ABSTRACT
By means of polyacrylamide gel and cellulose acetate enzymo-electrophoresis, the authors have studied tissue-specific isozymes of adenosine deaminase in the pig; these have been correlated to the erythrocytic ABO-like polymorphism. The enzyme product of the ADA0 gene was detected in nucleated cells; the absence of the ADA0 gene product in erythrocytes was tentatively accounted for by an increased in vivo lability.
Subject(s)
Adenosine Deaminase/metabolism , Nucleoside Deaminases/metabolism , Polymorphism, Genetic , Swine/metabolism , Animals , GenesABSTRACT
An electrophoretic survey of 13 enzymes corresponding to 19 loci has been carried out in Belgian Landrace and Pietrain pig breeds. Four of these enzymes have been shown to exhibit electrophoretically detectable polymorphism. The average heterozygosity per locus was found to be 0.066 in the Belgian Landrace and 0.028 in the Pietrain pigs.
