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1.
Neth Heart J ; 18(7-8): 365-9, 2010 Aug.
Article in English | MEDLINE | ID: mdl-20730004

ABSTRACT

Over the last years, measurements of quality of care have become more and more a public product, used by providers, purchasers and consumers, and patients. This information serves as an important guide for improvement, as well as a decision support tool for everybody taking part in medical treatment. This evolution can be compared with advertising and as in commercials it is important to use the right information. In this report we focus on the quality of adult cardiac surgery. Honest information is of course essential, but in this article attention is asked for the variables used to evaluate the quality of cardiac surgery. (Neth Heart J 2010;18:365-9.).

2.
Phys Med Biol ; 55(4): 963-79, 2010 Feb 21.
Article in English | MEDLINE | ID: mdl-20090186

ABSTRACT

In this study, first we propose a biplane strain imaging method using a commercial ultrasound system, yielding estimation of the strain in three orthogonal directions. Secondly, an animal model of a child's heart was introduced that is suitable to simulate congenital heart disease and was used to test the method in vivo. The proposed approach can serve as a framework to monitor the development of cardiac hypertrophy and fibrosis. A 2D strain estimation technique using radio frequency (RF) ultrasound data was applied. Biplane image acquisition was performed at a relatively low frame rate (<100 Hz) using a commercial platform with an RF interface. For testing the method in vivo, biplane image sequences of the heart were recorded during the cardiac cycle in four dogs with an aortic stenosis. Initial results reveal the feasibility of measuring large radial, circumferential and longitudinal cumulative strain (up to 70%) at a frame rate of 100 Hz. Mean radial strain curves of a manually segmented region-of-interest in the infero-lateral wall show excellent correlation between the measured strain curves acquired in two perpendicular planes. Furthermore, the results show the feasibility and reproducibility of assessing radial, circumferential and longitudinal strains simultaneously. In this preliminary study, three beagles developed an elevated pressure gradient over the aortic valve (Deltap: 100-200 mmHg) and myocardial hypertrophy. One dog did not develop any sign of hypertrophy (Deltap = 20 mmHg). Initial strain (rate) results showed that the maximum strain (rate) decreased with increasing valvular stenosis (-50%), which is in accordance with previous studies. Histological findings corroborated these results and showed an increase in fibrotic tissue for the hearts with larger pressure gradients (100, 200 mmHg), as well as lower strain and strain rate values.


Subject(s)
Aortic Valve Stenosis/diagnostic imaging , Cardiomegaly/diagnostic imaging , Echocardiography, Three-Dimensional/methods , Animals , Aortic Valve/diagnostic imaging , Child , Disease Models, Animal , Dogs , Endomyocardial Fibrosis/diagnostic imaging , Feasibility Studies , Heart Defects, Congenital/diagnostic imaging , Humans , Pilot Projects , Pressure , Radio Waves , Reproducibility of Results , Time Factors
3.
Clin Microbiol Infect ; 12(1): 84-6, 2006 Jan.
Article in English | MEDLINE | ID: mdl-16460552

ABSTRACT

This study explored the possibility of combining direct inoculation of tube coagulase and DNase tests, and the VITEK2 system, from BACTEC blood culture bottles in order to achieve rapid identification and susceptibility testing of Staphylococcus aureus. All isolates were identified correctly as S. aureus or coagulase-negative staphylococci (CNS). Antimicrobial susceptibility testing with the VITEK2 system gave 99.6% correct category agreement, with 0.1% very major errors and 0.3% minor errors among S. aureus isolates, and 97.4% correct category agreement, with 0.9% very major errors and 1.7% minor errors among CNS isolates. The results suggested that direct identification and susceptibility testing is sufficiently accurate for immediate reporting.


Subject(s)
Anti-Bacterial Agents/pharmacology , Bacterial Typing Techniques , Blood/microbiology , Culture Media , Staphylococcus aureus/classification , Staphylococcus aureus/drug effects , Bacteriological Techniques/instrumentation , Coagulase/metabolism , Deoxyribonucleases/metabolism , Humans , Microbial Sensitivity Tests , Sensitivity and Specificity , Staphylococcus/classification , Staphylococcus/drug effects , Staphylococcus/enzymology , Staphylococcus/isolation & purification , Staphylococcus aureus/enzymology , Staphylococcus aureus/isolation & purification
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