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Opt Express ; 29(23): 38606-38614, 2021 Nov 08.
Article in English | MEDLINE | ID: mdl-34808910

ABSTRACT

Alzheimer disease and related dementias affect 15-20% of elderly people, and 60-70% of these suffer from sleep disturbances. Studies suggest that lighting can improve sleep. The key challenge is how to deliver light effectively. We have designed a lighting system that adjusts spectrum and irradiance on a 24-hour timetable to provide spatially uniform, shadow-free white light with CRI>85 and up to 1000 Lux for day vision and amber light for night vision. To aid sleep, melanopic illuminance varies over 3 orders of magnitude to enable strong suppression of melatonin in the morning/early afternoon, moderate suppression in the evening, and no suppression at night.


Subject(s)
Alzheimer Disease/complications , Light , Lighting/methods , Phototherapy/methods , Sleep Wake Disorders/therapy , Vision, Ocular/physiology , Aged , Circadian Clocks/physiology , Humans , Lighting/instrumentation , Melatonin/metabolism , Phototherapy/instrumentation , Sleep Wake Disorders/etiology , Time Factors
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