Perfil de sensibilização a aeroalérgenos e alimentos em pacientes com dermatitie atópica do HSPE-SP / Sensitization profile in atopic dermatitis patients from HSPE-SPto airborne and food allergens

Objetivos: Avaliar o perfil de sensibilização a aeroalérgenos e alimentos de pacientes com dermatite atópica do ambulatório de alergia e imunologia do Hospital do Servidor Público Estadual de São Paulo (HSPE-SP) e estabelecer sua associação com alergia alimentar. Método: Estudo prospectivo de pacientes que preencheram os critérios para dermatite atópica do ambulatório de alergia e imunologia do (HSPE-SP) entre 2004 a 2006. Os participantes responderam questionário específico e foram avaliados quanto à gravidade das lesões conforme o SCORAD pelo médico e por ele mesmo através de 'uma escala visual analógica de sintomas. Foram solicitados IgE sé rica total, IgE sé rica específica e teste cutâneo de leitura imediata com aeroalérgenos e alimentos. Resultados: Foram avaliados 110 pacientes, com idades entre 1 e 66 anos (média 15,8 anos), predominando a fase de .escolar (29). Vinte e seis (23,6...

Autotransplantation for treatment of severe splenic lesions.

The aim of the study was to evaluate clinical and laboratory variables in patients undergoing spleen autotransplantation. We studied 29 patients with severe trauma of the spleen and its pedicle. Of these, 20 underwent autotransplantation (group I) and 9 underwent total splenectomy without preservation of splenic tissue (group II). Twenty-two additional subjects with an intact spleen were used as controls (group III). Immediate and late postoperative complications were investigated. Laboratory counts were performed during the late postoperative period (red blood cells, hemoglobin, white blood cells, platelets, and Howell-Jolly bodies). To investigate the immunological profiles of patients we performed B- and T-lymphocyte counts and determined IgA, IgG, and IgM levels. All patients underwent splenic scintigraphy with technetium 99m sulfur colloid. Groups I and III did not present abnormal blood bodies, and their hematological and immunological patterns were normal. Group II showed increased numbers of Howell-Jolly bodies and low IgM levels. Splenic scintigraphy indicated the viability and filtering function of the splenic remnant in group I. Autotransplantation is a good option to maintain splenic function when total splenectomy is necessary.

Analysis of malignancy detected by needle-localized breast biopsy.

The medical records of 192 women with nonpalpable mammographically detected breast lesions who underwent needle-localized breast biopsy between January 1989 and January 1991 and between March 1992 and March 1994 were reviewed. Of the 192 patients examined, 100 underwent biopsy for evaluation of microcalcifications suggestive of malignancy. Ninety-two biopsies were performed for non-specific radiodensities not inclusive of microcalcifications. This study examines the radiographic characteristics of the nonpalpable breast lesion. Although presence of microcalcifications on mammograms are an important finding in detection of breast carcinoma, it must not be considered pathognomonic. Other distinguishing factors require evaluation to assess the indication for biopsy. Central to this study was the presence of microcalcifications alone or as detected in association with a dominant mass. Cancer was discriminated in 38 (20%) of the patients studied. Mammographic findings with microcalcification, regardless of the presence of a mass, were found to be malignant in 20% of patients undergoing biopsy. Nine percent of biopsies done to evaluate microcalcifications alone were malignant. The finding of microcalcification associated with a dominant mass proved malignant in 34% of patients who had a biopsy done. The authors include guidelines for increasing the effectiveness of needle-localized biopsies of the breast.

A follow-up study of disturbed children treated in a Re-ED program.

In 1974 the authors undertook an evaluation of the children's program at Marshall I. Pickens Hospital in Greenville, South Carolina. The program, based on the Re-ED model, accepts only boys of normal intelligence between the ages of six and 12; most are referred because of disruptive behavior in the classroom and at home and low academic achievement. To evaluate the program, questionnaires were mailed to the families of all children who had been discharged from the program six months or longer a total of 123. Sixty-three of the 101 parents responding said the program had provided very much help for their child. At follow-up 89 children were enrolled in some kind of school program, and one had graduated from high school. However, 66 parents reported their child continued to have academic problems. The authors compare the findings with follow-up studies of three other Re-ED programs and discuss possible modifications that might make such programs more effective for children who fail to adjust.