[Altered composition of gangliosides in the erythrocyte membrane and in the plasma of alcoholic patients]. / Veränderte Zusammensetzung für Ganglioside in den Membranen der Erythrozyten und im Plasma alkoholabhängiger Kranker.

Gangliosides were isolated from plasma and membranes of erythrocytes of alcoholics. The pattern of gangliosides were compared with the data of healthy donors. Up to 7 fractions of gangliosides could been detected after extraction, purification by column chromatography and fractionation by TLC. In alcoholics the main ganglioside fractions of plasma GM3 were increased (52.6%) and GD3 were decreased (17.5%). The GM3 and GD1b fraction of erythrocytes membranes were decreased significantly in alcoholics.