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Mech Ageing Dev ; 27(1): 83-6, 1984 Sep.
Article in English | MEDLINE | ID: mdl-6492889

ABSTRACT

Several theories of ageing predict that somatic mutations should increase with age. This prediction was tested for human lymphocytes using a recently developed clonal technique for enumeration of mutations, and an increase of 1.6% per year in mutations with age was detected.


Subject(s)
Aging , Lymphocytes/cytology , Mutation , Adolescent , Adult , Aged , Cells, Cultured , Child , Child, Preschool , Clone Cells , Humans , Infant , Infant, Newborn , Middle Aged
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