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1.
Clin Otolaryngol ; 41(1): 59-65, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26095773

ABSTRACT

OBJECTIVE: To provide an independent evaluation of the efficacy and safety of the EarPopper(®) in improving hearing outcomes in children with otitis media with effusion (OME) and reducing the ventilation tube insertion rate. STUDY DESIGN: Randomised single-blinded controlled trial. SETTING: The Ear Nose and Throat Department of a district general hospital (Heatherwood and Wexham Park). PARTICIPANTS AND METHODS: Twenty-nine children aged between 4 and 11 years diagnosed with persistent OME lasting at least 3 months with an average hearing of 25 dBHL or worse in the better ear were randomised to a treatment or control group for 7 weeks using random computer-generated codes. Syndromic children, children with developmental delay, previous grommets and cleft palate were excluded. The audiologists were blinded at the final post-treatment audiogram. RESULTS: After the seven-week period, the mean improvement in air conduction across all frequencies was 10.9 dBHL in the treatment group (P < 0.001) and 3.6 dBHL in the control group (P = 0.201). At every frequency, the treatment group had larger improvements in air conduction, the largest being at 4 kHz where the mean air conduction in both ears improved by 14.8 dBHL. Compliance with the EarPopper(®) was over 90%, the only side-effect reported being discomfort in the ears immediately after use which resolved and did not affect compliance. The ventilation tube insertion rate was 53.3% in the treatment group and 78.6% in the control group. Median follow-up time for all patients is 47.7 months. CONCLUSION: Our study shows that the EarPopper(®) is a safe, effective treatment option for children with hearing loss from persistent OME, and it reduces the rate of ventilation tube insertion. More studies with larger sample sizes are required to support our findings.


Subject(s)
Hearing/physiology , Otitis Media with Effusion/therapy , Audiology/instrumentation , Child , Child, Preschool , Female , Hearing Loss/therapy , Humans , Male , Otitis Media with Effusion/complications , Safety , Treatment Outcome , Validation Studies as Topic
2.
J Laryngol Otol ; 129(6): 600-3, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25990028

ABSTRACT

BACKGROUND: Necrotising (malignant) otitis externa is a severe infection causing temporal bone osteomyelitis. Although rare, our experience (reported herein) shows local doubling of cases in 2013. Hospital Episodes Statistics data for England over 14 years also indicate increased incidence nationally. Specific learning points in management are also discussed. METHODS: A retrospective review was conducted of patients admitted in 2013 to Wexham Park Hospital, Slough, UK (catchment population, 450 000). In addition, the UK Government Hospital Episodes Statistics data were interrogated. RESULTS: There were five cases of necrotising (malignant) otitis externa in 2013, representing a local doubling on previous years. The mean age of patients was 82 years. All cultures grew Pseudomonas aeruginosa; no isolates were antibiotic resistant. All patients responded to systemic anti-pseudomonals on clinical, biochemical and radiological parameters. Hospital Episodes Statistics data showed a six-fold increase in the number of cases from 1999 (n = 67) to 2013 (n = 421). CONCLUSION: Our experience suggests increasing necrotising (malignant) otitis externa incidence, and retrospective analysis of Hospital Episodes Statistics data supports this observation. Necrotising (malignant) otitis externa poses challenges in management, as exemplified in our cases, requiring a high index of suspicion and early aggressive treatment to achieve cure.


Subject(s)
Disease Management , Otitis Externa/epidemiology , Aged , Aged, 80 and over , Female , Humans , Incidence , Male , Necrosis , Retrospective Studies , United Kingdom/epidemiology
3.
J Laryngol Otol ; 125(8): 856-8, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21481296

ABSTRACT

OBJECTIVE: Susac syndrome comprises a triad of vestibulocochlear dysfunction, retinopathy and multifocal encephalopathy, which is characterised pathophysiologically by microangiopathy of the ear, retina and brain. Diagnosis is confirmed by magnetic resonance imaging of the brain and ophthalmological examination, which reveals branch retinal artery occlusion. Hearing loss persists in 90 per cent of patients. We present a case of successful hearing rehabilitation by cochlear implantation in a young woman with this syndrome. CLINICAL PRESENTATION: A 36-year-old woman presented with neurological symptoms suggestive of encephalitis. She subsequently developed vestibulocochlear symptoms. The diagnosis was confirmed upon magnetic resonance imaging and fluorescein angiography, which showed multiple peripheral retinal arterial occlusions. Hearing loss was fluctuant but gradually progressive over nine months, to bilateral profound sensorineural hearing loss. INTERVENTION: A left cochlear implant was placed, with a good outcome. CONCLUSION: In this Susac syndrome patient, the outcome of cochlear implantation was encouraging, notwithstanding the possible involvement of retrocochlear pathways.


Subject(s)
Cochlear Implantation , Hearing Loss, Sensorineural/surgery , Susac Syndrome/surgery , Adult , Audiometry, Pure-Tone , Diagnosis, Differential , Female , Hearing Loss, Sensorineural/diagnosis , Hearing Loss, Sensorineural/rehabilitation , Humans , Magnetic Resonance Imaging , Susac Syndrome/diagnosis , Susac Syndrome/pathology , Treatment Outcome
4.
J Med Biogr ; 18(1): 24-6, 2010 Feb.
Article in English | MEDLINE | ID: mdl-20207895

ABSTRACT

This paper reflects on the life and work of Esme Hadfield, an otolaryngologist based at Wycombe General Hospital and, in particular, on her discovery of the link between adenocarcinoma of the paranasal sinuses and wood dust exposure from those in the furniture industry. The paper also explores the woodworking industry that forms the backdrop to her discovery.


Subject(s)
Adenocarcinoma/history , Dust , Occupational Exposure/history , Otolaryngology/history , Paranasal Sinus Neoplasms/history , Wood/history , Adenocarcinoma/etiology , History, 19th Century , History, 20th Century , Humans , Industry/history , Interior Design and Furnishings/history , Occupational Exposure/adverse effects , Paranasal Sinus Neoplasms/etiology , Wood/toxicity
6.
J Laryngol Otol ; 121(6): 601-5, 2007 Jun.
Article in English | MEDLINE | ID: mdl-17140460

ABSTRACT

Traumatic facial nerve neuroma is rare. There are only 10 reported cases in the literature, caused either by physical trauma or chronic inflammation. Traumatic facial neuromata differ from true facial nerve neoplasms in radiological, macroscopic and microscopic appearance, but clinical presentation is less reliable in differentiating the two. Management depends on the pre-operative grade of facial palsy, as this is a benign condition and surgical management carries a risk of further affecting facial nerve function. We present a further case of traumatic facial nerve neuroma following surgery for cholesteatoma. We also review the literature and discuss the management of this condition.


Subject(s)
Cranial Nerve Neoplasms/etiology , Facial Nerve Diseases/etiology , Facial Nerve Injuries/etiology , Mastoid/surgery , Neuroma/etiology , Adult , Audiometry , Cholesteatoma/surgery , Cranial Nerve Neoplasms/diagnostic imaging , Cranial Nerve Neoplasms/pathology , Facial Nerve Diseases/diagnostic imaging , Facial Nerve Diseases/pathology , Facial Paralysis/etiology , Female , Humans , Neuroma/diagnostic imaging , Neuroma/pathology , Otitis Media/surgery , Radiography , Severity of Illness Index
8.
Ann R Coll Surg Engl ; 87(4): 255-8, 2005 Jul.
Article in English | MEDLINE | ID: mdl-16053685

ABSTRACT

INTRODUCTION: Intra-operative peritoneal lavage (IOPL) is widely practised but its benefits are unclear. The frequency and pattern of its use amongst general surgeons is investigated. METHODS: A postal questionnaire was sent to 153 general surgical consultants and registrars enquiring about their use of IOPL. The surgeon was asked the volume and type of lavage fluid used, under various circumstances. RESULTS: 118 (77%) questionnaires were returned. 115 (97%) surgeons used IOPL. The majority of surgeons (61%) lavaged until the fluid was clear, 20% used more than 1 l and 17% used between 500-1000 ml. In the case of the dirty abdomen (i.e. gross pus or faecal peritonitis), 47% used saline as the lavage fluid, 38% aqueous betadine, 9% water and 3% antibiotic lavage. Similar results were found in the case of a contaminated abdomen (i.e. a breached hollow viscus). 34% of surgeons used IOPL during clean cases. 36% used water lavage during intra-abdominal cancer surgery; 21% lavaged with saline and 17% with betadine. More registrars (47%) than consultants (29%) lavaged with water during cancer surgery. Consultants, however, used more aqueous betadine. CONCLUSIONS: The frequency of use and choice of lavage fluid varies widely. The successful management of the septic abdomen rests on at least 3 tenants - systemic antibiotics, control of the source of infection and aspiration of gross contaminants. There is little good evidence in the literature to support IOPL in the management of the septic abdomen. The use of IOPL during cancer surgery is supported by in vitro evidence. The current use of IOPL, as shown by this study, appears not to be evidence based.


Subject(s)
General Surgery/statistics & numerical data , Intraoperative Care/methods , Peritoneal Lavage/statistics & numerical data , Anti-Infective Agents, Local , Health Care Surveys , Humans , Peritoneal Lavage/methods , Povidone-Iodine , Professional Practice/standards , Sodium Chloride , Water
9.
J Laryngol Otol ; 119(4): 322-4, 2005 Apr.
Article in English | MEDLINE | ID: mdl-15949092

ABSTRACT

Arteriovenous fistula of the superficial temporal artery is a rare condition most commonly caused by trauma. Traditional surgical treatment has been superseded by endovascular embolization. We present the case of a 40 year-old man with a traumatic arteriovenous fistula of the superficial temporal artery who was treated by endovascular embolization. The advantages of this approach are discussed, along with a brief history of the condition.


Subject(s)
Arteriovenous Fistula/therapy , Embolization, Therapeutic/methods , Scalp/injuries , Temporal Arteries/injuries , Adult , Arteriovenous Fistula/diagnostic imaging , Arteriovenous Fistula/etiology , Humans , Male , Radiography , Scalp/blood supply , Temporal Arteries/diagnostic imaging
10.
J Laryngol Otol ; 117(11): 885-8, 2003 Nov.
Article in English | MEDLINE | ID: mdl-14670151

ABSTRACT

Mucous membrane pemphigoid (MMP) is a sub-epithelial blistering disease that primarily involves mucosal surfaces but may also involve the skin. Clinically, it appears as vesiculobullous lesions of the oral cavity and eyes, but other tissues such as the nasopharyngeal and laryngeal mucosa can also be affected. Ultimately, scarring and airway stenosis may occur. The condition should be managed by a multidisciplinary team led by a dermatologist. Immunosuppressive therapy forms the mainstay of treatment, with surgery having both a diagnostic role and a use in the treatment of complications such as airway obstruction. There must be a low threshold of suspicion for laryngeal involvement in this group of patients, so that prompt action can be taken. Once laryngeal stenosis has occurred repeated endoscopic laser excision of scar tissue can be used to maintain an adequate airway. Adjuvant use of mitomycin-C can be used beneficially in the treatment of laryngeal complications of MMP.


Subject(s)
Laryngeal Diseases/etiology , Nose Diseases/etiology , Pemphigoid, Benign Mucous Membrane/complications , Adjuvants, Immunologic/therapeutic use , Adult , Airway Obstruction/etiology , Blister/etiology , Female , Hand Dermatoses/etiology , Humans , Immunosuppressive Agents/therapeutic use , Laryngoscopy , Laryngostenosis/etiology , Larynx/surgery , Laser Therapy/methods , Mitomycin/therapeutic use , Pemphigoid, Benign Mucous Membrane/drug therapy , Pemphigoid, Benign Mucous Membrane/surgery
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