ABSTRACT
We investigated the mortality associated with Acinetobacter baumannii complex bacteremia among a cohort of patients hospitalized for war-related trauma. Despite a high prevalence of multidrug-resistant strains, the 30-day mortality rate was 2%. For relatively young patients with war-related trauma, A. baumannii complex bacteremia appears to be associated with a low risk of death.
Subject(s)
Acinetobacter baumannii/isolation & purification , Bacteremia/mortality , Military Personnel , Warfare , Wounds and Injuries/etiology , Acinetobacter Infections/microbiology , Acinetobacter Infections/mortality , Acinetobacter baumannii/classification , Adolescent , Adult , Bacteremia/microbiology , District of Columbia , Female , Hospitals, Military/statistics & numerical data , Humans , Male , Young AdultABSTRACT
Nitrofurantoin is a commonly used antibiotic for the prophylaxis and treatment of urinary tract infections. We report the first case of nitrofurantoin-induced systemic inflammatory response syndrome, an important adverse drug reaction in the setting of what was initially believed to be a recurrent infection.
Subject(s)
Gram-Negative Bacterial Infections/drug therapy , Nitrofurantoin/adverse effects , Stenotrophomonas/isolation & purification , Systemic Inflammatory Response Syndrome/chemically induced , Aged , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Escherichia coli Infections/complications , Escherichia coli Infections/drug therapy , Gram-Negative Bacterial Infections/microbiology , Humans , Male , Nitrofurantoin/therapeutic use , Systemic Inflammatory Response Syndrome/complications , Urinary Bladder Neoplasms/complications , Urinary Bladder Neoplasms/drug therapyABSTRACT
Q fever, a zoonosis caused by Coxiella burnetii, is seen throughout the world. Recent reports suggest that its incidence in the United States is increasing, with more than 30 cases reported in the US military. The disease has many acute and chronic manifestations. Endocarditis is the most common form of chronic disease, and recent studies have led to substantial changes in the approach to its diagnosis and treatment. Military and civilian health care professionals need to consider Q fever when evaluating patients with appropriate geographic exposures and clinical presentations to prevent delays in diagnosis and treatment.
Subject(s)
Q Fever/diagnosis , Acute Disease , Anti-Bacterial Agents/therapeutic use , Bacterial Vaccines , Chronic Disease , Doxycycline/therapeutic use , Endocarditis, Bacterial/microbiology , Endocarditis, Bacterial/therapy , Female , Humans , Military Personnel , Pregnancy , Pregnancy Complications, Infectious/therapy , Q Fever/epidemiology , Q Fever/therapy , United States/epidemiologyABSTRACT
Q fever is an emerging infectious disease among US soldiers serving in Iraq. Three patients have had atypical manifestations, including 2 patients with acute cholecystitis and 1 patient with acute respiratory distress syndrome. Providers must be aware of Q fever's signs and symptoms to avoid delays in treatment.
