ABSTRACT
Using a method combining the velocity of ultrasound and photon absorptiometry in the human radius in vivo, the authors measured the speed of sound in bone (U) and bone mineral content (BMC). From these measurements and a "simple" bone model, they then computed the bone mineral density, compact bone density, and modulus of elasticity. The accuracy of these parameters and of the bone model is assessed, and normal values for each parameter are given and compared with published values. The authors feel that a combination of U and BMC permits better discrimination between normal and abnormal in patients with osteoporosis or metabolic bone disease than either parameter alone.
Subject(s)
Bone Diseases, Metabolic/diagnosis , Osteoporosis/diagnosis , Ultrasonography , Adolescent , Adult , Bone and Bones/analysis , Bone and Bones/diagnostic imaging , Densitometry , Elasticity , Female , Humans , Male , Middle Aged , Minerals/analysis , Osteoporosis/diagnostic imaging , RadiographyABSTRACT
The modulus of elasticity was derived by combining the velocity of ultrasound measurements and photon absorption (Norland-Cameron method) in human cortical bone (proximal radius) in vivo. The results compare favorably with published values of the elasticity modulus obtained in vitro. Values obtained for a heterogeneous group of patients with bone and joint complaints differed from those of normal volunteers.