replacement for the new composite.


Subject(s)
Collagen/chemistry , Durapatite/chemistry , Pectins/chemistry , Animals , Biocompatible Materials/chemistry , Bone Substitutes/chemistry , Hydrophobic and Hydrophilic Interactions , Materials Testing , Rabbits , Spectroscopy, Fourier Transform Infrared , X-Ray Diffraction
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