ABSTRACT
Sixty-three regular male sexual partners of women with proven genital human papillomavirus (HPV) infection or its associated lesions were examined by colposcopy and biopsy (when necessary) to determine the prevalence of penile condyloma among them. Fifteen (24%) were found to have histologic evidence of condyloma. The severity of the women's lesions did not necessarily reflect that of lesions found in their sexual partners. The majority (54%) of the HPV-associated lesions were located on the penile body, followed by the penile root (25%). We found no cases of premalignant or malignant penile lesions. After controlling for the confounding factors of socioeconomic status and lesion location and comparing the data to those compiled from the English-language literature, we arrived at various theories about the very low rate of infection in our population. One possibility is the protective effect of circumcision, partly because the preputium is a major site of bacterial and viral colonization. The possibility of different strains of HPV in the Jewish Israeli population and certain socioeconomic factors that may limit the spread of sexually transmitted diseases may be the basis for future study.
Subject(s)
Condylomata Acuminata/epidemiology , Genital Diseases, Female/epidemiology , Genital Diseases, Male/epidemiology , Adult , Condylomata Acuminata/etiology , Female , Humans , Male , Middle Aged , Papillomaviridae , Sexual Partners , Uterine Cervical Dysplasia/epidemiologyABSTRACT
Viral venereal infection caused by human Papillomavirus has reached epidemic state. The proper management of this infection in men is of great benefit, because it may possibly decrease the reservoir of disease in both sexes from which genital condylomata and associated lesions may arise. We report a selection of current knowledge about the epidemiology, etiology, diagnosis, and treatment of male condyloma, occurring predominantly among male consorts of women with genital human Papillomavirus infection. In a review of 1455 affected women, compiled from the literature, 1019 (70 per cent) of their sexual partners were diagnosed as having been infected with the same viral disease. The current diagnostic and treatment modalities and their outcomes are discussed with appropriate recommendations for their use.
Subject(s)
Condylomata Acuminata , Penile Diseases , Algorithms , Biopsy , Combined Modality Therapy , Condylomata Acuminata/diagnosis , Condylomata Acuminata/epidemiology , Condylomata Acuminata/etiology , Condylomata Acuminata/therapy , Condylomata Acuminata/virology , Cryotherapy , Drug Therapy, Combination , Female , Follow-Up Studies , Genital Diseases, Female/epidemiology , Humans , Interferons/therapeutic use , Laser Therapy , Male , Papillomaviridae/isolation & purification , Penile Diseases/diagnosis , Penile Diseases/epidemiology , Penile Diseases/etiology , Penile Diseases/therapy , Penile Diseases/virologyABSTRACT
The influence of oral contraception with 0.5 mg ethynodiol diacetate (Femulen) on blood lipid and glucose tolerance test (GTT) was studied in a group of 14 nulliparous women ages 17-24 years before and 3 months after treatment. In another group of 13 women of matched age, contraception was managed by providing a combined pill (estrogen and progesterone). The continuous treatment of ethynodiol diacetate did not result in the increase in serum cholesterol and triglyceride levels and did not affect the GTT, as observed when the combined pill was administered. Femulen had no side effects, except for 2 cases of vaginal spotting. Ethynodiol diacetate does not induce the decrease in high-density lipoprotein cholesterol levels which is an anti-risk factor for the prevention of accelerated atherosclerotic disease. Oral contraception with this pill is indicated for all women, especially when there is an absolute contraindication for the use of combined pills
