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1.
Int J Behav Nutr Phys Act ; 20(1): 17, 2023 02 14.
Article in English | MEDLINE | ID: mdl-36788615

ABSTRACT

BACKGROUND: A high sedentary time is associated with increased mortality risk. Previous studies indicate that replacement of sedentary time with light- and moderate-to-vigorous physical activity attenuates the risk for adverse outcomes and improves cardiovascular risk factors. Patients with cardiovascular disease are more sedentary compared to the general population, while daily time spent sedentary remains high following contemporary cardiac rehabilitation programmes. This clinical trial investigated the effectiveness of a sedentary behaviour intervention as a personalised secondary prevention strategy (SIT LESS) on changes in sedentary time among patients with coronary artery disease participating in cardiac rehabilitation. METHODS: Patients were randomised to usual care (n = 104) or SIT LESS (n = 108). Both groups received a comprehensive 12-week centre-based cardiac rehabilitation programme with face-to-face consultations and supervised exercise sessions, whereas SIT LESS participants additionally received a 12-week, nurse-delivered, hybrid behaviour change intervention in combination with a pocket-worn activity tracker connected to a smartphone application to continuously monitor sedentary time. Primary outcome was the change in device-based sedentary time between pre- to post-rehabilitation. Changes in sedentary time characteristics (prevalence of prolonged sedentary bouts and proportion of patients with sedentary time ≥ 9.5 h/day); time spent in light-intensity and moderate-to-vigorous physical activity; step count; quality of life; competencies for self-management; and cardiovascular risk score were assessed as secondary outcomes. RESULTS: Patients (77% male) were 63 ± 10 years and primarily diagnosed with myocardial infarction (78%). Sedentary time decreased in SIT LESS (- 1.6 [- 2.1 to - 1.1] hours/day) and controls (- 1.2 [ ─1.7 to - 0.8]), but between group differences did not reach statistical significance (─0.4 [─1.0 to 0.3]) hours/day). The post-rehabilitation proportion of patients with a sedentary time above the upper limit of normal (≥ 9.5 h/day) was significantly lower in SIT LESS versus controls (48% versus 72%, baseline-adjusted odds-ratio 0.4 (0.2-0.8)). No differences were observed in the other predefined secondary outcomes. CONCLUSIONS: Among patients with coronary artery disease participating in cardiac rehabilitation, SIT LESS did not induce significantly greater reductions in sedentary time compared to controls, but delivery was feasible and a reduced odds of a sedentary time ≥ 9.5 h/day was observed. TRIAL REGISTRATION: Netherlands Trial Register: NL9263. Outcomes of the SIT LESS trial: changes in device-based sedentary time from pre-to post-cardiac rehabilitation (control group) and cardiac rehabilitation + SIT LESS (intervention group). SIT LESS reduced the odds of patients having a sedentary time >9.5 hours/day (upper limit of normal), although the absolute decrease in sedentary time did not significantly differ from controls. SIT LESS appears to be feasible, acceptable and potentially beneficial, but a larger cluster randomised trial is warranted to provide a more accurate estimate of its effects on sedentary time and clinical outcomes. CR: cardiac rehabilitation.


Subject(s)
Coronary Artery Disease , Myocardial Infarction , Humans , Male , Female , Coronary Artery Disease/rehabilitation , Sedentary Behavior , Secondary Prevention , Quality of Life , Myocardial Infarction/prevention & control
2.
BMJ Open Sport Exerc Med ; 8(2): e001364, 2022.
Article in English | MEDLINE | ID: mdl-35692440

ABSTRACT

Patients with coronary artery disease (CAD) are more sedentary compared with the general population, but contemporary cardiac rehabilitation (CR) programmes do not specifically target sedentary behaviour (SB). We developed a 12-week, hybrid (centre-based+home-based) Sedentary behaviour IntervenTion as a personaLisEd Secondary prevention Strategy (SIT LESS). The SIT LESS programme is tailored to the needs of patients with CAD, using evidence-based behavioural change methods and an activity tracker connected to an online dashboard to enable self-monitoring and remote coaching. Following the intervention mapping principles, we first identified determinants of SB from literature to adapt theory-based methods and practical applications to target SB and then evaluated the intervention in advisory board meetings with patients and nurse specialists. This resulted in four core components of SIT LESS: (1) patient education, (2) goal setting, (3) motivational interviewing with coping planning, and (4) (tele)monitoring using a pocket-worn activity tracker connected to a smartphone application and providing vibrotactile feedback after prolonged sedentary bouts. We hypothesise that adding SIT LESS to contemporary CR will reduce SB in patients with CAD to a greater extent compared with usual care. Therefore, 212 patients with CAD will be recruited from two Dutch hospitals and randomised to CR (control) or CR+SIT LESS (intervention). Patients will be assessed prior to, immediately after and 3 months after CR. The primary comparison relates to the pre-CR versus post-CR difference in SB (objectively assessed in min/day) between the control and intervention groups. Secondary outcomes include between-group differences in SB characteristics (eg, number of sedentary bouts); change in SB 3 months after CR; changes in light-intensity and moderate-to-vigorous-intensity physical activity; quality of life; and patients' competencies for self-management. Outcomes of the SIT LESS randomised clinical trial will provide novel insight into the effectiveness of a structured, hybrid and personalised behaviour change intervention to attenuate SB in patients with CAD participating in CR. Trial registration number NL9263.

3.
Neth Heart J ; 22(12): 552-6, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25294642

ABSTRACT

Patients with chest pain have a large impact on available resources in coronary emergency rooms (CER). Clinical judgement, ECG, risk scores and biomarkers guide in risk stratification. We investigated if high-sensitivity troponin T (HsT) and the HEART Score could contribute to risk stratification at the CER. All patients with chest pain, without elevated conventional troponin levels at presentation, were included. HsT levels were determined at admission (T1), at 4-6 h (T2) and 8-10 h after symptom onset (T3). The HEART Score was calculated as risk score for the occurrence of a major adverse cardiac event (MACE). Thirty days after discharge, occurrence of MACE was registered. Eighty-nine patients were included (overall mean age 61 years (range 20-90)). At presentation, 68 patients (76 %) had a HsT below cut-off value of 14 ng/l (mean HEART Score 3.7, range 1-9). Thirty-one of these 68 patients had a HEART Score between 1-3, no MACE occurred in this group. For 3 patients (4 %) HsT levels increased above 14 ng/l. These 3 patients had a HEART Score between 4-6. The majority of patients with chest pain can be safely discharged within 4-6 h after onset of symptoms using HsT and the HEART Score. In contrast, patients with initially normal HsT but a high HEART Score need longer follow-up and repeat HsT determination.

4.
Neth Heart J ; 21(7-8): 354-63, 2013 Jul.
Article in English | MEDLINE | ID: mdl-23700039

ABSTRACT

BACKGROUND: Rhythm control for atrial fibrillation (AF) is cumbersome because of its progressive nature caused by structural remodelling. Upstream therapy refers to therapeutic interventions aiming to modify the atrial substrate, leading to prevention of AF. OBJECTIVE: The Routine versus Aggressive upstream rhythm Control for prevention of Early AF in heart failure (RACE 3) study hypothesises that aggressive upstream rhythm control increases persistence of sinus rhythm compared with conventional rhythm control in patients with early AF and mild-to-moderate early systolic or diastolic heart failure undergoing electrical cardioversion. DESIGN: RACE 3 is a prospective, randomised, open, multinational, multicenter trial. Upstream rhythm control consists of angiotensin converting enzyme inhibitors and/or angiotensin receptor blockers, mineralocorticoid receptor antagonists, statins, cardiac rehabilitation therapy, and intensive counselling on dietary restrictions, exercise maintenance, and drug adherence. Conventional rhythm control consists of routine rhythm control therapy without cardiac rehabilitation therapy and intensive counselling. In both arms, every effort is made to keep patients in the rhythm control strategy, and ion channel antiarrhythmic drugs or pulmonary vein ablation may be instituted if AF relapses. Total inclusion will be 250 patients. If upstream therapy proves to be effective in improving maintenance of sinus rhythm, it could become a new approach to rhythm control supporting conventional pharmacological and non-pharmacological rhythm control.

5.
Int J Cardiol ; 74(2-3): 199-205, 2000 Jul 31.
Article in English | MEDLINE | ID: mdl-10962122

ABSTRACT

UNLABELLED: Little is known about the value of electrocardiography in primary care. AIMS: To assess whether electrocardiography (ECG) is a useful instrument, in addition to history taking and physical examination, in that it changes the general practitioner's management of patients with suspected cardiovascular symptoms or disease. METHODS AND RESULTS: We performed a prospective study in a group practice of eight general practitioners in The Netherlands. During 2 years all ECGs that were recorded in these practices were studied. Two questionnaires were filled out by the general practitioners, one before and one after the ECG recording, to determine indication for electrocardiography, the general practitioner's anticipated management before and after ECG results, and the subjective usefulness according to the applying doctor. All ECGs were reviewed by an experienced general practitioner working in the group practice and later on by a cardiologist. In addition, all clinical information, including the 6 months follow-up period, was scrutinised by both the cardiologist and general practitioner to establish the patients' prognosis. A total of 301 ECGs was included in the analysis. Main indications for electrocardiography were chest pain (57%), and collapse or palpitation (30%). In 92 (30.6%; 95% CI 25.4-35.8) patients a change in management by the general practitioner occurred following the ECG results. Most prevalent changes were non-referral to a cardiologist, while referral was anticipated before the ECG results (34%), referral while the patient would not have been referred without ECG results (20%), and change in cardiovascular therapy (40%). In one of these cases only, this change could be considered unfavourable, since a subendocardial infarction, not detectable on the ECG, was missed. In patients with chest pain, a normal ECG (likelihood ratio (LR) 0.06) and an abnormal ECG (LR 13.3) were very useful to distinguish between patients likely or unlikely to experience cardiac events in the near future. The mean subjective usefulness, on a scale of 0-100, of the ECG evaluation according to the applying general practitioner was 77. 5 (S.D. 14.4). There was good agreement in ECG interpretation between the experienced general practitioner, the cardiologist and a second general practitioner. CONCLUSION: Electrocardiography in addition to history taking and physical examination, may be an important tool in primary care. It can reduce considerably the number of unnecessary referrals.


Subject(s)
Cardiovascular Diseases/diagnosis , Electrocardiography , Primary Health Care/methods , Adolescent , Adult , Aged , Aged, 80 and over , Chest Pain , Diagnosis, Differential , Female , Humans , Male , Medical History Taking , Middle Aged , Netherlands , Physical Examination , Prospective Studies , Sensitivity and Specificity
6.
Ann Emerg Med ; 23(5): 1003-8, 1994 May.
Article in English | MEDLINE | ID: mdl-8185090

ABSTRACT

STUDY OBJECTIVE: To investigate the ability of laypeople to apply basic CPR techniques after recent training. DESIGN: Cross-sectional assessment of practical CPR skills. TYPE OF PARTICIPANTS: 151 laypeople who were trained twice in the preceding 20 to 24 months. MEASUREMENTS AND MAIN RESULTS: Practical skills were tested using six primary recorded variables that describe the quality of CPR techniques in a training situation. A total score on the skills of each participant was computed on the basis of a predefined scoring system. Thirty-three percent of the participants were able to perform adequate CPR. The compression:relaxation ratio, the breathing volume, and the breathing interval were points of concern. CONCLUSION: Practical skills in basic CPR after a 12-month training interval, though better in this study than in many previous studies, are insufficient in the majority of laypeople. The results of this study could be used to design a better tailored (re)instruction program, with an emphasis on regular, frequent refresher courses.


Subject(s)
Cardiopulmonary Resuscitation/education , Clinical Competence/standards , Health Education/standards , Adolescent , Adult , Aged , Cardiopulmonary Resuscitation/methods , Cross-Sectional Studies , Educational Measurement , Female , Humans , Male , Middle Aged , Program Evaluation
7.
Heart Lung ; 22(6): 509-15, 1993.
Article in English | MEDLINE | ID: mdl-8288454

ABSTRACT

OBJECTIVE: To investigate the ability of qualified general nurses to perform cardiopulmonary resuscitation and to compare these skills with those of a group of ambulance nurses. DESIGN: Cross-sectional assessment of practical cardiopulmonary resuscitation skills. SUBJECTS: 141 Dutch general nurses. OUTCOME MEASURES: The practical skills were tested with six primary variables that describe the quality of cardiopulmonary resuscitation techniques in a training situation. A total score on the skills was computed based on a predefined scoring system. RESULTS: The percentage of general nurses who were able to achieve a pass score (i.e., the total score did not exceed 15 penalty points) was 6.4 percent. The average score was 37.8 penalty points. Eighty-eight percent of the ambulance nurses achieved a pass score. The average number of penalty points was 10.5. CONCLUSIONS: The practical skills in cardiopulmonary resuscitation are insufficient in the majority of this sample of general nurses in The Netherlands. The findings of this study should be used as a base to design an optimal form and content of an educational re-instruction program. We expect that a considerable improvement could be achieved by more frequent cardiopulmonary resuscitation re-instruction.


Subject(s)
Ambulances , Cardiopulmonary Resuscitation/nursing , Emergency Nursing , Nursing Staff, Hospital , Adult , Cardiopulmonary Resuscitation/education , Clinical Competence , Educational Measurement , Female , Humans , Male , Middle Aged , Netherlands
9.
Lancet ; 339(8800): 1019-20, 1992 Apr 25.
Article in English | MEDLINE | ID: mdl-1349054

ABSTRACT

During instruction in basic cardiopulmonary resuscitation (CPR) skills, cardiac massage and mouth-to-mouth ventilation are applied without interruption for no longer than a few minutes. The aim of this study was to see if the quality of technique during the first 2 min of CPR reflects the resuscitators ability to perform CPR over a 15 min period. Assessments were done with a resuscitation mannequin from which recordings of several variables were made at 2, 5, 10, and 15 min after the start of CPR. 60 lay volunteers who had received CPR training were studied, and six variables that describe the quality of CPR technique were recorded and scored with a predefined scoring system. No deterioration in CPR skills was seen during 15 min. We conclude that the initial 2 min assessment reflects the resuscitators ability to perform CPR over a longer period.


Subject(s)
Cardiopulmonary Resuscitation/standards , Adult , Female , Humans , Male , Middle Aged , Netherlands , Quality of Health Care , Time Factors
10.
Resuscitation ; 23(1): 21-31, 1992 Feb.
Article in English | MEDLINE | ID: mdl-1315067

ABSTRACT

A valid and reproducible system for determining basic cardiac life support (BCLS) skills can help to evaluate the effect of instruction courses and to estimate the results of educational activities. The aim of this study was to develop and test such a system in accordance with the Standards and Guidelines of the American Heart Association (AHA). Five criteria were defined in advance towards such a system (1) Inadequate techniques must be reflected by a fail score. (2) Skilled persons should achieve a pass score. (3) The effect of training must be reflected by an improvement of the score. (4) Inter- and intra-observer variability must be negligible. (5) The system should be simple to apply. The system was developed, and in order to test the system, the BCLS skills of 40 ambulance nurses were tested once and those of 148 lay people twice. All cardiopulmonary resuscitation (CPR) attempts were performed on a mannequin. The relevant parameters of the attempt were continuously recorded and printed. Penalty points were assigned in a predefined way for aberrations of the techniques advised in the Standards and Guidelines. The system satisfied the five criteria mentioned above. It therefore offers a reliable and reproducible evaluation of BCLS skills.


Subject(s)
Allied Health Personnel/education , Cardiopulmonary Resuscitation/education , Educational Measurement , Humans , Manikins
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