1.
Bioorg Med Chem Lett
; 13(23): 4179-86, 2003 Dec 01.
Article
in English
| MEDLINE
| ID: mdl-14622997
ABSTRACT
Exploration of the structure-activity relationships of the traditional C-5 acetamidomethyl side chain of the oxazolidonone antibacterials has yielded new, potent series of compounds of which the first examples, the O-linked iosoxazoles are described in detail, leading to the selection of the pre-clinical candidate AZD2563.