ABSTRACT
OBJECTIVES: Motor evoked potentials (MEPs) were recorded in 7 cases of Creutzfeldt-Jakob disease (CJD) to asses the involvement of pyramidal motor pathways in these cases. The diagnosis of CJD was confirmed by autopsy in 5 cases and based on clinical data in two cases. METHODS: Transcranial (MEP-cortex), root magnetic (MEP-root) and electrical stimulation of peripheral nerves (F-wave, direct M-response) were performed. The cortical excitability threshold, F-wave frequency, MEP amplitudes, peripheral motor conduction velocity, standardized distal latencies and central, root, and F-wave conduction times were evaluated. RESULTS: The results of MEP testing were markedly abnormal. Cortical excitability thresholds were elevated, MEP amplitudes were reduced while the conduction function was rather preserved. The features of functional disturbances and/or loss of upper and lower motor neurons were revealed. They correlated with the advancement of key clinical CJD symptoms (progressive dementia, extrapyramidal and cerebellar signs, myoclonic jerks, mutism and typical periodic EEG changes), while motor lesion signs might only be slight or absent. CONCLUSIONS: Conduction slowing, if present, seemed to be secondary to axonal lesion.
Subject(s)
Creutzfeldt-Jakob Syndrome/physiopathology , Evoked Potentials, Motor/physiology , Adult , Aged , Electromyography , Female , Humans , Magnetics , Male , Middle Aged , Muscles/physiopathologyABSTRACT
20 patients suffering from nasal potency disturbances were carefully clinically (including self-assessment) and rhinomanometrically evaluated before and after surgical treatment. Surgery brought sufficient improvement in nasal potency and long term relief in clinical symptoms in most of the patients. Cases with only temporal release were strictly analysed. We would like to emphasize the importance to employ both surgery and accompanying conservative treatment to cure these patients with significant functional contribution.
Subject(s)
Manometry/methods , Nasal Obstruction/diagnosis , Nasal Obstruction/surgery , Adolescent , Adult , Child , Female , Humans , Male , Middle Aged , Retrospective StudiesABSTRACT
The neck cysts are the most common congenital malformation in the head and neck area. In these cases the diagnosis is established on clinical examination, the results of USG and the aspiration biopsy. The problem of malignancy was very rare, but nowadays there is much more in literature about these. The criteria of cancer diagnosis in the neck cysts metaplasia of ephitelium are mentioned. In the ENT Department in Warsaw between September 1989 until December 1994 were treated 29 patients with the neck cyst. Four of them had diagnosed as cancer in histopathological examination. Improvement of some non-invasive technique let us to use them more extensive, especially USG. The examination can be repeated many times, especially in cases when the primary neck tumor was treated using conservative methods.
Subject(s)
Carcinoma/pathology , Cysts/pathology , Head and Neck Neoplasms/pathology , Aged , Biopsy, Needle , Carcinoma/diagnostic imaging , Cysts/diagnostic imaging , Epithelium/pathology , Head and Neck Neoplasms/diagnostic imaging , Humans , Male , Metaplasia , Middle Aged , Neck/diagnostic imaging , UltrasonographyABSTRACT
Papilloma of the nose requires radical, surgical procedure, because may occur of the recurrences and metaplasia. The lateral rhinotomy is the most recommended technique as good total and radical for excision of the tumor. We present 25 cases of papilloma treated in the Otolaryngological Department in Warsaw. The new methods of the pre-, intra- and post-operative evaluation using endoscopy, especially microscope endoscopy has been used. Endoscopy is also very valid methods for post-operative monitoring follow-up.
