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Food Chem Toxicol ; 39(12): 1145-51, 2001 Dec.
Article in English | MEDLINE | ID: mdl-11696389

ABSTRACT

Blood levels of ochratoxin A were determined in 406 Scandinavian blood donors (206 from Oslo, Norway, and 200 from Visby on the island of Gotland, Sweden), using an HPLC method. In connection with the blood collection, the subjects were asked to fill in a food questionnaire to obtain individual dietary information relevant to ochratoxin A exposure. The mean plasma level of ochratoxin A was 0.18 ng/ml in Oslo and slightly higher, 0.21 ng/ml (P=0.046) in Visby. There was no correlation between plasma levels of ochratoxin A and the estimated total dietary intake of ochratoxin A based on consumption data and levels in food (retrieved from the literature), neither was the plasma level of ochratoxin A correlated with the total amount of food consumed. However, consumption of several foods, including cereal products, wine, beer and pork, were to some minor degree related to high plasma levels of ochratoxin A. The strongest correlations (correlation coefficient r>0.4; P<0.001) were observed for women in relation to the consumption of beer or medium brown bread. Correlation analysis of combinations of two or more food categories did not result in any statistically significant correlation.


Subject(s)
Carcinogens/analysis , Food Contamination/analysis , Ochratoxins/blood , Adult , Animals , Beer/analysis , Blood Donors , Chromatography, High Pressure Liquid , Edible Grain/chemistry , Female , Food Analysis , Humans , Male , Meat/analysis , Norway/epidemiology , Statistics as Topic , Surveys and Questionnaires , Sweden/epidemiology , Swine , Wine/analysis
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