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1.
Prev Vet Med ; 40(3-4): 151-63, 1999 Jun 11.
Article in English | MEDLINE | ID: mdl-10423771

ABSTRACT

The prevalence and distribution of seropositivity towards the protozoan parasite Neospora caninum were studied in single blood samples from 1561 cows from 31 Danish dairy herds. Blood samples were analysed by an indirect enzyme-linked immunoassay and an indirect fluorescent-antibody test. Seroprevalence in 15 herds with previous abortions assigned to neosporosis ranged from 1% to 58%, with a mean frequency of 22%. In eight out of 16 herds without a history of N.caninum related abortions, no seroreactors were found. In the remaining eight herds, the seroprevalence ranged from 6% to 59%. The prevalence and distribution of seropositivity, gestation number prior to sampling, and breed were related to abortions and perinatal deaths using a random-effects logistic-regression model. Abortion risk was significantly increased in seropositive animals (OR = 3) and in > or = 2nd-gestation cows (OR = 3). Perinatal death was significantly influenced by gestation number and breed, but not by serostatus. Reproductive performance and culling risk of cows were not affected by serostatus. Seropositivity increased with "age" (i.e. gestation number) (P = 0.02). In open cows, seropositivity tended to decrease with distance from calving (P = 0.05). The proportion of seropositive pregnant cows increased with trimester (P = 0.02).


Subject(s)
Cattle Diseases/immunology , Coccidiosis/veterinary , Dairying , Neospora/immunology , Pregnancy Complications, Parasitic/veterinary , Pregnancy Outcome/veterinary , Abortion, Veterinary/parasitology , Animals , Antibodies, Protozoan/analysis , Antigens, Protozoan/immunology , Cattle , Cattle Diseases/epidemiology , Cattle Diseases/parasitology , Coccidiosis/epidemiology , Coccidiosis/immunology , Coccidiosis/parasitology , Denmark/epidemiology , Enzyme-Linked Immunosorbent Assay/veterinary , Female , Fluorescent Antibody Technique, Indirect/veterinary , Litter Size , Male , Pregnancy , Pregnancy Complications, Parasitic/epidemiology , Pregnancy Complications, Parasitic/immunology , Pregnancy Complications, Parasitic/parasitology , Seroepidemiologic Studies
2.
Zentralbl Veterinarmed A ; 44(9-10): 551-8, 1997 Dec.
Article in English | MEDLINE | ID: mdl-9465775

ABSTRACT

Diagnostic findings in 218 aborted bovine foetuses are reported. The materials were examined in a matched case-control study of 69 Danish dairy herds with a sudden increase in the number of abortions and a corresponding 69 control herds. Foetuses aborted during the subsequent 6-month period were examined to identify the cause of abortion if possible. A total of 186 specimens were submitted from case herds and 32 from control herds. A likely cause of abortion was diagnosed in 73 foetuses. The most common cause was bovine viral diarrhoea virus (BVDV: 13%) followed by Neospora caninum infection (10%), mycosis (5%) and Bacillus licheniformis infection (4%). Foetal and/or placental lesions were found in a further 27 cases. Only BVDV infection and neosporosis were diagnosed in more than one foetus per herd and only protozoal associated abortions occurred significantly more frequently in the case, rather than in the control, herds.


Subject(s)
Abortion, Septic/veterinary , Abortion, Veterinary/etiology , Cattle Diseases/diagnosis , Abortion, Septic/epidemiology , Abortion, Septic/etiology , Abortion, Veterinary/epidemiology , Animals , Bacterial Infections/complications , Bacterial Infections/diagnosis , Bacterial Infections/veterinary , Bovine Virus Diarrhea-Mucosal Disease/complications , Bovine Virus Diarrhea-Mucosal Disease/diagnosis , Bovine Virus Diarrhea-Mucosal Disease/epidemiology , Case-Control Studies , Cattle , Cattle Diseases/epidemiology , Cattle Diseases/etiology , Coccidiosis/complications , Coccidiosis/diagnosis , Coccidiosis/veterinary , Denmark/epidemiology , Female , Incidence , Neospora , Pregnancy
3.
J Am Vet Med Assoc ; 171(12): 1255-9, 1977 Dec 15.
Article in English | MEDLINE | ID: mdl-604324

ABSTRACT

The transfer of immunoglobulin G (IgG) and immunoglobulin M (IgM) from ewe to lamb was quantitated to determine the occurrence of failure in passive transfer. Concentrations of IgG and IgM in ewe serum did not correlate with those in the colostrum. Colostrum from all ewes contained abundant amounts of immunoglobulins when compared with serum values, with IgG being selectively concentrated over IgM. Absorption through the intestinal tract of the lamb appeared to be a nonselective process, lacking predilection for IgG and IgM. All lambs tested 24 hours after birth absorbed colostral immunoglobulins to some extent; however, 13 (14%) of 91 clinically normal lambs demonstrated some failure of passive transfer. In contrast, failure of passive transfer was found in 27 (46%) of 59 lambs dying of natural causes between 24 hours and 5 weeks of age. Evidence presented emphasizes the importance of absorption of adequate amounts of immunoglobulins to enable the newborn lamb to survive the first few weeks of life.


Subject(s)
Animals, Newborn/immunology , Colostrum/immunology , Immunization, Passive , Immunoglobulins/analysis , Sheep Diseases/mortality , Sheep/immunology , Animals , Female , Immunoglobulin G/analysis , Immunoglobulin M/analysis , Sheep Diseases/immunology
4.
J Am Vet Med Assoc ; 171(12): 1260-4, 1977 Dec 15.
Article in English | MEDLINE | ID: mdl-604325

ABSTRACT

A survey was conducted to determine the prevalence of toxoplasma antibodies among breeding ewes and among lambs slaughtered for food in western United States. Each serum was tested by the indirect hemaglutination method, using microtiter technique. Agglutination (greater than or equal to 2 +) at the 1:64 dilution was considered to be a positive reaction. Of 2,164 ewes from 18 flocks tested in California, 523 (24%) were seropositive for Toxoplasma gondii, with prevalence rates among flocks ranging from 4 to 51%. In 9 of those flocks, 1,495 ewes were stratified by whether ewes had lambed or were barren. On an overall basis, the antibody prevalence was similar (about 25%) in both groups, but there was a significant difference (P less than 0.05) in 1 flock in which 30% of the nursing ewes were seropositive, compared with 21% of the barren ewes. Of 1,056 market lambs from 19 lots tested, 85 (8%) were seropositive. The antibody prevalence in lambs tested at slaughter in California, by state of origin, were: Oregon, 11/51 (22%); Nevada, 32/159 (20%); Idaho, 12/147 (5%), and California, 30/699 (4%).


Subject(s)
Antibodies/analysis , Sheep/immunology , Toxoplasma/immunology , Abortion, Veterinary/epidemiology , Age Factors , Animals , Female , Pregnancy , Reproduction , Sheep/physiology , Sheep Diseases/epidemiology , United States
5.
Nord Vet Med ; 29(12): 513-28, 1977 Dec.
Article in English | MEDLINE | ID: mdl-600692

ABSTRACT

From a Danish dairy herd comprising 350 milking cows data were obtained on all (1010) single, liveborn calves dropped over a three year period. Deaths incurred before, during, and immediately after delivery were not included in the study. The mortality rate up to the first few hours after birth was 10% leaving 910 calves to be included in the present study. The overall respiratory disease (r.d.) attack rate among calves from birth up to the end of the sixth month was 23%; the r.d. case fatality rate was 40%; the r.d. mortality rate was 9%. The mortality rate due to ailments other than r.d. was 11%, and the overall mortality rate during the first six months of life was 20%. The economic impact of r.d. in the herd was evaluated using a disease model which, in mathemathical terms, conceptualizes the basic patterns of the disorders within the calf population. The economic implications of various changes in the prevailing herd health status with respect to r.d. are outlined and discussed (Table VII, IX, XI). Also the economic expectations under different sales policies were studied (Table VIII and X). The study clearly demonstrates the versality of health models and how these may be applied to prepare economic forecasts during periods with rapidly changing market and production conditions.


Subject(s)
Cattle Diseases/economics , Respiratory Tract Diseases/veterinary , Animals , Cattle , Cattle Diseases/mortality , Denmark , Disease Models, Animal , Respiratory Tract Diseases/economics , Respiratory Tract Diseases/mortality
6.
J Am Vet Med Assoc ; 167(7): 565-8, 1975 Oct 01.
Article in English | MEDLINE | ID: mdl-1176348

ABSTRACT

Blood samples were obtained from native mammals and birds on a sheep range (Hopland Field Station) in northern California. Serums were tested for antibodies to Toxoplasma gondii by the indirect hemagglutination test. Of 382 deer that were tested from 1964 to 1973, 77 (20%) were seropositive for T gondii. Among 36 serums representing 6 species of wild carnivores (badgers, bobcats, coyotes, foxes, raccoons, and skunks), 18 (50%) were seropositive. All of the 5 bobcats tested were seropositive, with antibody titers ranging from 1:65,536. The testing of 175 serums from small wild mammals indicated antibody prevalence of 8% among jackrabbits, 6% among brush rabbits, and 2% among squirrels. None of the native mice tested was seropositive for T gondii. Of 120 native birds tested, 6 (5%) were seropositive. Of the resident domestic species of animals tested, antibodies were found in 1 of 7 domestic cats, 1 of 5 feral cats, 1 of 2 dogs, and 54 (13%) of 405 sheep.


Subject(s)
Antibodies/analysis , Deer/immunology , Sheep/immunology , Toxoplasma/immunology , Animals , Birds/immunology , California , Carnivora/immunology , Cats/immunology , Dogs/immunology , Female , Male , Rabbits/immunology
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