[Use of fructosamine serum level measurements for diagnosis of insulin-dependent diabetic in pregnancy]. / Zastsosowanie oznaczania stezenia fruktozaminy w surowicy krwi do rozpoznania cukrzycy ciezarnych, wymagajacej leczenia insulina.

In this study it has been tested the usefulness of serum glycosyl protein (fructosamine) to diagnose diabetic pregnant women requiring insulin therapy. The analysis was performed on the base of obtained results of glucose tolerance test, glycemia level in diurnal profile, fructosamine level and its relationship to albumin level and total protein amount in serum pregnant women with carbohydrates intolerance. Calculated specificity and sensitivity of above mentioned measurements was too low. We can not concluded that it is necessary to include insulin-therapy in diabetic pregnancy on the base of fructosamine serum level even corrected by protein or albumin serum level.

[A proposed model of the treatment of diabetes mellitus in pregnancy]. / Propozycja modelu postepowania w leczeniu chorych na cukrzyce w czasie ciay.

A model of management of pregnant diabetic patients is proposed. Such a model has been implemented at the Voivodeship Out-patient Clinic for Diabetics. Proposed model includes recent data on diabetes mellitus complications and the effect of coexisting diseases on the mother and fetus health. Management was adapted to the real and potential possibilities of health service in Poland. A decrease in the rate of mortality of fetuses under 7% was achieved. It is worth emphasizing despite higher value than those reported in the literature.

[Growth hormone, insulin and placental lactogen in the sera of mothers and fetal blood of infants from physiological pregnancy and pregnancy complicated by diabetes mellitus]. / Hormon wzrostu, insulina i laktogen lozyskowy w surowicy krwi matek oraz krwi pepowinowej noworodków z ciazy fizjologicznej i powiklanej cukrzyca.

The study was aimed at investigating the changes in the blood serum concentrations of growth hormone (HGH), insulin and placental lactogen (HPL) in the newborns of diabetic mothers as compared to those born from physiological pregnancies. The concentration of hormones was determined by RIA both in the newborns and in mothers of the two groups. The mean insulin concentration was significantly higher, and that of HGH significantly lower in the newborns of diabetic mothers, as compared to those of healthy mothers. It seems that the occurrence of fetal macrosomy in diabetic pregnancies is associated with high insulin levels.