ABSTRACT
The equalization of leg-length discrepancy during total hip arthroplasty can be achieved through the use of a simple measuring device, the Calipers Dual Pin Retractor. During total hip arthroplasty a stable reference point must be established to determine leg-length changes. The Calipers Dual Pin Retractor was developed to establish a fixed point on the pelvis, which would remain constant throughout the procedure, from which the distance to the trochanteric area could be measured prior to the dislocation of the hip. This measurement is then used to aid in the proper placement of the femoral components.
Subject(s)
Anthropometry/instrumentation , Arthroplasty, Replacement, Hip/methods , Leg Length Inequality/prevention & control , Anthropometry/methods , Humans , Intraoperative CareABSTRACT
A sustained-release drug delivery system was developed using a hydroxyapatite (HA) block loaded with adriamycin (ADR) by cenrifugation. Release of ADR was sustained for 66 days in vitro and for 4 weeks in vivo following intramuscular implantation in mice. ADR concentrations in plasma, liver, and kidney were from 0.25% to 10% of that at the implantation site. ADR-HA blocks implanted into osteogenic sarcomas in mice markedly inhibited tumor growth. This drug delivery system provides sustained release of the cancer chemotherapeutic agent and may prove useful for treating malignant tumours while minimising systemic side effects.
