ABSTRACT
We describe a case of cutaneous leishmaniasis with lymphadenopathy due to Leishmania donovani, which was successfully treated with oral miltefosine. Given the increased prevalence of travelling, patients presenting with lymph-node enlargement should have leishmaniasis included in the differential diagnosis even in the absence of typical ulceration.
Subject(s)
Facial Dermatoses/diagnosis , Leishmania donovani , Leishmaniasis, Cutaneous/diagnosis , Lymphatic Diseases/parasitology , Animals , Antiprotozoal Agents/therapeutic use , Facial Dermatoses/drug therapy , Female , Humans , Leishmaniasis, Cutaneous/complications , Leishmaniasis, Cutaneous/drug therapy , Lymphatic Diseases/drug therapy , Middle Aged , Phosphorylcholine/analogs & derivatives , Phosphorylcholine/therapeutic useABSTRACT
An allergic reaction develops in 2.4% of patients that use insulin. This ranges in severity from erythema and pruritus to life-threatening anaphylaxis. llergic reactions to insulin usually occur within a few hours after an injection and are usually due to a local or systemic type I IgE-mediated hypersensitivity reaction. Despite considerable research into the immunogenicity of insulin, this has not yet been clarified completely and allergic reactions to insulin still occur. A systematic diagnostic approach is essential for an adequate treatment plan. A blood test for anti-insulin antibodies and intradermal skin tests are of great importance. There are many options available for the treatment of insulin allergy and each patient must therefore be evaluated individually.
Subject(s)
Diabetes Mellitus, Type 1/drug therapy , Drug Hypersensitivity/etiology , Hypoglycemic Agents/adverse effects , Insulin Antibodies/blood , Insulin/adverse effects , Anaphylaxis/etiology , Drug Hypersensitivity/diagnosis , Drug Hypersensitivity/therapy , Erythema/chemically induced , Humans , Hypoglycemic Agents/immunology , Hypoglycemic Agents/therapeutic use , Insulin/immunology , Insulin/therapeutic use , Intradermal Tests , Pruritus/chemically inducedABSTRACT
Post-traumatic stress disorder (PTSD), previously defined in Vietnam War veterans, was described in 251 Desert Storm reservists. The Mississippi Scale, Revised, was used with a brief demographic profile to survey Army, Marine, and Air Force personnel who had been deployed to Saudi Arabia. Age, sex, marital status, race, rank, duty, length of deployment, and branch of service were not found to be significantly related to PTSD symptoms. However, those surveyed within 3 to 6 months of homecoming reported significantly greater symptoms than those surveyed after 6 months. Five percent of subjects were found to have clinically diagnostic levels of PTSD symptoms 6 months after homecoming. Individuals who expressed difficulty discussing their experiences with more than one person also showed significantly higher PTSD scores. These findings indicate that readjustment reactions were prevalent during the first 6 months and that PTSD could be identified in 5% of the Desert Storm veterans.
Subject(s)
Combat Disorders/psychology , Military Personnel/psychology , Warfare , Adult , Combat Disorders/diagnosis , Female , Humans , Male , Middle East , Psychiatric Status Rating ScalesABSTRACT
The effects of light-induced non-photochemical quenching on the minimal Fo, and variable Fv, fluorescence emissions at 690 and 730 nm in leaves were determined. Non-photochemical quenching of Fo, but not Fv, was found to be dependent upon the wavelength of emission, and was greater at 690 nm than at 730 nm. For emission at 730, compared to at 690 nm, approx. 30% of Fo was not affected by non-photochemical quenching processes in leaves of C3 plants; in maize leaves this was found to be approx. 50%. The data indicate that a substantial proportion of the pigments contributing to Fo emission at 730 nm are not quenched by light-induced, non-photochemical quenching processes and that there are large differences in the pigment matrices contributing to Fo and Fv emissions at 730 nm, compared to those at 690 nm. These findings have important implications for the accurate estimation and interpretation of non-photochemical quenching of fluorescence parameters and their use in the calculation of photochemical efficiencies in leaves. Measurements of fluorescence emissions at wavelengths above 700 nm are likely to give rise to significant errors when used for determinations of photochemical and non-photochemical quenching parameters.
