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Bioorg Med Chem Lett
; 19(6): 1658-61, 2009 Mar 15.
Article
in English
| MEDLINE
| ID: mdl-19231183
ABSTRACT
A series of pyrimidine nitrile inhibitors of Cathepsin K with reduced glutathione reactivity has been identified and Molecular Core Matching (MoCoM) has been used to quantify the effect of an amino substituent at C5.