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1.
Sci Rep ; 11(1): 13727, 2021 07 02.
Article in English | MEDLINE | ID: mdl-34215770

ABSTRACT

Coastal communities and infrastructure need protection from flooding and wave overtopping events. Assessment of hazard prediction methods, used in sea defence design, defence performance inspections and forecasting services, requires observations at the land-sea interface but these are rarely collected. Here we show how a database of hindcast overtopping events, and the conditions that cause them, can be built using qualitative overtopping information obtained from social media. We develop a database for a case study site at Crosby in the Northwest of England, use it to test the standard methods applied in operational flood forecasting services and new defence design, and suggest improvements to these methods. This novel approach will become increasingly important to deliver long-term, cost-effective coastal management solutions as sea-levels rise and coastal populations grow. At sites with limited, or no, monitoring or forecasting services, this approach, especially if combined with citizen science initiatives, could underpin the development of simplified early warning systems.

2.
Clin Exp Dermatol ; 36(4): 378-80, 2011 Jun.
Article in English | MEDLINE | ID: mdl-21564176

ABSTRACT

Autoimmune progesterone dermatitis (AIPD) is a rare, poorly characterized dermatosis, with about 60 previously reported cases. It typically undergoes cyclical flares relating to the menstrual cycle, especially the luteal phase, when levels of progesterone are at their highest. We report the case of a 34-year-old woman with an 8-year history of a profoundly pruritic eruption, associated with her menstrual cycle, in whom the diagnosis had proved elusive. Buserelin nasal spray resulted in complete clearance. AIPD is a diagnosis to consider in intractable eruptions in women, particularly if there is cyclical variation.


Subject(s)
Autoimmune Diseases/immunology , Menstrual Cycle/immunology , Progesterone/immunology , Adult , Autoimmune Diseases/drug therapy , Autoimmune Diseases/pathology , Buserelin/therapeutic use , Dermatitis , Female , Gonadotropin-Releasing Hormone/therapeutic use , Humans , Progesterone/adverse effects , Time Factors , Treatment Outcome
3.
Clin Exp Dermatol ; 36(3): 281-3, 2011 Apr.
Article in English | MEDLINE | ID: mdl-20738320

ABSTRACT

Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular scaly erythematous plaques in a photosensitive distribution, and the presence of anti-Ro (SSA) and/or anti-La (SSB) antibodies. Most cases of SCLE are idiopathic, but occasional cases may be drug-induced or associated with a hereditary deficiency of complement components. We report two cases of drug-induced SCLE precipitated by the proton pump inhibitor, omeprazole. Drug-induced disease should be considered in all atypical or extensive cases of SCLE, especially in elderly patients.


Subject(s)
Anti-Ulcer Agents/adverse effects , Drug Eruptions/etiology , Lupus Erythematosus, Cutaneous/chemically induced , Omeprazole/adverse effects , Aged , Aged, 80 and over , Drug Eruptions/pathology , Female , Humans , Lupus Erythematosus, Cutaneous/pathology , Proton Pump Inhibitors/adverse effects
4.
Health Care Financ Rev ; 22(4): 111-40, 2001.
Article in English | MEDLINE | ID: mdl-12378762

ABSTRACT

Health care spending estimates constitute an important public policy tool, providing a broad look at historical trends in unique State health care systems. The State health expenditure estimates presented here detail spending for the 50 States and the District of Columbia for calendar years 1980-1998. They include expenditure estimates for specific service types as well as for two major sources of funding--Medicare and Medicaid. In this article, the authors address health care's role in State economies, trends in major service sectors and payers, and factors influencing these trends.


Subject(s)
Financing, Government/trends , Health Care Surveys , Health Expenditures/trends , State Health Plans/economics , Financing, Government/statistics & numerical data , Health Expenditures/statistics & numerical data , Humans , Medicaid/statistics & numerical data , Medicaid/trends , Medicare/statistics & numerical data , Medicare/trends , State Health Plans/statistics & numerical data , State Health Plans/trends , United States
6.
Health Care Financ Rev ; 21(2): 165-210, 1999.
Article in English | MEDLINE | ID: mdl-11481774

ABSTRACT

In 1998, national health care expenditures reached $1.1 trillion, an increase of 5.6 percent from the previous year. This marked the fifth consecutive year of spending growth under 6 percent. Underlying the stability of the overall growth, major changes began taking place within the Nation's health care system. Public payers felt the initial effects of the Balanced Budget Act of 1997 (BBA), and private payers experienced increased health care costs and increased premium growth.


Subject(s)
Health Expenditures/statistics & numerical data , Health Expenditures/trends , Budgets , Data Collection , Drug Prescriptions/economics , Drug Prescriptions/statistics & numerical data , Economics, Hospital/trends , Fraud/prevention & control , Humans , Insurance, Health/statistics & numerical data , Managed Care Programs/economics , Medicaid/statistics & numerical data , Medicare/statistics & numerical data , Nursing Homes/economics , United States , United States Food and Drug Administration
8.
9.
J Sci Instrum ; 43(8): 519-20, 1966 Aug.
Article in English | MEDLINE | ID: mdl-5945258
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