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5.
Dermatol Clin ; 29(2): 153-60, vii, 2011 Apr.
Article in English | MEDLINE | ID: mdl-21421141

ABSTRACT

This article reviews Mohs micrographic surgery for basal cell carcinoma. Its evolution to the present day technique, indications, and limitations are discussed, along with future expectations for the procedure.


Subject(s)
Carcinoma, Basal Cell/surgery , Mohs Surgery/methods , Skin Neoplasms/surgery , Carcinoma, Basal Cell/pathology , Humans , Skin Neoplasms/pathology
6.
Dermatol Ther ; 24(6): 558-70, 2011.
Article in English | MEDLINE | ID: mdl-22515671

ABSTRACT

Although the infection rate of dermatologic procedures is extremely low, it is important to understand the serious complications that may result from one of these rare events. With the ever increasing number of dermatologic procedures performed, research continues to build regarding cutaneous infections. In order to properly treat a surgical site infection, the etiology and course of the infection must be known. The common microbes, types of infections, prophylaxis, and treatments involved in dermatologic surgery are reviewed.


Subject(s)
Cosmetic Techniques/adverse effects , Dermatologic Surgical Procedures , Skin Diseases, Infectious/etiology , Surgical Wound Infection/etiology , Humans , Risk Assessment , Risk Factors , Skin Diseases, Infectious/prevention & control , Skin Diseases, Infectious/therapy , Surgical Wound Infection/prevention & control , Surgical Wound Infection/therapy , Treatment Outcome
7.
Am J Dermatopathol ; 32(8): 764-8, 2010 Dec.
Article in English | MEDLINE | ID: mdl-20559119

ABSTRACT

Spindle cell lipoma (SCL), dermatofibrosarcoma protuberans (DFSP), and solitary fibrous tumors (SFT) are cutaneous CD34+ spindle cell tumors that may exhibit histopathologic and immunophenotypic overlap. We sought ways to reliably distinguish among these lesions even in small or superficial biopsies. Ten morphologic characteristics were analyzed in a group of 5 SCLs, 6 cutaneous SFTs, and 12 DFSPs. SFT and DFSP exhibited extensive histopathologic overlap in small or partial biopsies. However, adnexal entrapment, defined as diffuse proliferation of tumor cells around pilosebaceous and eccrine structures with minimal disruption or expansion of the dermis, was a feature seen in 10 of the 12 DFSPs and in none of the SFTs or SCLs. Even when only superficial portions of a lesion were present, this feature was identifiable. Spindle cell lipomas posed little diagnostic difficulty, in part because excisional biopsies were performed in all cases of SCL. The number of samples included in the study is relatively small, in part due to the rarity of cutaneous solitary fibrous tumors. We conclude that careful attention to these histopathologic features enables reliable distinction among these tumors.


Subject(s)
Antigens, CD34/analysis , Lipoma/pathology , Skin Neoplasms/pathology , Skin/pathology , Solitary Fibrous Tumors/pathology , Adult , Aged , Aged, 80 and over , Biopsy , Dermatofibrosarcoma/immunology , Dermatofibrosarcoma/pathology , Diagnosis, Differential , Female , Humans , Immunohistochemistry , Immunophenotyping , Lipoma/immunology , Male , Middle Aged , Pennsylvania , Predictive Value of Tests , Skin/immunology , Skin Neoplasms/immunology , Solitary Fibrous Tumors/immunology
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