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1.
Eur Spine J ; 24(12): 2872-9, 2015 Dec.
Article in English | MEDLINE | ID: mdl-25787945

ABSTRACT

BACKGROUND: No previous reports have mentioned bone loss of the superior adjacent vertebra immediately posterior to the anterior flange of Bryan cervical disc (Medtronic Sofamor Danek, Memphis, TN, USA), which plays a central role to prevent posterior migration of the device. The purpose of this study is to describe a new potential complication, bone loss immediately posterior to the anterior total disc replacement (TDR) flange on the superior adjacent vertebra following the Bryan cervical TDR and to discuss the possible mechanism. METHODS: The authors retrospectively reviewed 37 patients undergoing cervical TDR with the Bryan cervical disc. The clinical and radiological outcome data were collected at 1, 3, 6, 12, 24, and 36 months postoperatively, and at last follow-up, which ranged from 42 to 113 moths (average, 60.1 months). Clinical evaluation included the visual analog scale and neck disability index, and the radiographic evaluation included measurements of the functional spinal unit range of motion on flexion and extension and identification of radiographic changes such as bone loss. RESULTS: The Bryan TDR showed good mid-term clinical and radiological outcomes. Interestingly, however, bone loss was noted immediately posterior to the TDR flange on superior adjacent vertebra in 3 total patients; at 3 months (n = 2) and 6 months (n = 1). Although the bone loss was increased up to 6 months, this did not progress and no degradation of clinical and radiological outcomes occurred at last follow-up. CONCLUSIONS: Bone loss immediately posterior to the anterior TDR flange on the superior adjacent vertebra can occur in the early postoperative period due to possibly stress shielding effect. However, it did not result in clinical changes or increased rates of graft failure at last follow-up. A long-term follow-up study is mandatory to evaluate the long-term effects of the bone loss.


Subject(s)
Bone Diseases, Metabolic/etiology , Cervical Vertebrae/surgery , Intervertebral Disc Degeneration/etiology , Intervertebral Disc Degeneration/surgery , Joint Prosthesis , Postoperative Complications/etiology , Total Disc Replacement/adverse effects , Adult , Cervical Vertebrae/diagnostic imaging , Disability Evaluation , Female , Follow-Up Studies , Humans , Male , Middle Aged , Pain Measurement , Radiography , Retrospective Studies , Treatment Outcome
2.
J Neurosurg Pediatr ; 15(4): 384-91, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25580513

ABSTRACT

Intracranial intravascular papillary endothelial hyperplasia (IPEH) is very rare, and to our knowledge long-term follow-up results have not been previously published. An 11-year-old boy presented with a 6-month history of progressive visual impairment in the right eye. Magnetic resonance imaging revealed a well-enhanced, large parasellar mass involving the cavernous sinus, right frontal skull base, and ethmoid and sphenoid sinuses. Frontotemporal craniotomy and subtotal resection were performed, and the diagnosis of IPEH was confirmed. The mass increased in size during the following 3 months. A second operation was performed via frontotemporal craniotomy combined with a transsphenoidal approach, and gross-total resection of the tumor was achieved. Adjuvant radiotherapy (5040 cGy) and chemotherapy with interferon were administered. The patient's visual symptoms improved, and there was no recurrence during a 13-year follow-up period. The results of this case indicate that intracranial IPEH can recur with subtotal resection; however, optimal resection with multimodal adjuvant treatment can control the disease for many years, if not permanently.


Subject(s)
Cavernous Sinus/pathology , Endothelium, Vascular/pathology , Neoplasms, Vascular Tissue/diagnosis , Neoplasms, Vascular Tissue/surgery , Orbit/blood supply , Paranasal Sinus Neoplasms/diagnosis , Paranasal Sinus Neoplasms/surgery , Vision Disorders/etiology , Antineoplastic Agents/therapeutic use , Chemotherapy, Adjuvant , Child , Craniotomy , Ethmoid Sinus/blood supply , Humans , Hyperplasia/diagnosis , Hyperplasia/etiology , Interferons/administration & dosage , Magnetic Resonance Imaging , Male , Neoplasms, Vascular Tissue/pathology , Papilledema/etiology , Paranasal Sinus Neoplasms/complications , Paranasal Sinus Neoplasms/pathology , Radiotherapy, Adjuvant , Reoperation , Skull Base/blood supply , Sphenoid Sinus/blood supply , Tomography, X-Ray Computed , Treatment Outcome
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