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1.
Anesthesiology ; 136(6): 901-915, 2022 06 01.
Article in English | MEDLINE | ID: mdl-35188958

ABSTRACT

BACKGROUND: Residual neuromuscular blockade can be avoided with quantitative neuromuscular monitoring. The authors embarked on a professional practice initiative to attain documented train-of-four ratios greater than or equal to 0.90 in all patients for improved patient outcomes through reducing residual paralysis. METHODS: The authors utilized equipment trials, educational videos, quantitative monitors in all anesthetizing locations, and electronic clinical decision support with real-time alerts, and initiated an ongoing professional practice metric. This was a retrospective assessment (2016 to 2020) of train-of-four ratios greater than or equal to 0.9 that were documented before extubation. Anesthesia records were manually reviewed for neuromuscular blockade management details. Medical charts of surgical patients who received a neuromuscular blocking drug were electronically searched for patient characteristics and outcomes. RESULTS: From pre- to postimplementation, more patients were assigned American Society of Anesthesiologists Physical Status III to V, fewer were inpatients, the rocuronium average dose was higher, and more patients had a prereversal train-of-four count less than 4. Manually reviewed anesthesia records (n = 2,807) had 2 of 172 (1%) cases with documentation of train-of-four ratios greater than or equal to 0.90 in November 2016, which was fewer than the cases in December 2020 (250 of 269 [93%]). Postimplementation (February 1, 2020, to December 31, 2020), sugammadex (650 of 935 [70%]), neostigmine (195 of 935 [21%]), and no reversal (90 of 935 [10%]) were used to attain train-of-four ratios greater than or equal to 0.90 in 856 of 935 (92%) of patients. In the electronically searched medical charts (n = 20,181), postimplementation inpatients had shorter postanesthesia care unit lengths of stay (7% difference; median [in min] [25th, 75th interquartile range], 73 [55, 102] to 68 [49, 95]; P < 0.001), pulmonary complications were less (43% difference; 94 of 4,138 [2.3%] to 23 of 1,817 [1.3%]; P = 0.010; -1.0% difference [95% CI, -1.7 to -0.3%]), and hospital length of stay was shorter (median [in days] [25th, 75th], 3 [2, 5] to 2 [1, 4]; P < 0.001). CONCLUSIONS: In this professional practice initiative, documentation of train-of-four ratios greater than or equal to 0.90 occurred for 93% of patients in a busy clinical practice. Return-of-strength documentation is an intermediate outcome, and only one of many factors contributing to patient outcomes.


Subject(s)
Neuromuscular Blockade , Neuromuscular Nondepolarizing Agents , Humans , Neostigmine , Neuromuscular Blockade/adverse effects , Neuromuscular Monitoring , Neuromuscular Nondepolarizing Agents/adverse effects , Professional Practice , Retrospective Studies
2.
J Am Coll Radiol ; 18(10): 1423-1429, 2021 10.
Article in English | MEDLINE | ID: mdl-34043974

ABSTRACT

PURPOSE: Hepatic steatosis is a common incidental finding on abdominal imaging that is not always reported or recognized as having clinical significance. Because of its association with liver disease, cirrhosis, and diabetes, the aim of this study was to bring attention to this finding and provide clinical guidance to referring clinicians by inserting standardized text into radiology reports of patients with incidentally detected hepatic steatosis. METHODS: Patients with incidentally discovered hepatic steatosis on abdominal ultrasound or CT had standard text inserted into the impression sections of their diagnostic imaging reports. A total of 1,256 patients whose reports were tagged between April 2016 and September 2017 were retrospectively identified and their electronic medical records reviewed to determine subsequent acknowledgment in the medical record or clinical action in response to the tagged report. Information regarding patient demographics, the type of provider who ordered the examination, and the acuity of the examination results was also recorded. RESULTS: Acknowledgment and subsequent clinical action were more likely in patients whose examinations was ordered by primary care providers, whose examination results were not urgent, and who were in the ultrasound group. The overall diagnostic yield in patients who underwent clinical evaluation was nonalcoholic fatty liver disease in 70%, nonalcoholic steatohepatitis in 6%, and alcoholic hepatitis in 17%. CONCLUSIONS: Opportunistic screening for incidental hepatic steatosis on abdominal CT and ultrasound is feasible, with substantial yield for patients with clinically important entities including nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.


Subject(s)
Non-alcoholic Fatty Liver Disease , Follow-Up Studies , Humans , Liver Cirrhosis , Retrospective Studies , Ultrasonography
5.
BMJ Open Qual ; 7(3): e000273, 2018.
Article in English | MEDLINE | ID: mdl-30167473

ABSTRACT

Pancreatic extracorporeal shock wave lithotripsy followed by endoscopic retrograde cholangiopancreatography is accepted worldwide as a treatment for a large, symptomatic, obstructing pancreatic stones. However, timely completion of the combined process requires coordination of equipment and personnel from two different complex procedures. We used Lean management tools in a week-long event to redesign the process around the patient. Using idea-generated Plan Do Study Act cycles to refine the process, from scheduling to postprocedure recovery, equipment and personnel were aligned to allow these two procedures to occur in immediate succession. The redesigned process resulted in all patients receiving both procedures without delay. This eliminated over 8 hours of wait time. Standard work and a newly created complex scheduler improved flow. We reduced the number of anaesthetics for patients without prolonging the procedure length.

6.
J Am Geriatr Soc ; 65(5): 973-979, 2017 May.
Article in English | MEDLINE | ID: mdl-28182261

ABSTRACT

OBJECTIVES: To determine the effectiveness of a multifaceted quality improvement intervention in outpatient clinics at an integrated healthcare delivery system on capture rate of advance directives (ADs) in the electronic medical record (EMR). DESIGN: Interrupted time series analysis with control groups between January 2010 and June 2015. SETTING: Oncology, nephrology, and primary care outpatient clinics in an integrated healthcare delivery system. PARTICIPANTS: All individuals aged 65 and older with at least one office visit in any outpatient clinic in the care delivery system (n = 77,350 with 502,446 office visits). INTERVENTION: A series of quality improvement interventions to improve rates of advance care planning discussions and capture of those discussions in the EMR between 2010 and 2014. MEASUREMENTS: Capture rate of ADs in the EMR. RESULTS: Visits in the intervention primary care clinic were twice as likely to mention ADs in the EMR (53.4%) than visits in nonintervention primary care clinics (26.5%). Visits in the intervention oncology clinic were more than eight times as likely to mention ADs in the EMR (49.3% vs 6.0%), and visits in the intervention nephrology clinic were 2.5 times as likely to mention ADs (15.4% vs 6.0%) than visits in other specialty clinics. CONCLUSIONS: A series of quality improvement interventions to increase discussions about advance care planning and capture of advance care directives in the EMR significantly increased the rate of capture in primary care and specialty care outpatient settings.


Subject(s)
Advance Directives , Documentation/standards , Electronic Health Records , Quality Improvement , Advance Care Planning , Aged , Aged, 80 and over , Ambulatory Care Facilities , Female , Humans , Male
7.
J Healthc Qual ; 38(5): 275-82, 2016.
Article in English | MEDLINE | ID: mdl-26042758

ABSTRACT

INTRODUCTION: Quality improvement research skills are not commonplace among quality improvement practitioners, and research on the effectiveness of quality improvement has not always kept pace with improvement innovation. However, the Lean tools applied to quality improvement should be equally relevant to the advancement of quality improvement research. METHODS: We applied the Lean methods to develop a simplified quality improvement publication pathway enabling a small research methodology group to increase quality improvement research throughout the institution. The key innovations of the pathway are horizontal integration of the quality improvement research methods group across the institution, implementation of a Lean quality improvement research pathway, and application of a just-in-time quality improvement research toolkit. RESULTS: This work provides a road map and tools for the acceleration of quality improvement research. At our institution, the Lean quality improvement research approach was associated with statistically significant increases in the number (annual mean increase from 3.0 to 8.5, p = .03) and breadth of published quality improvement research articles, and in the number of quality improvement research projects currently in process. DISCUSSION: Application of Lean methods to the quality improvement research process can aid in increasing publication of quality improvement articles from across the institution.


Subject(s)
Health Services Research , Quality Improvement , Total Quality Management/methods , Delivery of Health Care/standards , Models, Theoretical
8.
Am J Health Syst Pharm ; 72(17): 1481-8, 2015 Sep 01.
Article in English | MEDLINE | ID: mdl-26294242

ABSTRACT

PURPOSE: The implementation of a custom alert to prevent medication-timing errors associated with the use of a computerized prescriber order-entry (CPOE) system is described. METHODS: In early 2013, Virginia Mason Medical Center began work to modify the CPOE system to make it impossible for a medication-timing error to occur. A visual control, a custom alert that forced prescribers to "self-inspect with pause" (a soft-stop override) before signing an order that may result in a medication-timing error, was developed. The prescriber could choose to modify the order to skip the next dose or change the start date or time of the order, cancel the order, or continue without altering the order. The custom alert was designed to fire only for medications that are administered once or twice daily. The effectiveness of the intervention was evaluated with interrupted time series before-and-after analysis of medication-timing errors. Outcomes measured included the proportion of errors that were corrected by the prescriber before signing the order and the number of medication-timing errors that reached patients. RESULTS: The proportion of orders where a prescriber modified the order as a result of the alert increased from 12% before the intervention to 29% postintervention (p > 0.001), and this percentage continued to increase at five months postintervention (p < 0.001). The percentage of medication-timing errors that reached the patient decreased by 50% in the postintervention period. CONCLUSION: Medication-timing errors associated with the use of a CPOE system were corrected through implementation of a customized alert.


Subject(s)
Medical Order Entry Systems , Medication Errors/prevention & control , Prescription Drugs/administration & dosage , Humans , Outcome Assessment, Health Care , Time Factors
9.
J Am Board Fam Med ; 28(2): 195-204, 2015.
Article in English | MEDLINE | ID: mdl-25748760

ABSTRACT

INTRODUCTION: To address unnecessary use of antibiotics for uncomplicated acute respiratory infection, we implemented a standardized care pathway composed of: (1) academic detailing of primary care providers, and (2) telephonic care from nurses. METHODS: To evaluate the intervention, we performed a retrospective time series study and cost analysis at a primary care provider network in the Pacific Northwest with 118 providers at seven sites. The main outcomes were: (1) antibiotic rate, (2) provider visits avoided, and (3) cost savings from the payer and health care system perspectives. Data were collected for January 2, 2010 to November 30, 2013, with the interventions occurring on March 1, 2012. RESULTS: There were 54,283 acute upper respiratory infection visits (34,678 [64%] female; average age, 52.1 years). After the intervention, nurse phone consultation involved 13.8% (3,289 of 23,769) of care episodes. The intervention was associated with a 16.5% absolute decrease in antibiotic rate (95% CI, -0.205 to -0.125; P < .001), after adjustment. Post intervention, 1983 of 23,769 (8.3%) episodes did not require any provider visit (1133 per year). Single institution cost savings to payers exceeded $175,000. CONCLUSIONS: Implementation of nurse phone care and provider academic detailing was associated with lower inappropriate antibiotic usage and fewer unnecessary provider visits.


Subject(s)
Anti-Bacterial Agents/pharmacology , Referral and Consultation , Respiratory Tract Infections/nursing , Telephone/statistics & numerical data , Unnecessary Procedures , Acute Disease , Female , Humans , Male , Middle Aged , Respiratory Tract Infections/drug therapy , Retrospective Studies
10.
Jt Comm J Qual Patient Saf ; 40(8): 341-50, 2014 Aug.
Article in English | MEDLINE | ID: mdl-25208439

ABSTRACT

BACKGROUND: Virginia Mason Medical Center (Seattle) employed the Lean concept of Jidoka (automation with a human touch) to plan for and deploy bar code medication administration (BCMA) to hospitalized patients. METHODS: Integrating BCMA technology into the nursing work flow with minimal disruption was accomplished using three steps ofJidoka: (1) assigning work to humans and machines on the basis of their differing abilities, (2) adapting machines to the human work flow, and (3) monitoring the human-machine interaction. Effectiveness of BCMA to both reinforce safe administration practices and reduce medication errors was measured using the Collaborative Alliance for Nursing Outcomes (CALNOC) Medication Administration Accuracy Quality Study methodology. Trained nurses observed a total of 16,149 medication doses for 3,617 patients in a three-year period. RESULTS: Following BCMA implementation, the number of safe practice violations decreased from 54.8 violations/100 doses (January 2010-September 2011) to 29.0 violations/100 doses (October 2011-December 2012), resulting in an absolute risk reduction of 25.8 violations/100 doses (95% confidence interval [CI]: 23.7, 27.9, p < .001). The number of medication errors decreased from 5.9 errors/100 doses at baseline to 3.0 errors/100 doses after BCMA implementation (absolute risk reduction: 2.9 errors/100 doses [95% CI: 2.2, 3.6,p < .001]). The number of unsafe administration practices (estimate, -5.481; standard error 1.133; p < .001; 95% CI: -7.702, -3.260) also decreased. CONCLUSION: As more hospitals respond to health information technology meaningful use incentives, thoughtful, methodical, and well-managed approaches to technology deployment are crucial. This work illustrates how Jidoka offers opportunities for a smooth transition to new technology.


Subject(s)
Automation/methods , Electronic Data Processing , Medication Systems, Hospital/organization & administration , Quality of Health Care/organization & administration , Workflow , Humans , Medication Errors/prevention & control , Patient Safety , Program Evaluation , User-Computer Interface
11.
J Hosp Med ; 9(10): 658-62, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25130651

ABSTRACT

BACKGROUND: We hypothesized that delirium contributes to combative behavior requiring intervention in hospitalized patients. Delirium identification would therefore potentially provide an opportunity for prevention and early identification of patients at risk, thereby improving safety for patients and staff. OBJECTIVE: To determine whether delirium is associated with combative behavior requiring intervention in a general hospital population. DESIGN: Case control study. SETTING: A 336-bed, nonuniversity, teaching hospital serving adults in the Pacific Northwest. PATIENTS: One hundred twenty consecutive hospitalized patients with combative behavior requiring intervention compared to 159 randomly selected inpatient control subjects, all from 2011. INTERVENTION: Bivariate statistics were used to compare demographics; diagnoses; presence of delirium, dementia, substance use, other psychiatric diagnosis; medications; hospital length of stay; and discharge disposition. We used stepwise logistic regression to determine the association of combative behavior requiring intervention with delirium after adjustment for covariates. RESULTS: Delirium preceding the combative behavior was present in 50% (60/120) of patients with combative behavior requiring intervention compared to 16% (26/159) of controls (P < 0.001). Combative-behavior patients were hospitalized longer (9.4 vs 4.5 days, P < 0.001), and were more likely to be discharged to a skilled nursing facility (26%, 31/120) or to leave against medical advice (10%, 12/120, P < 0.001). Delirium was strongly associated with combative behavior requiring intervention, after adjustment (odds ratio: 3.8, 95% confidence interval: 2.0-7.3, P < 0.001). CONCLUSION: Delirium is strongly associated with combative behavior requiring intervention, which poses a significant safety risk for patients and staff.


Subject(s)
Aggression , Delirium/epidemiology , Delirium/psychology , Adult , Aged , Aged, 80 and over , Case-Control Studies , Hospitals, Teaching , Humans , Hypnotics and Sedatives/administration & dosage , Length of Stay/statistics & numerical data , Logistic Models , Middle Aged , Narcotics/administration & dosage , Patient Discharge/statistics & numerical data , Risk Factors
12.
J Grad Med Educ ; 6(4): 750-5, 2014 Dec.
Article in English | MEDLINE | ID: mdl-26140131

ABSTRACT

BACKGROUND: Traditional "batched" bedside clinical care rounds, where rounds for all patients precede clinical tasks, may delay clinical care and reduce resident work efficiency. INNOVATION: Using Lean concepts, we developed a novel "Rounding-in-Flow" approach, with the patient care team completing all tasks for a single patient before initiating any tasks for the next patient. Outcome measures included timely patient discharge and intern work hours. METHODS: We performed a retrospective cohort study with historic and contemporaneous control groups, with time series adjustment for underlying temporal trends at a single medical center. Primary outcomes were timely patient discharge orders and resident duty hours. Participants were 17 376 consecutive hospital inpatients between January 1, 2011, and June 30, 2012, and medical ward rounding teams of interns, residents, and attending hospitalists. RESULTS: Timely discharge orders, defined as written by 9:00 am, improved from 8.6% to 26.6% (OR, 1.55; 95% CI 1.17-2.06; P  =  .003). Time of actual patient discharge was unchanged. Resident duty hour violations, defined as less than 10 hours between clinical duties, decreased from 2.96 to 0.98 per intern per rotation (difference, 1.98; 95% CI 1.09-2.87; P < .001). Average daily intern work hours decreased from 12.3 to 11.9 hours (difference, 0.4 hours; 95% CI 0.16-0.69; P  =  .002). CONCLUSIONS: Compared with batched rounding, Lean Rounding-in-Flow using "1-piece flow" principles was associated with more discharge orders written before 9:00 am and fewer violations in the 10-hour break rule, with minimal changes to intern total work hours and actual patient discharge time.

13.
Jt Comm J Qual Patient Saf ; 39(5): 195-204, 2013 May.
Article in English | MEDLINE | ID: mdl-23745478

ABSTRACT

BACKGROUND: At Virginia Mason Medical Center (Seattle), the Collaborative Alliance for Nursing Outcomes (CALNOC) Medication Administration Accuracy Quality Study was used in combination with Lean quality improvement efforts to address medication administration safety. METHODS: Lean interventions were targeted at improving the medication room layout, applying visual controls, and implementing nursing standard work. The interventions were designed to prevent medication administration errors through improving six safe practices: (1) comparing medication with medication administration record, (2) labeling medication, (3) checking two forms of patient identification, (4) explaining medication to patient, (5) charting medication immediately, and (6) protecting the process from distractions/interruptions. RESULTS: Trained nurse auditors observed 9,244 doses for 2,139 patients. Following the intervention, the number of safe-practice violations decreased from 83 violations/100 doses at baseline (January 2010-March 2010) to 42 violations/100 doses at final follow-up (July 2011-September 2011), resulting in an absolute risk reduction of 42 violations/100 doses (95% confidence interval [CI]: 35-48), p < .001). The number of medication administration errors decreased from 10.3 errors/100 doses at baseline to 2.8 errors/100 doses at final follow-up (absolute risk reduction: 7 violations/100 doses [95% CI: 5-10, p < .001]). The "perfect dose" score, reflecting compliance with all six safe practices and absence of any of the eight medication administration errors, improved from 37 in compliance/100 doses at baseline to 68 in compliance/100 doses at the final follow-up. CONCLUSION: Lean process improvements coupled with direct observation can contribute to substantial decreases in errors in nursing medication administration.


Subject(s)
Efficiency, Organizational/standards , Medication Errors/prevention & control , Medication Systems, Hospital/organization & administration , Nurse's Role , Process Assessment, Health Care , Safety Management/organization & administration , Adolescent , Adult , Aged , Aged, 80 and over , Chi-Square Distribution , Female , Health Services Research , Humans , Linear Models , Male , Organizational Case Studies , Quality Assurance, Health Care , United States , Virginia
14.
Jt Comm J Qual Patient Saf ; 39(3): 99-105, 2013 Mar.
Article in English | MEDLINE | ID: mdl-23516758

ABSTRACT

BACKGROUND: Surgical instrument processing is critical to safe, high-quality surgical care but has received little attention in the medical literature. Typical hospitals have inventories in the tens of thousands of surgical instruments organized into thousands of instrument sets. The use of these instruments for multiple procedures per day leads to millions of instrument sets being reprocessed yearly in a single hospital. Errors in the processing of sterile instruments may lead to increased operative times and costs, as well as potentially contributing to surgical infections and perioperative morbidity. METHODS: At Virginia Mason Medical Center (Seattle), a quality monitoring approach was developed to identify and categorize errors in sterile instrument processing, through use of a daily defect sheet. Lean methods were used to improve the quality of surgical instrument processing through redefining operator roles, alteration of the workspace, mistake-proofing, quality monitoring, staff training, and continuous feedback. To study the effectiveness of the quality improvement project, a before/after comparison of prospectively collected sterile processing error rates during a 37-month time frame was performed. RESULTS: Before the intervention, instrument processing errors occurred in 3.0% of surgical cases, decreasing to 1.5% at the final follow-up (p < .001). Improvements were observed in multiple categories of error types, particularly the assembly errors of packaging (from 0.66 to 0.24 errors per hundred cases, p = .004), and foreign objects (0.17 to 0.02 errors per hundred cases, p = .025). CONCLUSION: Surgical instrument processing errors are a barrier to the highest quality and safety in surgical care but are amenable to substantial improvement using Lean techniques.


Subject(s)
Infection Control/standards , Patient Safety/standards , Quality Assurance, Health Care/standards , Sterilization/standards , Surgical Instruments/standards , Academic Medical Centers , Humans , Infection Control/methods , Models, Organizational , Postoperative Complications/etiology , Postoperative Complications/microbiology , Postoperative Complications/prevention & control , Quality Assurance, Health Care/methods , Sterilization/methods , Surgical Instruments/microbiology , Washington
15.
Ann Allergy Asthma Immunol ; 103(3): 225-32, 2009 Sep.
Article in English | MEDLINE | ID: mdl-19788020

ABSTRACT

BACKGROUND: The Seattle Asthma Severity and Control Questionnaire (SASCQ) was designed as a short, sensitive, and quantitative measure of asthma severity, impairment, and risk. OBJECTIVES: To evaluate the distribution of responses to the SASCQ in a diverse asthma population and to determine whether the questionnaire is associated with other measures of asthma severity and control. METHODS: A cross-sectional study of 188 asthmatic patients was conducted in a large academic primary care network. Asthma severity was confirmed in a subgroup of 44 patients by means of an in-person interview and lung function measurement. RESULTS: The SASCQ score had a nearly normal distribution across the heterogeneous population and less of a floor effect than the number of asthma-free days. The SASCQ score showed a higher symptom burden in the mildest asthmatic patients compared with nonasthmatic controls. Asthma severity evaluated using the questionnaire was correlated with asthma severity evaluated by means of in-person interview and with controller medication class. The SASCQ score was associated with primary care visits for asthma, emergency department treatment for asthma, days missed from work, and confidence to control asthma symptoms; the associations between these measures of impairment and risk were all stronger for the SASCQ score than for asthma-free days. CONCLUSIONS: The SASCQ is a quantitative measure of asthma that accurately discriminates between established levels of asthma severity and that is associated with other measures of asthma control and risk.


Subject(s)
Asthma/diagnosis , Surveys and Questionnaires , Adolescent , Adult , Aged , Aged, 80 and over , Asthma/epidemiology , Asthma/physiopathology , Child , Cross-Sectional Studies , Disease Progression , Emergency Medical Services/statistics & numerical data , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Reproducibility of Results , Respiratory Function Tests , Severity of Illness Index
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