ABSTRACT
Applied potential tomography was used to measure changes in gastric emptying during the peripartum period. Gastric emptying was measured sequentially in each of 10 healthy patients at 37-40 weeks gestation, 2-3 days postpartum and after the 6-week postnatal assessment (control). Mean (SD) times to 50% emptying were 15 (6.05), 11 (5.9) and 15 (5.5) min, respectively. There was no statistically significant change in gastric emptying as a result of pregnancy in this group of women. Retrospective power analysis (assuming alpha = 0.05 and beta = 0.20) shows the study design was adequate to detect a difference of 8 min.
Subject(s)
Gastric Emptying/physiology , Pregnancy/physiology , Adult , Female , Humans , Postpartum Period/physiology , Pregnancy Trimester, Third , Time Factors , TomographyABSTRACT
The effect of buprenorphine 0.2 mg sublingually on gastric emptying of a liquid meal in 10 volunteers was compared with placebo. Gastric emptying was measured by applied potential tomography and was delayed significantly by buprenorphine (P less than 0.001).
