1.
Biochim Biophys Acta
; 1428(2-3): 463-7, 1999 Aug 05.
Article
in English
| MEDLINE
| ID: mdl-10434066
ABSTRACT
The photo-modulation of the enzyme horseradish peroxidase modified with photochromic spiropyran dyes is reported. The degree of photo-modulation, greater than 90% reduction in enzyme activity under visible compared to UV illumination, matches the greatest degree of photo-modulation previously reported in the literature. The observation that only a small fraction of the conjugated photochromic molecules are photo-switched suggests that the dyes influence the enzyme activity via local interaction with the enzyme active site.