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1.
Z Gerontol Geriatr ; 42(4): 299-304, 2009 Aug.
Article in German | MEDLINE | ID: mdl-19680709

ABSTRACT

The article provides a short overview on cognitive strengths and weaknesses of older workers. The older people who are under the age of 65 years already exhibit changes in performance and neurophysiological measures in laboratory tasks that test fluid intelligence. Apart from deficits, the physiological data of the older people show clear evidence for compensatory strategies. Cognitive performance on the current job is usually less impaired. This can be explained by practice, learning, and selection, which are, however, often linked with higher effort. The cognitive competence of older employees varies exorbitantly, which is due to the influence of various factors like education, lifestyle, and in particular the type of work. Thus, the cognitive competence of older employees can be preserved and possibly even enhanced by changes in the work situation as well as by individual training procedures such as cognitive training.


Subject(s)
Aging/physiology , Cognition/physiology , Employment/trends , Age Factors , Aged , Aged, 80 and over , Female , Germany , Humans , Male
2.
Schizophr Res ; 76(1): 25-41, 2005 Jul 01.
Article in English | MEDLINE | ID: mdl-15927796

ABSTRACT

Mismatch negativity (MMN) is an event-related potential measure of auditory change detection. It is widely reported to be smaller in patients with schizophrenia and may not improve along with otherwise successful clinical treatment. The main aim of this report is to explore ways of measuring and presenting four features of frequency-deviant MMN dipole sources (dipole moment, peak latency, brain location and orientation) and to relate these to the processes of psychopathology and illness progression. Data from early onset patients (EOS) at the start of the illness in adolescence, and others who had their first break in adolescence 15 years ago (S-15Y) were compared with two groups of age-matched healthy controls (C-EOS, C-15Y). A four-source model fitted the MMN waveform recorded from all four groups, whether MMN amplitude was more (EOS) or less (S-15Y) reduced. The locations were in the left superior temporal and anterior cingulate gyri, right superior temporal and inferior/mid frontal cortices. Dipole latencies confirmed a bottom-up sequence of processing and dipole moments were larger in the temporal lobes and on the left. Patients showed small dipole location changes that were more marked in the S-15Y than the EOS group (more rostral for the left anterior cingulate, more caudal for the right mid-frontal dipole) consistent with illness progression. The modelling of MMN dipole sources on brain atlas and anatomical images suggests that there is a degree of dissociation during illness between small progressive anatomical changes and some functional recovery indexed by scalp recordings from patients with an onset in adolescence 15 years before compared to adolescents in their first episode.


Subject(s)
Contingent Negative Variation/physiology , Evoked Potentials, Auditory/physiology , Frontal Lobe/physiopathology , Schizophrenia/diagnosis , Schizophrenic Psychology , Temporal Lobe/physiopathology , Adolescent , Adult , Attention/physiology , Brain Mapping , Chronic Disease , Disease Progression , Dominance, Cerebral/physiology , Electroencephalography , Female , Gyrus Cinguli/physiopathology , Humans , Male , Reference Values , Schizophrenia/physiopathology , Sensitivity and Specificity
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