1.
Pediatr Blood Cancer
; 69(12): e30012, 2022 12.
Article
in English
| MEDLINE
| ID: mdl-36129388
ABSTRACT
We assessed the utility of routine viral surveillance for cytomegalovirus, Epstein-Barr virus and human adenovirus in children <16 years, undergoing autologous stem cell transplantation (ASCT) at a single centre over a 10-year period. A total of 85 ASCT were performed in 65 patients. Routine viral surveillance resulted in a high number of tests performed (median 20 tests per ASCT), without any clinically significant viral detections. These data support the limited clinical utility of routine viral surveillance in children undergoing ASCT. Adopting a clinically driven approach for viral testing is likely to be both cost-effective and safe.
Subject(s)
Cytomegalovirus Infections , Epstein-Barr Virus Infections , Hematopoietic Stem Cell Transplantation , Child , Humans , Transplantation, Autologous , Herpesvirus 4, Human , Stem Cell Transplantation/adverse effects , Stem Cell Transplantation/methods , Retrospective Studies
2.
Arch Dis Child
; 107(5): 517-519, 2022 05.
Article
in English
| MEDLINE
| ID: mdl-34930725