Circling, hemispheric asymmetry, and left-right discrimination.

Three measures of rotational/side preference--amphetamine-induced circling, side of exit from open field start square, and side of turn when suspended by the tail--were assessed, and animals were then tested on a left-right discrimination. In a strong replication of a previous finding, rats showing amphetamine-induced rotation learned and retained the spatial discrimination markedly better than non-rotators. The other directional measures were unrelated to discrimination learning.