Theory of mind in remitted bipolar disorder: Younger patients struggle in tasks of higher ecological validity.

BACKGROUND: To date, research concerning Theory of Mind (ToM) in remitted bipolar disorder (rBD) has yielded inconclusive results. This may be a result of methodological shortcomings and the failure to consider relevant third variables. Furthermore, studies using ecologically valid stimuli are rare. This study examines ToM in rBD patients, using ecologically valid stimuli. Additionally, the effects of sad mood induction (MI) as well as of age and gender are considered. METHODS: The sample comprises N = 44 rBD patients (rBDPs) and N = 40 healthy controls (HCs). ToM decoding is assessed using the Cambridge Mindreading Face-Voice-Battery (CAM) and ToM reasoning using the Movie for the Assessment of Social Cognition (MASC). Both tasks were divided into two parts to conduct one part with and one without MI. RESULTS: While across the whole sample there was no evidence that rBDPs and HCs differed in ToM decoding or reasoning, in the younger subsample (age < 45) rBDPs performed worse than HCs in ToM decoding. While MI negatively influenced reasoning in both groups, gender had no effect. LIMITATIONS: Most patients in this study had a high level of social functioning, limiting the generalizability of the results. CONCLUSION: As important social steps have to be undertaken before middle-age, the decoding deficits in younger rBDPs might be of particular importance not only for social functioning but also for the course of illness. Furthermore, this age-related deficit may explain the inconclusive findings that have been reported so far.

Reading sentences describing high- or low-pitched auditory events: only pianists show evidence for a horizontal space-pitch association.

This study explored differences between pianists and non-musicians during reading of sentences describing high- or low-pitched auditory events. Based on the embodied model of language comprehension, it was hypothesized that the experience of playing the piano encourages a corresponding association between high-pitched sounds and the right and low-pitched sounds and the left. This pitch-space association is assumed to become elicited during understanding of sentences describing either a high- or low-pitched auditory event. In this study, pianists and non-musicians were tested based on the hypothesis that only pianists show a compatibility effect between implied pitch height and horizontal space, because only pianists have the corresponding experience with the piano keyboard. Participants read pitch-related sentences (e.g., the bear growls deeply, the soprano singer sings an aria) and judged whether the sentence was sensible or not by pressing either a left or right response key. The results indicated that only the pianists showed the predicted compatibility effect between implied pitch height and response location. Based on the results, it can be inferred that the experience of playing the piano led to an association between horizontal space and pitch height in pianists, while no such spatial association was elicited in non-musicians.

Musical metaphors: evidence for a spatial grounding of non-literal sentences describing auditory events.

This study investigated whether the spatial terms high and low, when used in sentence contexts implying a non-literal interpretation, trigger similar spatial associations as would have been expected from the literal meaning of the words. In three experiments, participants read sentences describing either a high or a low auditory event (e.g., The soprano sings a high aria vs. The pianist plays a low note). In all Experiments, participants were asked to judge (yes/no) whether the sentences were meaningful by means of up/down (Experiments 1 and 2) or left/right (Experiment 3) key press responses. Contrary to previous studies reporting that metaphorical language understanding differs from literal language understanding with regard to simulation effects, the results show compatibility effects between sentence implied pitch height and response location. The results are in line with grounded models of language comprehension proposing that sensory motor experiences are being elicited when processing literal as well as non-literal sentences.