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1.
BMC Surg ; 8: 19, 2008 Oct 31.
Article in English | MEDLINE | ID: mdl-18976456

ABSTRACT

BACKGROUND: For many patients with aorto-occlusive disease, where stent deployment is not possible, surgery remains the only treatment option available. The aim of this study was to assess the results of aortic reconstruction surgery performed in patients with critical ischaemia. METHODS: All patients with critical ischaemia undergoing surgery during 1991-2004 were identified from a prospectively maintained database. Mortality data was verified against death certificate data. Demographic and clinical data were obtained from the clinical notes and the radiology database. Disease was classified as: type I - limited to aorta and common iliac arteries; type II - external iliac disease and type III combined aortic, iliac and infra-inguinal disease. RESULTS: 86 patients underwent aortic replacement surgery all of whom had critical ischaemia consisting of: type I (n = 16); type II (n = 37) and type III (n = 33). The 30-day mortality rate was 10.4%, the one-year patient survival was 80%, and the 1-year graft survival was 80%. At 2 years the actual patient survival was 73% and no additional graft losses were identified. All patients surviving 30 days reported excellent symptomatic relief. Early, complications occurred in 6 (7%) patients: thrombosis within diseased superficial femoral arteries (n = 4); haemorrhage and subsequent death (n = 2). Ten (14%) late complications (> 12 months) occurred in the 69 surviving patients and included: anastomotic stenosis (n = 3); graft thrombosis (n = 4), graft infection (n = 3). Four patients developed claudication as a result of more distal disease in the presence of a patent graft, and 1 patient who continued smoking required an amputation for progressive distal disease. CONCLUSION: Aortic reconstruction for patients with extensive aorto-occlusive disease provides long-standing symptomatic relief for the majority of patients. After the first year, there is continued patient attrition due to co-existent cardiovascular disease but no further graft losses.


Subject(s)
Aorta, Abdominal/surgery , Aortic Diseases/surgery , Arterial Occlusive Diseases/surgery , Blood Vessel Prosthesis Implantation/methods , Adult , Aged , Aged, 80 and over , Aortic Diseases/mortality , Arterial Occlusive Diseases/mortality , Female , Follow-Up Studies , Humans , Male , Middle Aged , Prospective Studies , Survival Rate/trends , Time Factors , Treatment Outcome , United Kingdom/epidemiology
2.
Clin Exp Ophthalmol ; 34(6): 609-10, 2006 Aug.
Article in English | MEDLINE | ID: mdl-16925712

ABSTRACT

A 74-year-old man presented with a 4-month history of swelling in the right upper lid. Biopsy of the lesion showed moderate to poorly differentiated invasive squamous cell carcinoma. He was recently diagnosed with squamous carcinoma of the lung with similar histology to the eyelid lesion. Eyelid metastases are a rare presentation of lung tumours.


Subject(s)
Carcinoma, Squamous Cell/secondary , Eyelid Neoplasms/secondary , Lung Neoplasms/pathology , Aged , Carcinoma, Squamous Cell/diagnostic imaging , Carcinoma, Squamous Cell/surgery , Eyelid Neoplasms/diagnosis , Eyelid Neoplasms/surgery , Fatal Outcome , Humans , Lung Neoplasms/diagnostic imaging , Male , Tomography, X-Ray Computed
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