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1.
Cardiovasc Intervent Radiol ; 37(4): 914-9, 2014 Aug.
Article in English | MEDLINE | ID: mdl-24091756

ABSTRACT

PURPOSE: Endovascular repair of popliteal artery aneurysms (PAA) has become increasingly popular; however, long-term patency and limb salvage rates are not fully established. METHODS: A retrospective review of all endovascular PAA repairs at our institution (from 2005 to 2012) identified 34 PAAs in 26 patients, of which 32 % presented with acute symptoms. PAA were repaired with either Hemobahn(®) or Viabahn(®) endografts, using an entirely percutaneous approach. All patients were given Clopidogrel and/or aspirin postoperatively. Mean follow-up duration was 40 (range 4-86) months. Kaplan-Meier analysis was used to determine primary patency, secondary patency, and limb salvage rates. Complications and reintervention rates also were examined. RESULTS: At 1, 3, and 5 years follow-up, the primary graft patency was 88, 82, and 82 %, respectively, and secondary patency was 90, 86, and 86 %. Amputation-free survival at 1, 3, and 5 years was 97, 94, and 94 %, respectively. Technical success was achieved in 100 %. There were five graft occlusions: one was asymptomatic, one was treated with thrombolysis successfully, and one was thrombolysed but reoccluded resulting in nondisabling claudication. Two were not suitable for thrombolysis and required amputation. The overall reintervention rate was 12 %. CONCLUSIONS: The primary and secondary patency rates of endovascular repair of PAA are equivalent to the reported outcome of open repair. Reintervention and limb salvage rate appears better than open repair. With improved long-term outcomes, endovascular repair can be considered a credible treatment strategy for routine uncomplicated PAA.


Subject(s)
Aneurysm/surgery , Endovascular Procedures , Popliteal Artery , Aged , Aneurysm/diagnosis , Angiography , Anticoagulants/administration & dosage , Female , Humans , Limb Salvage , Male , Middle Aged , Postoperative Complications , Retrospective Studies , Tomography, X-Ray Computed , Treatment Outcome , Ultrasonography, Doppler, Duplex , Vascular Patency
3.
Eur J Gastroenterol Hepatol ; 15(8): 915-9, 2003 Aug.
Article in English | MEDLINE | ID: mdl-12867803

ABSTRACT

BACKGROUND: Most patients with advanced stage malignant obstructive jaundice will be suitable for palliation only. Metallic stents are safe, effective and minimally invasive. DESIGN: A review of case notes of patients who had Wallstents inserted percutaneously from January 1996 to December 2000. RESULTS: Eighty-nine patients with a median age of 72 years underwent percutaneous insertion of biliary metal stents. The diagnoses were cholangiocarcinoma (41.5%), pancreatic carcinoma (40.5%), nodal metastases at the porta hepatis (14.6%) and gall bladder cancer (3.4%). Ninety-six per cent of patients improved their hyperbilirubinaemia to normal levels by 1 month. The median post-procedure hospital stay was 16 days. Early overall complications (within 30 days of stenting) occurred in 30% of patients (70% of these were disease related). The 30 day mortality rate was 20% (n = 18). Fifty (70%) patients were readmitted to hospital, most commonly because of carcinomatosis (16) or stent obstruction (12). The symptom-free period ranged from 2 weeks to 13 months. Median survival for all patients was 3.5 months. Survival correlated inversely with serum bilirubin at presentation (r = -0.34, P = 0.001), but not with other liver function tests. DISCUSSION: Metal wall stenting for malignant obstructive jaundice provides good palliation with low, procedure-related morbidity and mortality, but poor overall survival from disease-related morbidity. Survival significantly correlates with pre-stenting serum bilirubin levels. There is a need to identify the subgroup of patients in whom stenting has no beneficial effect.


Subject(s)
Cholestasis/therapy , Digestive System Neoplasms/therapy , Stents , Aged , Aged, 80 and over , Bile Duct Neoplasms/therapy , Bile Ducts, Intrahepatic , Cholangiocarcinoma/therapy , Cholangiopancreatography, Endoscopic Retrograde , Cholestasis/etiology , Digestive System Neoplasms/complications , Female , Gallbladder Neoplasms/complications , Gallbladder Neoplasms/therapy , Humans , Length of Stay , Liver Neoplasms/secondary , Male , Middle Aged , Pancreatic Neoplasms/complications , Pancreatic Neoplasms/therapy , Patient Readmission , Postoperative Complications/etiology , Treatment Outcome
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