[Basic diagnostic program in dizziness and syncope symptoms: value of electrophysiologic studies of the heart]. / Diagnostisches Basisprogramm bei der Symptomatik Schwindel und Synkope: Stellenwert elektrophysiologischer Untersuchungen des Herzens.

Syncopes and preceding signs and symptoms, particularly also in form of appearances of giddiness, are, including specialists of various branches, among others ENT, neurology, orthopaedics and ophthalmology, always to be classified according to the fact whether or not a cardiovascular disease is to be regarded as cause. If there is the suspicion, both special non-invasive investigations and such ones which possibly are to be performed invasively are indicated. The latter come after the non-invasive investigations partly on account of the expenditure (technique of heart catheterization) and the possibilities of complication. The testing of the sinus node with the highly frequent atrial stimulation and single stimulus technique, the lead of the His-potential and the performance of a ventricular programmed stimulation are the fundamental programmes of an electrophysiologic investigation. In an analysis carried out more than 3 years could be found that in two thirds of the 45 invasively examined patients the diagnosis could be precised and enhanced, respectively, and that the main disturbances related to the signs and symptoms were a sick sinus syndrome, AV-asequences and ventricular arrhythmias.

[Diagnosis and therapy of ventricular tachycardia in heart failure]. / Diagnostik und Therapie der ventrikulären Tachykardie bei Herzinsuffizienz.

In a survey diagnostic and therapeutic problems of the ventricular arrhythmias in cardiac insufficiency are described. It is expressed that prevalence and prognosis of the arrhythmia in cardiac insufficiency are not yet sufficiently investigated both in the acute and in the chronic phase. Furthermore, ascertained investigations concerning the effect of the individual antiarrhythmic drugs have not come to hand. Certain situations and preliminary electrocardiographic findings are to be regarded as premonitory signs; in the individual case they are entitled to a prophylactic therapy with antiarrhythmic drugs. The consideration of pharmacokinetic laws is particularly significant in the disturbed metabolization and the reduction of the hepatic blood in this phase.

[Serum level determination in patients with acute myocardial infarction under diphenylhydantoin therapy]. / Serumspiegelbestimmungen bei Patienten mit akutem Myokardinfarkt unter der Therapie mit Diphenylhydantoin.

For the therapy of disturbances of the cardiac rhythm with phenytoin 3 different dosage regimes are examined, in which cases an oral application of phenytoin proves as not suitable. Only by a stepped infusion with following oral treatment a rapid saturation and therapeutically effective serum levels are achieved which are decisive for the effectiveness of the therapeutic measures.